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Biomedical subjects

K Furuya

Publications and source records attributed to K Furuya.

At least 397 records · Page 22Linked to original sources

A new method to determine adequate requirements of electrolytes in intravenous nutrition.

(1) The amount of urinary electrolyte excretion is compared with nitrogen balance to determine an adequate requirement of electrolytes. The principle of this method is based on the relationship between the change of nitrogen balance and of ICF volume. (2) The adequate concentration of inorganic phosphorus and of potassium are estimated as about 1 mM/1 and 30 mEq/1 respectively, where the solution contains 27.4 g of nitrogen and 181.8 g of glucose per 1 liter. As far as sodium, chloride, magnesium and calcium, no reliable estimates are obtained. (3) The principle and the method are proved to be valid under some limitations.

Electrolytes↗

Effects of cations on dipalmitoyl phosphatidylcholine/cholesterol/water systems.

X-ray diffraction studies have been made on the effects of cations upon the dipalmitoyl phosphatidylcholine/water system, which originally consists of a lamellar phase with period of 64.5 A and of excess water. Addition of 1 mM CaCl2 destroys the lamellar structure and makes it swell into the excess water. The lamellar phase, however, reappears when the concentration of CaCl2 increases: a partially disordered lamellar phase with the repeat distance of 150-200 A comes out at the concentration of about 10 mM, the lamellar diffraction lines become sharp and the repeat distance decreases with increasing CaCl2 concentration. A small amount of uranyl acetate destroys the lameellar phase in pure water. MgCl2 induces the lamellar phase of large repeat distance, whereas LiCl, NaCl, KCl, SrCl2 and BaCl2 exhibit practically no effect by themselves. Addition of cholesterol to the phosphatidylcholine bilayers tends to stabilize the lamellar phase. The high-angle reflections indicate that molecular arrangements in phosphatidylcholine bilayers change at CaCl2 concentrations around 0.5 M. The bilayers at high CaCl2 concentration seem to consist of two phases of pure phosphatidylcholine and of equimolar mixture of phosphatidylcholine and cholesterol.

Calcium↗