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Biomedical subjects

K Elliott

Publications and source records attributed to K Elliott.

82 records · Page 5Linked to original sources
PubMedDate not supplied

Sensory stimulation in prolonged coma: four single case studies.

Patients diagnosed as being in prolonged coma (vegetative state) in this hospital are routinely treated according to a sensory stimulation protocol. This paper reports an evaluation of the efficacy of this procedure using the comparison of behavioural measures taken immediately prior to and post-stimulation. Four single cases produced significant behavioural changes suggesting increased arousal as a result of stimulation. The results and implications for further evaluation studies are discussed.

Adult↗
PubMedDate not supplied

A prospective audit of hospital-acquired deep vein thrombosis and pulmonary embolism.

The incidence of symptomatic deep vein thrombosis and pulmonary embolism acquired in hospital was studied, and the effectiveness of current thromboprophylaxis was assessed in an open study of 8648 admissions to the Doncaster Royal Infirmary between April and July 1994. On admission, all patients were assessed for their likely risk of thromboembolic problems according to THRIFT criteria. Treatment, prophylaxis, complications and outcome were recorded on discharge. A high risk sub-group was followed up for up to 42 days after discharge. The overall rate of clinically apparent hospital-acquired thromboembolic complications was 0.4% (n = 35). The rate of clinically apparent thromboembolic disease in the high risk group was 2.1% (n = 17). The incidence of thromboembolic problems appeared not to be reduce by prophylaxis apparently even when stratified by risk group. These findings suggest that thromboembolic complications may be less common than would be expected from published literature. Thromboprophylaxis as currently practised within our institution does not seem to affect the incidence of deep vein thrombosis or pulmonary embolism, and these results would appear to argue against a 'blanket' policy for pharmacological thromboprophylaxis.

Adolescent↗
PubMedDate not supplied

Extensive replacement of spinal cord and brainstem by hemangioblastoma in a case of von Hippel-Lindau disease.

We report an extremely unusual case of von Hippel-Lindau disease, characterized by almost total replacement of the spinal cord and most of the medulla by capillary hemangioblastoma (CHB). A 34-year-old female presented 20 years earlier with signs of lower limb weakness. She developed progressive quadriplegia despite multiple surgical attempts to remove separate CHBs from the midthoracic and cervical spinal cord. Spinal cord lesions continued to develop as did multiple cerebellar CHBs. She eventually became respirator-dependent and died following severe upper gastrointestinal hemorrhage. At autopsy there was extensive replacement of spinal cord and medulla by CHB as well as multiple solid and cystic cerebellar tumors. Both kidneys were enlarged and largely replaced by renal cell carcinomas and simple cysts. Additionally she had small pancreatic cysts and microscopic pulmonary hamartomas were observed. There was no evidence of retinal lesions clinically or at autopsy. Light microscopic and immunohistochemical studies of the lesions are presented. The early onset of this disease in a female, with such extensive spinal cord involvement, in addition to other CNS and visceral manifestations of von Hippel-Lindau disease, is unusual and has not been previously reported.

Adult↗