Search PubMed⌕ Search

Biomedical subjects

K C Tan

Publications and source records attributed to K C Tan.

At least 163 records · Page 9Linked to original sources
PubMed1990

Aplasia cutis congenita. A case report and annotation.

Aplasia cutis congenita (ACC) including epidermolysis bullosa (EB) are rare congenital conditions. In ACC there is a localised absence of skin while in EB blistering occurs with a split at the epidermal or dermal level. In the past these 2 conditions have been reported to occur in the same patient. A case of a Gurkha baby girl illustrating just such an entity with severe erosive defects over the head, face, trunk and acral parts of the limbs presenting at birth is reported. There was also widespread blistering over the chest, abdomen and back. The baby died after 3 days from serious complications.

Epidermolysis Bullosa, Junctional↗
PubMed1990

Computer applications in dermatology.

Advances in computer technology both in hardwares and softwares has stimulated the proliferation of the use of computers in dermatology. The computers enable the voluminous medical literature and records to be compiled and accessed readily. Information technology enables dermatologists to conduct literature searches efficiently and helps in the management of patients. The information compiled in the computers as databases together with its capability to handle complex statistical analysis also enables dermatologists and computer scientists to develop expert systems to assist the dermatologist in the diagnosis and prognostication of diseases and to predict disease trends. Computers have also allowed dermatologists to assess visual images objectively, making it possible to study treatment response more accurately.

Artificial Intelligence↗
PubMed1990

Basal cell carcinoma of the head and neck region--a five-year study (1984-88).

Two hundred and seventy-two patients with 292 lesions of basal cell carcinoma of the head and neck region treated at the Department of Plastic Surgery, Singapore General Hospital over a period of five years, were reviewed. Basal cell carcinoma is common in the face, the lesser pigmented mongoloid race of our population and has a higher incidence in the elderly age group. A large number (63%) of the basal cell carcinoma are of the pigmented variety, a very unusual feature. The commonest site of occurrence is the nose (37%). Of the 292 basal cell carcinoma excised, 27 (9%) had tumour involvement of the margins of excision. However, of these 27 cases, only 4 have presented with recurrent tumour. The place of close observation and immediate re-excision of positive margins is discussed. The 4 cases of recurrent basal cell carcinoma involved the nose and lip area, areas with a known higher incidence of recurrence. The results of treatment (98.7% cure rate) of this group are encouraging and compares well with those of other series and using other modalities of treatment. Longer follow-up is required.

Adult↗
PubMed1989

Biliary atresia.

Explore the source record for details and available documents.

Anastomosis, Surgical↗
PubMed1989

Visual displays: the highlighting paradox.

Office computer users view well over a billion displays in a given year. The savings of only a fraction of a second in the time it takes users to process each display can potentially lead to enormous time and cost savings. In recent research investigators have shown that on average subjects are quicker to find a target option in a highlighted display than in a display without highlighting. Paradoxically, in related research other investigators have shown that subjects are slower to find a target in a highlighted display than in a display without highlighting. In an attempt to resolve this paradox, an additional set of experiments was performed. Results from these experiments suggest that in order to determine whether highlighting will be of benefit, one must know the type of highlighting, the level of highlighting validity, and the probability that subjects attend first to the highlighted options.

Adult↗
PubMed1989

Stillbirths--ten years experience at Toa Payoh Hospital.

An analysis of 287 consecutive stillbirths associated with 47,171 deliveries in Toa Payoh Hospital between 1978 and 1987 was undertaken. The incidence of stillbirths was 6.1 +/- 1.26 per 1,000 total births. 149 out of 287 cases (51.9%) had known causes of death. Intrauterine anoxia and congenital malformations are the commonest diagnosis. In contrast, in 48.1% (138/287) of the stillbirths, we were unable to determine the underlying causes because of maceration and a low autopsy rate. Among the 287 stillborn infants, 54% were born prematurely, and 64.2% were born with birth weights of less than 2,500 g. 8.4% of the mothers had a past history of one to three abortions, and 5.6% of the mothers had a past history of one or more stilbirths. This study showed that the stillbirth rate in this hospital has not changed significantly in the last ten years.

Cause of Death↗
PubMed1989

Biliary atresia.

