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Biomedical subjects

K Ewe

Publications and source records attributed to K Ewe.

At least 145 records · Page 8Linked to original sources

[Manometric study of esophageal involvement in progressive systemic sclerosis (author's transl)].

In 15 patients with progressive systemic sclerosis esophageal function was examined radiologically and by manometry. Only one third of the patients had experienced dysphagia, while radiologically esophageal motility was abnormal in 8 patients (55%) and by manometry even in 11 patients (73%). Therefore the absence of symptoms does not exclude extensive involvement of the esophagus. Furthermore the manometric results indicate that involvement of the esophagus in the edematous-indurative stage of scleroderma should be suspected more frequently than assumed generally on the base of radiological studies alone.

Aged↗

Alteration of esophageal peristalsis by pentagastrin in patients with diffuse esophageal spasm.

Although it has been shown that gastrin and gastric alkalinization affect the lower esophageal sphincter, in vivo studies have not demonstrated a measurable effect of pentagastrin on esophageal peristalsis. In 9 patients with diffuse esophageal spam and in 10 control subjects esophageal peristalsis was recorded before and after pentagastrin infections. Subcutaneous pentagastrin increased peak amplitude significantly more in patients, 31.2 +/- 8.1 mm Hg (mean +/- S.E.M.), than in controls, 12.1 +/- 5.1 mm Hg (P less than 0.02). Max. duration of contraction waves in patients showed a rise of 11.3 +/- 2.7 sec as compared to controls, 1.9 +/- 0.9 sec (P less than 0.01). The effect of pentagastrin on esophageal peristalsis in patients with diffuse esophageal spasm may be explained as denervation supersensitivity.

Carbachol↗