Biomedical subjects
Publications and source records attributed to J W Weigel.
Fifty-seven patients with germinal cell carcinoma of the testis were evaluated routinely, with the addition of a supraclavicular node biopsy as a final staging procedure. Five patients showed more extensive disease with the addition of this staging modality.
Pelvic lymphadenectomy as a staging procedure in clinically apparent prostatic adenocarcinoma has long been recognized and its value appreciated. Twenty-three recent cases from the University of Colorado of clinically unapparent carcinoma of the prostate were studied with this modality, 5 Stage A1 and 18 Stage A2 tumors. Four of the 18 Stage A2 tumors but none of the A1 lesions after negative staging procedures revealed metastatic disease to the pelvic lymph nodes. Our experience indicated this modality should be employed in selected cases of incidental adenocarcinoma of the prostate.
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A case of an ectopic ureter entering a seminal vesicle cyst and associated with ipsilateral renal agenesis is presented. The differential diagnosis and the embryological explanation of the anomaly are considered.
Vagal hypotension can occur after percutaneous biopsy and be misdiagnosed as hypovolemia due to hemorrhage. Inappropriate exploratory surgery and death have resulted. Increased vagal tone or massive discharge is characterized by hypotension with bradycardia or lack of tachycardia and can occur after many stimuli including contrast medium injection, anxiety, and needle insertion. Vagal reactions can be mild and self-limited, but can also progress to cardiac arrest. Atropine 0.6 to 0.8 mg intramuscularly or intravenously in increments up to 3 mg has been recommended for prompt treatment. Volume expansion is adjunctive.