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Biomedical subjects

K Dellagi

Publications and source records attributed to K Dellagi.

At least 163 records · Page 9Linked to original sources
PubMedDate not supplied

[Rearrangement of immunoglobulin genes in alpha heavy chain disease: a criterion of monoclonality].

We have studied the configuration of genes encoding for the heavy and light chains in the tumoral cells of 6 patients affected by alpha heavy chain disease (alpha HCD). The results showed the presence of rearrangement of the alpha heavy chain as well as the kappa light chain genes whereas the lambda genes were in germinal configuration. Thus, these results suggest the presence of a monoclonal compound in the tumoral cells in the alpha HCD.

Adult↗
PubMedDate not supplied

[Scleroma of the upper respiratory tract. Apropos of a case of laryngeal localization].

A case of rhinoscleroma with laryngeal localization is reported. Geographic distribution of this granulomatous disease is discussed. Clinical and paraclinical features are explained. Its tumor-like appearance and local spread arouses suspicion of malignancy but differential diagnosis also includes fungal infections and numerous granulomatous diseases. The classic histopathology consists of large Mikulicz's cells. Treatment is essentially based upon antibiotics.

Adult↗
PubMedDate not supplied

The squash blot technique and the detection of Leishmania major in Phlebotomus papatasi in Tunisia.

This study describes the preliminary applications of the squash blot technique in Tunisia, to detect Leishmania major in naturally infected Phlebotomus papatasi. 309 P. papatasi among 364 female sandflies squashed on to nylon Gene Screen DNA transfer membranes, were identified using the 3.2 kb ribosomal P. papatasi specific DNA probe described by Ready et al. A second hybridization using the Taq1 DNA probe described by Smith et al. (1989) allowed the detection and identification of the parasite in 15 (4.9%) of these P. papatasi specimens. The dissection of P. papatasi females during the same period and from the same biotopes showed an infection rate of 7.9% (9 positives among 113 dissected). The t proportion comparison test indicated that there is no significant statistical difference between the dissection and the squash blot technique for the estimation of infection rates of P. papatasi.

Animals↗