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Biomedical subjects

J Witte

Publications and source records attributed to J Witte.

At least 91 records · Page 5Linked to original sources
PubMed1990

[Lactic acidosis--recognition and treatment of an important complication of perioperative parenteral nutrition].

We report 5 cases of acute vitamin B-1 induced lactic acidosis in surgical patients receiving parenteral nutrition. In all patients treatment with vitamin B-1 induced a dramatical improvement of clinical findings. 4 patients recovered completely, 1 patient died from already developed irreversible cardiocirculatory failure. These cases underline the need for regular vitamin B-1 substitution in patients with parenteral nutrition and preoperatively in alcoholics and in patients, in whom a sufficient food intake can not be assured.

Acidosis, Lactic↗
PubMed1989

[Bone marrow micrometastases in colorectal cancers].

To date, the detection of individual micrometastases or disseminated tumor cells has not been possible with conventional diagnostic procedures. With the aid of new immunocytochemical investigation, however, histogenetically different cells can now be detected in the bone marrow. The monoclonal antibody, cytokeratin component 18, is most suitable for the detection of micrometastases from colorectal carcinoma. In 22 out of 82 patients with colorectal carcinoma, we were able to detect CK2-positive cells. The incidence of these "micrometastases" is represented as a function of primary tumor size, lymph node involvement, distant metastasis, and degree of malignancy of the tumor, age and sex of the patient, and tumor localization.

Adult↗
PubMed1989

[The academy for surgical postgraduate education and practical continued education of the Professional Society of German Surgeons].

The aim of the academy is to present an up-to-date knowledge of all fields of surgery to young surgeons in the 5th/6th year of education. The main topics are taken from general, trauma, vascular, pediatric, neuro- and heart-surgery. The meetings are held once per year in five different cities in Germany. The second branch of the academy is an annual symposium dealing with five different current events that will be discussed each for half a day. Furthermore there is offered a course for ultrasound and another for endoscopy.

Curriculum↗
PubMed1989

Current status of anti-bradycardial electrotherapy.

A review of the current status of cardiac pacing in the treatment of cardiac bradyarrhythmias is presented. The article describes the indications, haemodynamic principles of differentiated treatment and the technical potential of a new generation of (multi-mode and multi-parameter programmable, rate responsive) devices.

Bradycardia↗
PubMed1989

Results of pacemaker therapy in the German Democratic Republic. Organizational, methodological and technical aspects.

A review of the organizational, methodological and technical aspects of pacemaker therapy in the German Democratic Republic is presented. It underlines the importance of expeditious decentralization of cardiac pacing centres and the role played by an inter-disciplinary working group made up of cardiologists, surgeons and health-care engineers in establishing a uniform therapeutic standard. On the basis of data provided by the nation-wide registry of pacemaker therapy, statistical data on the numbers of pacemaker implantations, patient distribution by age and sex, indications and methods of pacemaker implantation and the types of devices employed are presented. Moreover, the current standard of technical development of pacemaker therapy in the German Democratic Republic is evaluated drawing on an analysis of this country's programme of pacemaker manufacture.

Adolescent↗
PubMed1988

Percutaneous pacemaker lead-transsecting catheter.

We describe the development and successful use of a percutaneous lead-transsection catheter. It was used in two patients in whom removal of chronically implanted atrial pacing leads could not be accomplished by traction.

Cardiac Catheterization↗
PubMed1988

The pacemaker syndrome: a haemodynamic complication of ventricular pacing.

To investigate the pacemaker syndrome (PS) presenting a mixture of signs and symptoms (syncope, presyncope, nausea, dyspnoea, vertigo, loss of physical fitness, congestive heart failure) and related to ventricular pacing, the authors measured cardiac output (CO), peripheral blood pressure (PAP) and peripheral resistance (PR) during continuous atrial and/or ventricular pacing in two groups: patients with and without PS. In both groups a significant decrease in CO was found between atrial and ventricular pacing. A significant difference between the two groups was found in the degree of PAP drop which was significant in the PS group, in the group without PS insignificant. On the other hand, the PR increase at ventricular pacing was in the PS group insignificant, in the symptomless group significant. It is concluded that ventricular pacing causes a CO decrease due to loss of normal atrial transmission. Hypotension in PS patients is connected with an atrial reflex that inhibits normal vascular tone.

Adult↗
PubMed1985

[Chylaskos in lymphangioleiomyomatosis. Peritoneo-venous drainage with Denver shunt].

Chylous ascites, due to a lymphangiomyomatosis and resistant to conservative therapy, occurred in a 30 year-old female. A distinct subjective and clinical improvement could be attained with the aid of a peritoneo-venous anastomosis employing a Denver-Shunt. With the preconditions that the implantation is correct and that it is reliably managed, we regard the Denver-Shunt system as a recommendable approach to the treatment of chylous ascites not controllable by conservative measures.

Adult↗
PubMed1985

[Reconstruction of esophageal passage in functional disorders (achalasia, Zenker diverticulum, spasms)].

Before removing the diverticula (running suture for mucosa, interrupted stitches for the esophageal wall with resorbable material) a myotomy of the upper sphincter (pars inf. of the crycopharyngeal) muscle should be performed to restore the preoperative insufficient relaxation of the upper sphincter. The diffuse spasm shows a normal function of the LES; painful attacks can be treated by calcium antagonists or nitroglycerin. The achalasia can be treated either by endoscopic dilatation or myotomy to reduce the LES-pressure and restore the insufficient relaxation of the LES.

Dilatation↗
PubMed1985

[Computed tomography of esophageal carcinoma. Correlation between computed tomographic and postoperative findings].

Between March, 1980 and January, 1984, computerized tomography (CT) was performed on 110 patients with proven esophageal carcinoma. In 26 patients, information obtained preoperatively by CT was compared with results of intraoperative exploration or histologic examination of resection specimen. Correlation analysis showed that accuracy of CT in assessing actual tumor size and mediastinal or abdominal lymph node involvement is rather limited, while correct results were obtained in between 84 and 100 per cent of patients as far as identification of invasion of adjacent organs is concerned. We thus advocate routine use of CT in the process of preoperative assessment of operability and staging.

Aged↗