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Biomedical subjects

K Aigner

Publications and source records attributed to K Aigner.

At least 73 records · Page 4Linked to original sources
PubMed1980

[Complications following thoracic surgery (author's transl)].

From 1968--1977 a total of 2,670 patients with thoracic injury or disease were treated in the Department of General and Thoracic Surgery at the University of Giessen. Of these, 1,185 patients were operated on: 701 lung resections, 371 thoracotomies, and 113 operations on the diaphragm and thoracic wall. Postoperative complications were observed in 16% and 8% died. Frequency and severity of the complications were dependent on the type of surgery and the underlying disease.

Adolescent↗
PubMed1980

[Somatostatin in small intestine fistulas].

Somatostatin (GIF) was administered to a patient with persisting intestinal fistulas. Somatostatin reduced the tryptical activity of the secretions which subsequently subsided.

Adult↗
PubMed1980

[Pneumological findings in workers of chemistry and steel industry (author's transl)].

The pneumological examination of workers of the chemistry and steel industry revealed evident bronchopulmonary findings. The clinical and also the bronchoscopic findings are uncharacteristic. Chest X-ray shows interstitial and alveolar involvement, but in some cases it is normal. Lung function tests are valuable for early diagnosis, especially if both targets of the inhalative irritants, bronchus and alveolus, are respected. The essential loss of function concerns the gaseous interchange caused by bioptically demonstrated persisting, pneumoconiotic fibrosis. As a consequence of this findings in respect to diagnosis there has to be a more critical interpretation of chest X-ray, lung function tests including gaseous interchange analysis, perhaps also biopsy for correct interpretation of uncharacteristic complaints in the case of exposition, and finally also widening of the examinations in cooperation with the industry.

Alloys↗
PubMed1980

[Surgical treatment of lung abnormalities].

Four cases of lung malformations are presented. In this cases symptoms, diagnostic procedures, indications for operation and surgical treatment are discussed. Agenesis and aplasia of lungs do not require surgical treatment. Hypoplasia of the lung, an accessory lung and sequestrations leading to purulent-recurrent infections can be treated by resections.

Adolescent↗
PubMed1975

[Computer experience and further developments in the respiratory function laboratory (author's transl)].

Reported is on satisfactory results obtained with a small-size computer consisting of punching and scanning device, as well as plain writing machine in the respiratory function laboratory. Developed in on- as well as off-line processing by an own technical staff, a diagnostic and teaching program was established for all respiratory function routine methods with the advantages of a large number of cases examined, elimination of sources of error, considerable supply of data and information, automatic documentation and filing, plain writing, interpretation and evaluation of findings. In continuation of such works also the blood gas analysis has been included. These values as the total of disturbances of the pathophysiological acid-base status are considered and interpreted. Clinical correction is forced in this man-machine dialogue by automatic stops of the whole machinery before going on. Subsequently and in addition are computer alveolar-arterial oxygen pressure gradient, venous shunt and oxygen saturation and expressed utilizing the capacity of the small-size computer. Further developments in the respiratory function diagnostic- and teaching program for small-size computers--not too expensive in the building block principle - are intended.

Acid-Base Equilibrium↗
PubMed1975

[An acid-base blood-gas calculator (author's transl)].

A prerequisite for the practical application of the blood-gas values is a calculation of the base excess with regard to the Hb and the interpretation of the acid-base status present. We have provided an aid for the rapid and practicable carrying out of calculations, based on well known nomograms and we think it gives, in principle, a simplification of the method.

Acid-Base Equilibrium↗
PubMedDate not supplied

[Combination chemotherapy and chemoembolization in the treatment of primary inoperable hepatoblastoma].

A 33 months old girl and a 5 months old boy presented with unresectable hepatoblastoma (group III) and were treated with combination chemotherapy using Adriamycin, Cyclophosphamide, Cisplatinum (regimen I) and Adriamycin, Etoposide, Cisplatinum (regimen II). In both patients tumor size and alpha-fetoprotein levels decreased remarkably. Tumor regression was considerably enhanced by selective chemoembolization (Ethibloc, Adriamycin) of the right hepatic artery in one patient. After preoperative chemotherapy hepatoblastomas could be removed surgically. Local recurrence in the older patient was treated again successfully by surgery and chemotherapy. The patients are surviving disease-free 17 and 28 months from diagnosis. The efficacy of the treatment warrants prospective clinical trials in patients with unresectable hepatoblastoma.

Antineoplastic Combined Chemotherapy Protocols↗
PubMedDate not supplied

Isolated extremity perfusion with DTIC. An experimental and clinical study.

Dacarbazine (DTIC) was used for isolated perfusion of extremities in dogs and man. In the animal experiment perfusions with DTIC at dosages up to 100 mg per kg of extremity weight were well tolerated. The concentration of DTIC in the perfusate ranged from 70 to 400 micrograms/ml without evidence for formation of metabolites. Electron microscopy, performed 14 days later, revealed a decrease of glycogen in striated muscle cells. Vascular damage was not observed. Five patients with advanced malignant melanoma or soft tissue sarcoma of the extremities were treated by isolation perfusion with 75 to 133 mg DTIC per kg of extremity at 40 degrees C for 60 minutes. A tumor regression of at least 30% was observed.

Animals↗