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Biomedical subjects

J Valentin

Publications and source records attributed to J Valentin.

At least 55 records · Page 3Linked to original sources
PubMed1975

Interpretation of data obtained with recombination-defective meiotic mutants.

According to probability laws, additive interaction between factors influencing recombination frequency suggests that the factors affect the same event. This analysis, applied to Carpenter and Sandler's (1974) data, permits separation of different sequential events during establishment of preconditions for exchange. The validity of another mathematical model for meiotic mutant characterization, suggested by those authors, is discussed.

Drosophila melanogaster↗
PubMedDate not supplied

Self-treatment of female external genital warts with 0.5% podophyllotoxin cream (Condyline) vs weekly applications of 20% podophyllin solution.

Sixty women with genital warts were randomly allocated to treatment with either weekly application of 20% podophyllin solution or self-treatment with 0.5% podophyllotoxin cream twice daily for three days in weekly intervals. After a maximum of 4 treatment cycles a final assessment was carried out after 3 months. Primary clearance after termination of treatment was 82% for podophyllotoxin and 59% for podophyllin solution. After excluding relapses at the 3-month follow-up, final clearance for podophyllotoxin (71%) was significantly better (P < 0.05) than that for podophyllin solution (48%). The total frequency of warts eradicated was 94% with podophyllotoxin and 74% with podophyllin solution (P < 0.001). Local adverse effects were generally mild or moderate. Podophyllotoxin cream provides a mode of easy application for women with external genital warts and had in this study a significantly better effect than podophyllin solution.

Administration, Cutaneous↗