[Islet cell adenomas producing hypoglycemia and neuropsychiatric symptoms in a brother and a sister].
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Biomedical subjects
Publications and source records attributed to J Y Goas.
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Meningo-encephalitis due to Candida albicans is frequently iatrogenic in origin and the factors leading to its appearance should be known (immunity disorders and more particularly indiscriminate prescribing of antibiotics). Diagnosis is usually difficult and direct examination of the CSF and culture on special media are necessary in order to demonstrate the presence o yeasts. Recovery is possible with present-day therapy (two out of the three cases reported).
The authors report a case of Campylobacter fetus septicaemia from a cancerous patient. The bacterium was isolated from three blood cultures. The infection characteristics are briefly discussed.
The authors report the clinical and radiological study and the treatment of a fifteen members family (the two parents and their thirteen children) affected with a thoracic outlet syndrome secondary to a cervical rib and or an apophysomegaly of the seventh cervical vertebra. On the fifteen people considered, the father being deceased has not been examined but has an evocative clinical history. The mother has a clinical impairment with a late beginning and no radiological sign. Twelve children have clinical and radiological signs, one has radiological without clinical signs. Three children underwent a surgical treatment, the others only medical treatment. There is no satisfactory correlation between the clinical features and electrical investigations (electromyography, nerve conduction studies) and radiological examinations. The semiology is vascular, neurologic or mixt. Roos test seems more reliable than that of Adson, Calb and Roth, and Saunders. Eight grand-children out of fourty have been examined. Five have clinical and radiological signs, three have casual radiological signs. The radiological impairment of this family contrasts with the normal frequency of cervical anomalies in the population which is 0,12 to 1%. The family impairment of the thoracic outlet syndrome is rarely reported.
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The case of a female patient with longstanding epilepsy is reported. Many problems in achieving a satisfactory therapeutic regimen were encountered. They originated in storage of phenobarbital, which had been prescribed since childhood, interference between phenobarbital, dipropylacetic acid, and phenylhydantoins. Some pharmacokinetic principles are reviewed in the light of this clinical experience.
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