Search PubMed⌕ Search

Biomedical subjects

J W Ferguson

Publications and source records attributed to J W Ferguson.

At least 55 records · Page 3Linked to original sources

Ultrastructural examination of experimentally induced premalignant lesions.

Lesions induced in hamster cheek pouch using dimethylbenz(alpha)anthracene were studied by transmission electron microscopy and compared with normal tissue. Features regarded as suggestive of progression towards malignancy were: increased numbers of membrane-bound vesicles in basal cells, gaps in the lamina densa associated with widening of the lamina lucida and an irregular epithelial-connective tissue junction, the presence of cerebriform cells and frequent close association of 2 or more intra-epithelial cells (lymphocytes, cerebriform cells, Langerhans cells).

9,10-Dimethyl-1,2-benzanthracene↗

Clinical presentation and final diagnosis of patients referred to a temporomandibular joint clinic.

The clinical presentation and final diagnosis of 182 consecutive patients referred to the Temporomandibular Joint Clinic at the University of Otago School of Dentistry over a 12-month period were reviewed. The definitive diagnosis utilised a classification based upon accepted pathological concepts. Thirty-six percent of patients had internal derangement of the TMJ, 33 percent had joint overload, 12 percent had an acute muscle disorder, 12 percent had degenerative joint disease, and 7 percent had other conditions including ENT disorders and pulpitis. Only six percent of patients underwent treatment involving occlusal modification or TMJ surgery. The remainder received a variety of conservative treatments confirming the widely held view that the majority of patients with a TMJ disorder can be managed with a variety of reversible therapeutic methods.

Adolescent↗

Fractures of the facial bones in the Otago region 1979-1985.

The aetiology, type, distribution, and treatment of fractures of the facial bones is described in the 484 patients with such injuries treated at Dunedin Hospital during the period 1979-1985. The mean annual rate was 51.7 per 100,000. The rate of facial bone fractures has remained relatively constant over a 32-year period in the Otago area. Interpersonal violence is now the most common cause of these injuries. Fractures of the zygomatic complex and fractures of the mandible remain the most common facial fractures. There is an increasing trend towards the use of direct internal fixation for fractures that require treatment.

Adolescent↗

Management of the unerupted maxillary canine.

In orthodontic practice, many patients present with unerupted and impacted maxillary canine teeth. The clinical outcome is frequently compromised by a failure to diagnose the problem at the appropriate age. This article reviews the development of the maxillary canine, the assessment of normal and abnormal eruptive paths and the options for treatment, with particular emphasis on interceptive measures.

Child↗

Parotid gland biopsy for investigation of xerostomia.

A technique is described for biopsy of the parotid salivary gland under local anaesthesia, which has been undertaken for a series of 59 patients who presented with suspected inflammatory exocrinopathy. The procedure is reliable and is associated with negligible postoperative discomfort. The advantages of the technique suggest that parotid gland biopsy is an acceptable alternative to conventional lower lip biopsy of minor salivary glands in the investigation of xerostomia.

Adolescent↗

Torque-in-base: another straight-wire myth?

The theoretical inaccuracies of straight-wire systems which incorporate torque in the bracket face are discussed, with the conclusion that this variation from the original design is unlikely to be of any practical significance.

Dental Stress Analysis↗

Lateral displacement of the intact mandibular condyle. Review of literature and report of case with associated facial nerve palsy.

A rare injury is described, in which symphyseal fracture of the mandible was associated with lateral displacement of the intact mandibular condyle into the temporal fossa and damage to the ipsilateral facial nerve with unilateral facial paralysis. Management of the injury was associated with an episode of acute laryngeal obstruction, necessitating emergency tracheostomy.

Adult↗

An investigation of the polymerization of orthodontic adhesives by the transillumination of tooth tissue.

Prepared samples of light-activated composite were cured by transillumination of tooth tissue in healthy volunteers. Positioning of the samples and the direction of illumination was designed to simulate curing during direct bonding. The effectiveness of curing was investigated by determination of surface microhardness. The degree of polymerization of the specimens cured by transillumination was found to be reduced compared to the control samples cured by direct exposure to the light source.

Adult↗

Multistrand wire retainers: an indirect technique.

A method is described for bonding multistrand retainers indirectly, using a silicone locating splint and visible light curing adhesive. This technique permits construction of the retainer in the laboratory and eliminates the problem of positioning flexible wires in the mouth.

Composite Resins↗

Sebaceous cell adenoma. Rare intra-oral occurrence of a tumour which is a frequent marker of Torre's syndrome.

A case of sebaceous cell adenoma of the buccal mucosa in a 65-yr-old woman is described. The patient exhibited no manifestations of Torre's syndrome (cutaneous sebaceous neoplasms and visceral carcinomas). Only four sebaceous adenomas of the oral mucosa have been previously reported. The literature on neoplasms of sebaceous glands and Torre's syndrome is reviewed. The tumour had not recurred 18 months after surgical excision.

Adenoma↗

Mandibular vascular leiomyoma.

A 54-year-old man had a symptomless swelling on the buccal aspect of the right mandibular molar area, this was associated with a multilocular radiolucency. Histologic and ultrastructural examination of the lesion revealed a vascular leiomyoma. This is only the fourth intrabony leiomyoma of the jaws to be reported.

Diagnosis, Differential↗