Biliary atresia remains a serious and devastating surgical condition of early childhood. Despite portoenterostomy almost half of these children remain jaundiced and suffer repeated attacks of bacterial cholangitis or variceal haemorrhage. Recently liver transplantation offers fresh hope for these children.

Biliary Atresia↗
PubMed1989

Jejunal free autograft: analysis of complications and their resolution.

Review of 101 patients who underwent 111 free jejunal autografts has demonstrated an absolute procedural failure rate of 13.5 percent. Salvage reconstruction with a second jejunum was successful in six of nine patients and one third-time jejunum was successful, giving an overall salvage rate of 70 percent. There were 33 patients experiencing pharyngocutaneous fistulas, 20 of whom had been previously irradiated. Of these patients, 15 experienced spontaneous closure and 9 others had successful surgical correction. The mortality rate was 5 percent. Eighty-three percent of patients were restored to adequate per oral alimentation. The jejunum, despite its relatively high complication rate, is an excellent method for pharyngoesophageal reconstruction, expeditiously providing return to function for patients with late-stage disease.

Adolescent↗
PubMed1988

Choledochal cyst: a 14-year surgical experience with 36 patients.

The presentation and management of 36 patients with cystic dilatation of the biliary tree seen over a 14-year period is reviewed. There were 28 females and 8 males, a ratio of 3.5:1. The classic triad of jaundice, pain and an abdominal mass was seen in only seven cases. Twelve patients suffered recurrent pancreatitis. There were three cases of variceal haemorrhage from portal hypertension secondary to biliary cirrhosis, and one case of biliary peritonitis from a ruptured cyst. Internal drainage (cystenterostomy) was performed in nine patients but five of these eventually needed cyst excision. Cysts have been excised primarily in the last 21 consecutive patients without mortality. Preliminary external drainage with T tubes was used before cyst resection in three patients who presented with complications of choledochal cysts. Cyst excision and hepaticojejunostomy is now the definitive treatment of choice.

Adolescent↗
PubMed1988

Recurrent pleomorphic salivary adenoma--the relevance of age at first presentation.

All cases of pleomorphic salivary adenoma treated at the West of Scotland Regional Plastic and Oral Surgery Unit, Canniesburn Hospital, over the 10-year period 1974-1983 have been reviewed. Nearly one-fifth of patients were treated for recurrence. These patients presented with their primary tumour at a significantly younger age (p less than 0.001) than those who remained disease-free. Sixteen of 31 who subsequently developed recurrence were under 30 years of age at initial presentation. Of all patients under 30 years of age at first presentation, 42% subsequently developed recurrent diseases.

Adenoma, Pleomorphic↗
PubMed1988

Hepatic artery thrombosis in pediatric liver transplantation.

The incidence of hepatic artery thrombosis was analyzed in a series of 59 consecutive liver transplants performed in 52 children less than 15 years of age at the University of Louvain Medical School, Brussels, from March 1984 to March 1987. This incidence was 17% for the whole series; it was increased in small recipients less than 3 years of age and less than 15 kg (23%) in weight, as well as when the liver was harvested from a small donor less than 15 kg in weight (38%). It was also increased when the donor liver was supplied by more than one artery. This incidence was markedly reduced by arterial revascularization from the aorta, either directly or by interposition of an iliac segment; the reduced-size livers had a much lower incidence of arterial thrombosis (5%) than the whole livers (23%). In the present series, we did not find any argument to support the view that poorly controlled rejection could be implicated in the pathogenesis of arterial thrombosis.

Adolescent↗
PubMed1988

Pediatric liver transplantation: report on 52 patients with a 2-year survival of 86%.

Between March 1984 and March 1987, 59 orthotopic liver transplantations have been performed in 52 children at the Catholic University of Louvain in Brussels. The actuarial survival was 86% +/- 5 up to 3 years of evolution. The most frequent indication has been chronic hepatic insufficiency (43 patients) mainly because of biliary atresia; seven patients were transplanted for acute hepatic insufficiency and only two for liver tumor. Because of important donor/recipient weight discrepancy, a reduced-size liver was used in 20 occasions either for first or second transplant. No difference in the incidence of major complications were seen between whole liver and reduced size liver transplanted children, with the exception of more frequent subhepatic collections in the first and more hepatic artery thrombosis in the second group. Liver tests, clinical rehabilitation, and survival appear to be equal in the two groups.

Child↗