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Biomedical subjects

J Svejda

Publications and source records attributed to J Svejda.

At least 55 records · Page 3Linked to original sources
PubMed1979

Disseminated intravascular coagulation associated with toxic epidermal necrolysis (Lyell's syndrome).

Evidence of disseminated intravascular coagulation was recorded in eight patients with toxic epidermal necrolysis (TEN)--Lyell's syndrome. Patients were treated with low doses of heparin in combination with the usual treatment of TEN, i.e. maintenance of fluid and electrolyte balance, systemic corticosteroids, antibiotics and aseptic dressings, in the Intensive Care Unit environment. It is suggested that the alteration of haemostasis and inter-related biological systems, such as activation of components of complement, kinins and immunoglobulins, may affect the outcome of TEN.

Adult↗
PubMed1979

[The human dental pulp as viewed through a scanning electron microscope (author's transl)].

The human dental pulp was examined using a scanning electron microscope. The odontoblasts are pear-shaped and have a fine-grain surface structure. Tomes' process divides into fine branches before entering the predentin. Very few fibroblasts were found. These had stronger cell processes at the two terminal poles. Adhering to their surfaces were fine fibers. Collagenous and nerve fibers could not be accurately identified in the rich fibrillary network of the pulp. Stronger nerve fasciculi were readily observable through longitudinal sulci. Thinner fibers were seen to spread out in branches from some nerve bundles. The capillaries were observed to be surrounded by a sheath of fine fibrils.

Capillaries↗
PubMed1979

Histologic changes in the human skin melanoma after intratumorous treatment with BCG.

Twenty six patients with malignant skin melanomas were treated with an intratumorous injection of 0.1 ml BCG applicated in certain time intervals. Histologic changes in tumor tissue starting with dystrophy and necrosis of the cells and ending with the formation of a granular tissue replacing the tumor are described. In one case the untreated satellite localized 2 cm from the injected tumor disappeared. The results indicate that the reaction of the cells on the applicated vaccine varied. In some tumors dystrophic changes and necroses were very large, in others they were of a lesser extent, but in all the process ended with the formation of a granular tissue. The mechanism of the action of BCG is discussed. For the time being, it seems that the intratumorous application of BCG is a useful adjuvant therapy.

BCG Vaccine↗
PubMed1978

Cytology in the diagnosis of malignant melanoma.

Some cytologic criteria useful for routine examinations in the diagnosis of malignant melanoma are reported and the diagnostic value of the pre-operatory cytologic smears is also emphasized.

Biopsy↗
PubMed1978

Scanning electron microscopic examination of root after apicoectomy.

The scanning electron microscope was used to examine resected areas of eight roots of human teeth extracted after long intervals following surgical procedures. Some resorption lacunae were observed in the areas with protuberances of newly formed cementum. In the lacunae, honeycomb-like structures were found. On the resected surface, residues of ligaments and periodontal fibers, and in one of the specimens dentinal tubules with odontoblastic processes protruding above the surface were present.

Apicoectomy↗
PubMed1978

[Root canal filling after apicoectomy, as seen on the scanning electron microscope].

The radiologically controled apicectomy shows frequently unsuccessful results. In histological examinations of the root apex area after apicectomy chronic inflammation is regularly seen even in negative radiologic findings. Examination of the most frequently used root filling material (zincoxyphosphate with guttapercha point) by scanning electron microscopy shows a porous surface and between the canal wall and the root filling material there appears regularly a deep groove as no contact is achieved. The rough surface structure, the chemical composition and the loose contact of the components in this area are considered irritative factors and reasons of failure in treatment.

Apicoectomy↗