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Biomedical subjects

K Barton

Publications and source records attributed to K Barton.

67 records · Page 4Linked to original sources
PubMedDate not supplied

Chlordiazepoxide metabolite accumulation in liver disease.

Chlordiazepoxide 40mg daily was used to prevent delerium tremens in a 64-year-old female with alcoholic liver disease. After 20 days, the drug was stopped because of the onset of progressive drowsiness. The kinetics of chloridazepoxide were within the predicted range for patients with liver disease, but the elimination half-lives of desmethylchlordiazepoxide and demoxepam were greatly prolonged at 346 hours and 150 hours, respectively. It is suggested that metabolite accumulation may have contributed to the coma, which is an unusual reaction to chlordiazepoxide.

Chlordiazepoxide↗
PubMedDate not supplied

Orthopaedics: patient assessment before surgery.

The potential for pre-admission assessment clinics has been discussed for many years, but only recently have such clinics been developed. This article reviews how one clinic was conceived and developed. The perceived benefits included improved patient care, opportunity for informed choice, reduction in patient cancellation rates and improved utilisation of theatre time.

Humans↗