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Biomedical subjects

K Beyreiss

Publications and source records attributed to K Beyreiss.

At least 73 records · Page 4Linked to original sources

[Resorption disorders in children with phenylketonuria].

The usual loading test with D-xylose was carried out repeatedly in infants and toddlers with phenylketonuria. Significantly worse values of xylose resorption were found in comparison with healthy controls independent of the duration of the phenylalanine restricted diet. A further clearing for the matter of malabsorption in phenylketonuria seems to be recommendable with regard to secondary effects of the diet.

Child, Preschool↗

[Problems in the determination of pancreatic enzymes for the quantitative functional diagnosis of the pancreas in children].

Pancreozymin-secretin tests were carried out in children aged from 0,5 till 12 years by means of a two lumen tube of the Salem-Sump-type and a three lumen perfusion tube. For stimulation we used 2 U/kg of the hormones, each from BOOTs-Corp. Amylase was determined with dinitrosalicylic acid, lipase by titration of acidic equivalents after half hour incubation and trypsin and chymotrypsin with TAME and BTEE respectively. We used PEG 4000 as marker and quantified enzymes secretion as well as liquid secretion by it. We got up to 50% lower results by testing with the two lumen tube. If we are laying the perfusion tube we measured an elevation of the two lumen tube. If we are laying the perfusion tube we measured an elevation of the II-hydroxycorticoides. The concentration of the enzymes in the specimines before perfusion on 3 consecutive days fell by 90% on the average. We discussed some problems of the determination of enzymes and performing of the tests by means of the results.

Amylases↗

[Psychomotor development in atrophic infants (author's transl)].

17 former patients with nutritional marasmus due to malabsorption syndromes of various etiology were followed-up at the age of 5 7/12 +/- 2 1/12 years for the assessment of their psychomotor development. As to the intelligence quotient there was no significant difference in comparison with a representative random sample of 200 preschool children. The mean IQ was 92 +/- 20 (n = 17). 2 children were moron (IQ 64 and 61, resp.), one child was imbecile (IQ 46). In two of them familial disposition of debility must be assumed. The deficit in the capability of the psychomotor functions was striking (fine motoricity, designing). 6 children showed mild forms of electroencephalographic deviations from normal (relative frequency 0.35).

Child↗

[Therapeutic problems in the "short-bowel-syndrome" (author's transl)].

The authors report on 6 children with short-bowel-syndrome. The expectancy of life of the patients depends on the mucosal surface of the residual intestine and on the degree of adaption. After removal of larger proportions of the intestine, nutrition should be started parenterally and followed by an early but cautious oral feeding. The administration must be distributed continuously over the day. At first carbohydrates are given as monosaccharides, fats as M. C. T. and proteins as amino acid mixtures. Carrot soup has proved useful as a water-binding substance for the improvement of stool consistency. An anabolic condition of the metabolism should be maintained. Therapy with cholestyramin is indicated in chologenic diarrhoea. Substitution of vitamins, especially vitamin B12 is very important after resection of the ileum.

Amino Acids↗

[Absorption and metabolism of glycerin in the neonatal period. I. Speed of turnover of glycerin during continuous intravenous infusions in newborn infants of various gestational ages and in older infants].

Glycerol was infused intravenously over 2 hours in preterm and term appropriate-for-date and in term small-for-date infants at the age of 12 to 72 hours and 10 to 14 days and in infants at the age of 3 to 8 months. The dosage was 0.25.kg-1.h-1 and 0.5.kg-1.h-1, respectively. Less than 6 per cent of the glycerol injused were recovered in the urine irrespective of the dosage. The total clearance was 9.1 to 14.6 ml.kg-1. min-1 during the first weeks of life with 0.25 g.kg-1.h-1 glycerol irrespective of gestational age and intra-uterine growth retardation; and it rose to 31.8 ml.kg-1.min-1 in older infants. With 0.5.kg-1.h-1 glycerol the total clearance values were lower in all groups. The glucose blood level and the blood lactate concentration as well as the parameters of the acid-base-balance were not significantly influenced by glycerol.

Acid-Base Equilibrium↗