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Biomedical subjects

J Valk

Publications and source records attributed to J Valk.

At least 163 records · Page 9Linked to original sources

MRI of normal or cancerous laryngeal cartilages: histopathologic correlation.

MRI appearances of laryngeal cartilages, normal or invaded by cancer, are still relatively unfamiliar to most clinicians. Twelve primary laryngeal tumors out of a series of 65 patients which have been investigated by MRI were examined postoperatively by macroscopic and microscopic sectioning of the surgical specimens. Images were obtained with a 0.6 Tesla superconductive system using a solenoid surface coil. The authors emphasize the value of a combined use of T1-weighted and balanced (relatively T2-weighted images with still T1-characteristics) Spin Echo images. T1-weighted images permit differentiation between pathological and normal bone marrow. Balanced images allow separation between nonossified cartilage and tumor tissue. MRI is an additional tool in the diagnostic workup of cartilage invasion by tumor.

Aged↗

Histiocytic sarcoma of the brain in childhood.

CT-scan findings of the brain in two children with true histiocytic sarcoma are described as well as their changes during therapy. Clinical features and differential diagnosis on CT-scan examination are discussed. Follow-up CT-scan during therapy is of value as an indicator of the response to therapy and possibly the long term prognosis.

Brain Abscess↗

Magnetic resonance imaging of cardiac anatomy. A standard procedure.

A standard procedure was developed allowing study of cardiac anatomy with electrocardiographically gated MRI, using alteration of a single gradient angle of the imaging plane combined with patient rotation. This resulted in projections of the heart through its anatomical axes. The obtained images allow correlation with 2D-echocardiography and left ventriculography.

Adult↗

Sonography of the postoperative brain: a report on 2 years of experience.

Thirty-seven patients were examined by post-operative high resolution real-time ultrasound over a period of 2 years. Useful data were obtained in all cases but the quality of information obtained was directly related to the size of the cranial window. In each patient, the first sonogram was performed during the 10th to 12th postoperative day to assess ventricular size and midline shift and any fluid collections present. This initial sonogram then served as a baseline study for further follow-up. Subsequent sonograms provided different information about tumor response to chemotherapy and/or irradiation, information not readily obtained by computed tomography.

Adult↗

Further experience with ultrasound examinations in the postoperative brain.

Ultrasound examinations (US) of the brain are possible in the presence of an acoustic window in the skull, either after craniotomy or through an open fontanelle. In this study 19 children were examined, 11 via a suboccipital craniectomy; 9 cases were examined more than once. Via this suboccipital route most of the contents of the posterior fossa, the third and lateral ventricles could be made visible. In two patients with a temporal or parietal craniotomy the involved hemisphere could be visualized. Six patients were examined via the open fontanelle after insertion of a ventriculoperitoneal shunt (VPS). In three of these cases the examination was undertaken to evaluate also a posterior fossa cyst. The findings were compared with CT if the findings were equivocal.

Adolescent↗

The role of CT and NMRI in neurosurgical diagnosis.

A brief survey is given of the state of art of NMRI in neurosurgical diagnosis and its advantages and disadvantages in comparison to CT scanning are discussed. Specificity and sensitivity of these methods are also considered.

Brain↗

Computed tomography: a mandatory investigational procedure for the T-staging of advanced laryngeal cancer.

Eighteen patients underwent computed tomography (CT) prior to total laryngectomy. In order to assess the accuracy of CT scanning in the evaluation of carcinoma of the larynx, CT scans were prospectively interpreted and the extent of the tumour was recorded. The tumour extent was evaluated on whole-mount histologic sections of the laryngeal specimens, prepared in the horizontal plane, similar to the CT scan. The results were compared to assess the ability of CT to identify tumour infiltration in the horizontal plane accurately. Based on these findings it is clear that CT has its influence on the T-staging and on the choice of treatment of laryngeal cancer, i.e. radiotherapy versus surgery.

Carcinoma↗

Rapid spontaneous resolution of an acute subdural hematoma.

A patient is reported who had spontaneous resolution of an acute traumatic subdural hematoma within 6 hours. In this period, clinical signs improved and computed tomography suggested disappearance of the hematoma. Magnetic resonance imaging demonstrated no real disappearance, but rather a redistribution of the blood. A rapid resolution like this has not been observed previously in the natural history of acute subdural hematoma.

Acute Disease↗

Iohexol 240 mgr I/ml and metrizamide 240 mgr I/ml in lumbar myelography. Report from a randomized double blind study.

A parallel, double blind, randomized study, comparing iohexol 240 mg I/ml and metrizamide 240 mg I/ml in lumbar myelography was carried out. Fifty patients were admitted to the study, and 1 patient was excluded after entry. Of the 49 patients included, 28 were males and 21 females, aged between 18 and 72 years. A dose of 10.5 ml of contrast medium was administered. A detailed neurological examination, and measurement of blood pressure and heart rate were performed before and 24 h after myelography. EEG was recorded in 37 patients. All patients were observed for adverse reactions for 48 h. Adverse reactions were reported in 14 of 26 patients examined with iohexol, and in 13 of 23 patients examined with metrizamide. EEG changes were observed in 7 patients examined with metrizamide, no changes were observed in patients examined with iohexol. The image quality was judged good or excellent in all cases, with the upper level of contrast medium brought to the level of L1 in the majority of cases.

Adolescent↗