Search PubMed⌕ Search

Biomedical subjects

K Fukuda

Publications and source records attributed to K Fukuda.

At least 847 records · Page 47Linked to original sources
PubMed1985

Epidemiologic study of carcinoma in situ of the cervix.

From 1950 to 1979, 1,248 cases of cancer in situ were treated in the Department of Gynecology, Cancer Institute Hospital, Tokyo. Detailed data were obtained from 585 of the patients by interview. Many patients had had their first sexual experience at an early age. Many had had more than two sexual partners, and there was a large discrepancy between the age at first sexual intercourse and at first marriage. The above factors seem to be related to the development of cancer in situ.

Abortion, Legal↗
PubMed1985

Pericentral pigmentary retinal degeneration.

We studied five patients with pericentral pigmentary retinal degeneration, whose fundus lesions were bilateral, symmetrical grayish zones with pigments surrounding the macular region. All showed good visual acuity, normal color vision, mild deterioration of scotopic electroretinographic response, normal photopic electroretinographic response, subnormal electrooculogram and paracentral ring scotoma. The fluorescein angiography demonstrated hyperfluorescent dots around the macula. Their family history was noncontributory. The retinal lesions showed only very slow progression.

Adult↗
PubMed1985

[Epidemiologic study by interview on carcinoma in situ of the cervix uteri].

From 1950 to 1979, 1248 patients with cancer in situ of the cervix uteri were treated at the Department of Gynecology, Cancer Institute Hospital, Tokyo. Information was obtained from 585 of these patients by direct interview. Many patients revealed early experience of first sexual intercourse and many had had more than two sexual partners and a large discrepancy between the age at first sexual intercourse and at first marriage. Early experience of first sexual intercourse, marital status and the number of sexual partners all seem to have a relation to the development of cancer in situ.

Adult↗
PubMed1985

[Chronological change in abnormal behavior produced by long-term methamphetamine administration in the rat].

Rats received once daily injections of methamphetamine (MAP; 4 mg/kg/day) intraperitoneally, at most 100 times. Enhanced ambulatory activity by MAP reduced during the long-term administration of MAP. The mean rating score of MAP-induced abnormal behavior, including locomotion, stereotyped behavior, motor inhibition and the response to acoustic stimulation, increased until 56th injection of MAP. But after that, the score tended to decrease mainly because the injected MAP failed to keep the movement of rats reduced under acoustic stimulation. Neither the time course of these rating score nor the decrease in [3H] spiperone binding sites, examined after the injection of MAP 100 times, seemed to develop along with the repeated MAP administration. Thus, the changes in both behavior and [3H] spiperone binding sites produced by repeated MAP would not necessarily indicate the symptoms of MAP-induced psychosis in man, because the susceptibility to psychosis in man increases along with the time of MAP injection. It is presumed that the animal model of psychosis produced by administration of MAP is important not as a model of psychotic symptoms, but as a model of increased susceptibility to psychosis induced by MAP.

Animals↗
PubMed1985

Portal vein or hepatic vein? A curious aberrant vasculature in the liver with idiopathic portal hypertension.

The existence of aberrant vasculatures has been described as one of the characteristic findings in the liver with idiopathic portal hypertension (IPH). In this paper, the morphological features and the genesis of aberrant vasculatures were studied on the basis of autopsy and biopsy materials of IPH and animal experiments. Aberrant vasculatures in IPH livers are characterized as thin-walled vessels located mainly adjacent to the portal tracts and at times in the hepatic lobules. Although some of them are morphologically very similar to hepatic vein branches, they are portal in nature. These aberrant vessels develop in order to compensate for portal circulatory insufficiency due to obliteration of portal vein branches, and play an important role in maintaining an adequate blood supply to the parenchyma. It is predicted that decrease of these intrahepatic collateral vessels is responsible for or related to parenchymal atrophy and deterioration of liver function in the advanced stage of this disease. We regard these vasculatures as characteristic of the intrahepatic portal venous obstruction, particularly with portal hypertension accompanied by increased portal blood flow.

Adult↗
PubMed1985

Circinate choroidal degeneration.

We present a patient whose fundus lesions were bilateral, symmetrical grayish zones with pigments surrounding the macular region. She showed good visual acuity, normal color vision, mild deterioration of scotopic electroretinographic response, normal photopic electroretinographic response, subnormal electrooculogram and paracentral ring scotoma. Fluorescein angiography revealed regional atrophy of the choriocapillaris. The diagnosis of circinate choroidal degeneration was made. We believe that pericentral pigmentary retinal degeneration and circinate choroidal degeneration are distinct entities.

Choroid↗
PubMed1985

[The recent mortality and incidence rate of cancer of the nose, nasal cavities, middle ear and accessory sinuses].

A case-control study was performed on cancer of the nose, nasal cavities, middle ear and accessory sinuses from 1982 through 1984 in Hokkaido. Maxillary sinus cancer accounted for 84% of this cancer in men and 87% in women. Histologically, squamous cell cancer was observed in 91% of the men and 83% of the women. The age-standardized incidence rates of this cancer were 1.3 per 100,000 for men and 0.4 for women. These figures were compared with the age-standardized mortality rates of this cancer for 1975 and 1980 by sex.

Adult↗