Smallpox outbreak and vaccination problems in Stockholm, Sweden 1963. II. Case histories.
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Biomedical subjects
Publications and source records attributed to J Ursing.
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A pigment-producing strain of Serratia rubidaea was isolated from two consecutive cultures from a sponge of silastic foam used as a dressing for chronic crural ulcers. The bacterium caused a red discolouration of the sponge and the surrounding part of the leg. The silastic sponge creates a new type of environment for microorganisms. The growth of previously rare bacteria such as S. rubidaea may be favoured by conditions within the sponge.
Bacteriological filtrates of three strains of Pseudomonas aeruginosa were compared with respect to inhibitory effect on ciliary movements and a quantitative difference was established between them. The cilia inhibitory effect was strictly concentration-dependent and was resistant to heating. The ciliotoxic effect disappeared from filtrates after chloroform extraction. The chloroform-extracted sediment ws dissolved in physiological saline and the solution revealed an inhibitory effect on cilia. Involvement of endotoxin is not probable, since E. coli endotoxin in a high concentration was not toxic. Partially purified Pseudomonas aeruginosa phenazine pigment as well as haemolysin inhibited ciliary activity and the effect was standardized in the present experimental system.