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Biomedical subjects

J Wilson

Publications and source records attributed to J Wilson.

At least 1,009 records · Page 56Linked to original sources

Integrated care management.

Some clinicians are at the leading edge of good practice in the introduction of integrated care management (ICM) (Wilson, 1996) based on partnership, quality and driven by performance. The new Government White Paper (Department of Health, 1997) outlines proposals for integrated care with all care planners and providers working collaboratively. A number of health and social care organizations have worked collaboratively to develop care programmes based on patient-centred care. One of the vehicles is multidisciplinary pathways of care (MPCs) which is the risk management tool for monitoring jointly agreed quality and patient outcome criteria from the performance of planning and providing individual patient care. ICM views the multidisciplinary approaches to collaborating care delivery by activity, cost and quality, and using a process approach to problem- and outcome-based care delivery. Involving patients and their carers in determining the process and outcomes of care provides a route to better communication, patient and staff satisfaction and the overall quality of care. This article deals with the use of ICM through the monitoring system of multidisciplinary pathways of care (MPCs) as a tool for minimizing risk and improving the continuous quality improvement of patient care. MPCs are one of the components of ICM which need to incorporate clinical guidelines, protocols, interdisciplinary standards, evidenced-based practice and clinical outcomes which are continuously monitored across all sectors of care.

Analysis of Variance↗

Best practice guidelines.

Best practice guidelines and multidisciplinary pathways of care are becoming an established and essential feature of clinical practice. They can be seen in a wide variety of clinical settings ranging right across the primary, secondary and tertiary health and social care spectrums. The 1997 White Paper places strong emphasis on quality and consistency of care delivery and gives assurances of performance measurements, integrated care (Wilson, 1996) and clinical governance. It suggests making healthcare delivery against national standards a local responsibility and quality of care the driving force for decision making at every level of the service to ensure excellence for patients no matter where the care is provided. A number of controversial issues surround the use of guidelines. Some argue that they are a fetter on clinical discretion, clinical freedom and can lead to the practice of 'cookbook medicine'. Others maintain that they are an essential aid to providing safe and appropriate medical and nursing care.

Benchmarking↗

Health and safety in the NHS.

With the increase in the number of employer liability claims there is a need for all healthcare organizations to demonstrate that they can meet the requirements of NHS health and safety issues (HSG(97)6). The NHS is the second biggest employer in Europe and is currently paying out in excess of 30 million Pounds on employer liability cases. Health and safety strategy should aim to remedy the current situation, enabling healthcare providers to meet legal and common law duties of care. A clear and focused programme for action can be established, building on the current momentum for change and development.

Employment↗

Lifelong ambitions.

Explore the source record for details and available documents.

Adaptation, Psychological↗

Childbearing within the prison system.

The immediate pre and postnatal periods are a time of high anxiety for most women, but for those living in prisons, the stressors can be multiplied. Deprived social backgrounds, inconsistent family contact, isolation, poor physical and mental health, and the probability that the baby will be put into care are some of the problems such women face. This article describes the provision of health care generally for women in prison, then examines the particular problems faced by those who are pregnant.

Female↗

Public health inspectors in restaurants: what they do and why.

This report identifies strategies used by public health inspectors in the Central West Region of Ontario during restaurant inspections, based on and comparing the perceptions of inspectors, their managers, and restaurant operators. Factors influencing the choice of strategies are reviewed, putting into perspective the importance of manager and policy expectations relative to other influences experienced by inspectors in the field. The need to set pragmatic and reality-tested criteria and objectives for a HACCP-based inspection protocol is discussed.

Facility Regulation and Control↗

Efficacy of narasin in the prevention of necrotic enteritis in broiler chickens.

The efficacy of narasin in the control of necrotic enteritis (NE) was investigated in a floor pen study of 2000 broiler chickens using a Clostridium perfringens feed inoculum challenge model. Treatments were 1) nonmedicated, nonchallenged; 2) nonmedicated, challenged; 3) narasin, nonchallenged; 4) narasin, challenged. Narasin was administered at 70 ppm in the feed from day 0 to trial termination on day 41. Challenge inoculum contained approximately 1 x 10(8) colony-forming units CP/ml and was administered from day 14 to day 16. In the unmedicated groups, challenged birds had significantly (P < 0.05) lower mean body weight and reduced feed efficiency at day 21 and significantly (P < 0.01) higher cumulative NE mortality at day 41 compared with unchallenged. Similarly, among unmedicated birds, those challenged had a significantly (P < 0.01) higher mean NE score on day 17 and significantly (P < 0.05) higher mean huddling scores on days 15-17 than unchallenged. Among challenged birds, those fed narasin had significantly (P < 0.05) higher mean body weight and improved feed efficiency at days 21 and 41 and significantly (P < 0.01) lower cumulative NE mortality at day 41 than unmedicated. Similarly, among challenged birds, those receiving narasin had a lower mean NE score on day 17 (P > 0.05) and significantly (P < 0.05) lower huddling scores on days 16 and 17 than unmedicated. Coccidiosis lesion scores were zero for birds euthanatized from all treatment groups on day 17, suggesting that the beneficial effects of narasin were not due to prevention of coccidiosis. This study thus provides evidence that narasin is effective in the prevention of necrotic enteritis in broiler chickens.

Animal Feed↗

HLA and multiple myeloma among black and white men: evidence of a genetic association.

To evaluate the possibility that genetic factors contribute to the excess rates of multiple myeloma among blacks, serological typing of human leukocyte antigens (HLA) was conducted for black and white male patients and controls who participated in a large population-based case-control interview study. Forty-six black cases, 88 black controls, 85 white cases, and 122 white controls were typed for the Class I antigens (HLA-A, -B, -C) and for the Class II antigens (HLA-DR, HLA-DQ). Black cases had significantly higher gene frequencies than black controls for Bw65, Cw2, and DRw14, while white cases had higher gene frequencies than white controls for A3 and Cw2 and blanks at the DR and DQ loci. Further analysis of the association between Cw2 and multiple myeloma revealed relative risks of 5.7 (95% confidence interval = 1.5-26.6) and 2.6 (95% confidence interval = 1.0-7.2) for blacks and whites, respectively. The frequency of Cw2 in black and white controls was similar. These findings suggest that the Cw2 allele enhances the risk of myeloma in blacks and whites but do not explain the higher incidence of this cancer among blacks. The study also suggests that undefined DQ antigens may play an etiological role, supporting the need for further research into the immunogenetic determinants of myeloma.

Adult↗

In vitro loss of alcohol from tissue conditioners.

The rate of alcohol loss from two tissue conditioners was investigated by applying them to complete denture record bases and immersing them in water in a sealed container. Samples were taken regularly and analysed by gas chromatography. The alcohol was found to leach out much more quickly than expected with the greatest loss occurring in the first 12 hours and peaking at approximately 60 hours.

Acrylic Resins↗

Should PAF inhalation challenge be used as an experimental model of bronchial hyperresponsiveness in man?

Present evidence suggests that PAF-induced bronchial hyperresponsiveness (BHR) is a variable phenomenon in man. Even in the responders, the magnitude of change is small and the response is poorly reproducible. Endobronchial biopsy and bronchial lavage studies following inhaled PAF did not show any increase in the number of activation of eosinophils, which are pivotal in the pathogenesis of BHR. Unless and until the characteristics of responders are identifiable, PAF inhalation challenge should not be used as a human model of BHR.

Biopsy↗