Pulmonary hemorrhage in lupus erythematosus without evidence of an immunologic cause.
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Biomedical subjects
Publications and source records attributed to J Vidal.
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The development of dysplasia of the hip in cerebral palsy has been studied in 292 hips in children. The rate of migration of the hip has been defined, and gave a very early indication of the prognosis for the dysplasia. A close relationship was also found between the early radiographic changes and the functional locomotor anatomy. By reviewing the initial radiographs the need for early treatment and its adaptation to the future locomotor potential of the child can be assessed. Treatment is usually by musculotendinous releases and is especially effective in early recentering of the femoral head, but this method is ineffective in correcting bone dysplasia, particularly acetabular obliquity, which starts at around the age of 30 months. It is preferable to anticipate its development by early tenotomies which are much better tolerated than pelvic osteotomy in spastic children.
This study is a retrospective review of 221 patients with untreated idiopathic thoracic and thoracolumbar scoliosis that were observed from the first months of life until maturity. There are three stages in the evolution of these curves: a single main period of progression, a secondary period of progression, and a stable period. The chronology of these different periods varies. In "infantile scoliosis," the main period of accelerated increase of the curve occurs prior to 6 years of age. In "juvenile-puberal scoliosis," it occurs from 6 years of age to the first stages of puberty, and in "puberal scoliosis," the main increase occurs during puberty or adolescence. The prognosis of the scoliosis can be established at any age based on different parameters, such as the specific angle of rotation from birth to 6 years of age, the torsion angle from 6 years of age to P2, and the Cobb angle after puberty.
A non-heme iron containing protein which bears an antigenic similarity to ferredoxin from spinach leaves (Spinacia oleracea L.) has been identified in extracts prepared from young roots of maize (Zea mays L., hybrid W64A x W182E). The ferredoxin-like root electron carrier could substitute for ferredoxin in a cytochrome c reduction system in which pyridine nucleotide (NADPH) reduces the root electron carrier in a reaction catalyzed by ferredoxin-NADP(+) reductase (EC 1.6.7.1) from spinach leaves. However, the root electron carrier did not mediate the photoreduction of NADP(+) in an illuminated reconstituted chloroplast system.A pyridine nucleotide reductase which shares identical immunological determinants with the ferredoxin-NADP(+) reductase from spinach leaves has also been characterized from maize roots. Root pyridine nucleotide reductase mediated the transfer of electrons from either NADPH or NADH to cytochrome c via ferredoxin or the root electron carrier. Under chemical reducing conditions with sodium dithionite and bicarbonate, the ferredoxin-like root electron carrier served as an electron carrier for the ferredoxin-requiring glutamate synthase (EC 1.4.7.1) and nitrite reductase (EC 1.7.7.1) obtained from maize roots or leaves. In the presence of root pyridine nucleotide reductase and root electron carrier, either NADPH or NADH served as the primary electron donor for glutamate synthesis in extracts from maize roots or leaves. The electron transport system originating with NADH or NADPH, was, however, not able to mediate the reduction of NO(2) (-) to NH(3).
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The OFDS and kidney polycystic disease is a rare association. Only 7 cases we have been able to find in several references. A new female case with hypertension is reported.
The results of the study of 51 patients bearing a Milwaukee corset indicate that they present a mechanical and irritative dermatitis caused by the personal predisposition, the action of the plastic material and the occlusion and humidity produced between skin surface and the corset. The authors suggest the name Occlusive Dermatitis Syndrom for this cases as a subtype of Mechanical Irritative Dermatitis.
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One hundred and fifty eight children with an unbalanced pelvis were reviewed. All suffered from cerebral palsy and were treated by tenotomy of the adductor muscles. The aims were: 1 - To improve the position of the femoral head. For this purpose, the best effects were obtained before the age of 4 so that acetabular dysplasia was prevented and the need for pelvic osteotomy, which is often hazardous in this type of patient, avoided. 2 - To achieve better balance of the pelvic girdle. Adductor tenotomy was often associated with tenotomy of the ilio-tibial tract or with division of the costo-iliac or ilio-lumbar muscles with posterior radiculotomies.
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The authors have studied standard radiographs of 200 patients with lumbosacral spondylolisthesis, 52 of whom had been treated operatively. The radiographic technique is described. It allows measurement of pelvic retroversion and its influence on the appearance of slipping. The shape of the sacrum is not a consequence of the position of the pelvis but can alter during growth. Trunk imbalance may lead to increased stress with fracture of the pars interarticularis. Observation of these features makes it possible to follow the development of the deformity and to adopt appropriate treatment.
The authors describe a new type of intramedullary nail used mainly in the femur and or tibia. This nail can be locked by the provision of holes into which screws can be driven transversely. The technique of insertion is described and the use of ancillary devices. The advantages are that weight-bearing can be commenced early even in comminuted fractures. The method includes open reduction of the fracture and allows some compression of the fracture site. The results of a biomechanical study are given. One hundred and forty six patients have been operated on with only 2 non-unions. The authors consider that their method is superior to plating and can be applied in cases that could not be fixed by conventional nails.
External fixation is a method of immobilization that uses percutaneous pins placed in bone and linked with external connectors. The concept of external fixation appears in works of Malgaigne from the mid-19th century. Since Malgaigne's invention many other external fixation systems have been introduced, and external fixation is currently a standard method for treating fractures.
There are three phases in the treatment of open fractures and infected pseudarthroses by the Hoffmann external fixator. During the initial phase a careful surgical debridement is performed in the bony tissues, and the external fixator is applied in a manner appropriate to the type and level of the lesion site (double- or triple-frame mounting; additional anchorages; neutralization, compression, or distraction; ligamentotaxis). During the intermediate phase both the nursing of the patient and care of the apparatus are critical for the avoidance of complications; it is during this period that granulation tissue must develop and bone infections must be controlled. In the final phase the loss of osseous substance must be treated by various means (regular tightening of the external fixator; Papineau's technique; intertibiofibular graft; free microvascular bone transplantation technique.
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