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Biomedical subjects

J Y Goas

Publications and source records attributed to J Y Goas.

At least 37 records · Page 2Linked to original sources

[Meningovascular syphilis. Apropos of 4 cases].

In four cases of stroke, it is only the systematic practice of serologic tests for syphilis that has permitted the true diagnosis and the true treatment. We observed cerebral, brain-stem and medullar infarction and one case of cerebellar haemorrhage. Meningo vascular syphilis is now the most frequent of the central nervous system lesion. Cerebrospinal fluid is always abnormal in active disease. The decrease of cell count is the best control of the treatment that needs high doses of Penicillin G.

Aged↗

[Alcoholic epilepsy. Decrease of tryptophan levels in the blood and cerebrospinal fluid].

The initial, functional stage of alcoholic epilepsy has been attributed to disturbances in neuromediators, including serotonin. Tryptophan, a precursor of serotonin, was assayed in 10 alcoholic patients with epilepsy and in a group of subjects with normal tryptophan metabolism and undisrupted blood-brain barrier. Tryptophan levels were measured in the cerebrospinal fluid and free and total tryptophan levels in plasma, using an automatized continuous flow method. Compared with controls, the alcoholic patients showed a highly significant decrease of all tryptophan fractions.

Adult↗

[Multiple cerebral tuberculomas. X-ray computed tomographic diagnosis and follow-up: a case].

A 31-year-old man who had never left France, rapidly developed right cerebellar signs accompanied by an alteration of his general condition. CT brain scan showed 7 intracerebral tuberculomas, six of which were asymptomatic. The patient was treated with three anti-tuberculous drugs and steroids, and made a good recovery. The CT changes disappeared. CT brain scan should be performed in patients with extra-cerebral tuberculosis and no CSF abnormalities.

Adult↗

[The interest of CSF examinations in the etiological diagnosis of intracranial hypertension (author's transl)].

The authors discuss the case of a 15-year-old girl suffering from intra-cranial hypertension. Neuroradiological examinations do not reveal any obstruction in the cerebral spinal fluid circulation. The CSF cylologic examination was the first to give etiological indications, showing the existence of malignant cells which the cerebral biopsy later enabled us to classify as glioblastoma. This case affords an opportunity to recall the three stages of the diagnosis: first, intra-cranial hypertension; secondly, chronic meningitis; thirdly, cytological difficulties in the examination of CSF in patients having undergone neuro-radiological examinations.

Adolescent↗

[Management of transient ischemic cerebral attacks (author's transl)].

Practitioners should be familiar with the description of transient ischemic attacks (TIA) as 40% are followed more or less rapidly by a stroke. Analysis of the natural history of TIA shows that patients die twice as often from cardiac manifestations of atheroma than from cerebral lesions. This demonstrates the significance of diagnosis and treatment of risk factors. Patients are at increased risk of stroke during the six to twelve months following TIA. Anticoagulants and inhibitors of platelet aggregation seem to reduce this risk. Carotid surgery is indicated only for localized vascular lesions; in other cases surgery increases morbidity. Doppler examination is the best means of detecting cases which need emergency surgical treatment.

Anticoagulants↗

[Familial anomaly of the seventh cervical vertebra. Radio-clinic comparison in a fourteen member family].

We report a fourteen member family presenting with an anomaly of the seventh cervical vertebra. The symptoms associate pain and paresthesias, a C8-D1 syndrome or arterial manifestations. The radiologic lesions noticed are bilateral in twelve cases, either cervical ribs or apophysomegaly of the seventh vertebra's transverse process. There is no correlation between the severity of the clinical impairment and the importance of the radiologic image. We insist on the familial character rarely reported in the literature of an anomaly noticed in radiologic practice.

Adult↗