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Biomedical subjects

J Stines

Publications and source records attributed to J Stines.

At least 37 records · Page 2Linked to original sources
PubMed1995

[Pharyngolaryngeal tumors: spiral X-ray computed tomography with 3-dimensional reconstruction].

Spiral CT allows the exploration of the whole larynx and hypopharynx in 30 seconds. This is a good adjustment between the technique and the organ. Performed on 15 patients during a 30 seconds' Valsalva maneuver, the exploration yields results from good to excellent. In two cases, conventional and helical CT are compared. The limitation of mA is not a drawback in such a thin region and there is no shift of organ or lesion between two scans, because the whole range is scanned in a single breathhold. 3D display of larynx and pharynx can be performed with some advantage, especially easiness of presentation for surgeon. They help topographic analysis and make correlation between endoscopic views and axial scans. They could be useful for surgical simulation and 3D photon treatment plannings.

Feasibility Studies↗
PubMed1994

[Diagnosis and staging of colorectal cancers].

Early colorectal cancer produces no symptom, thus justifying efforts at detection in screening programs. Symptoms are usually secondary to obstruction, local invasion, perforation or bleeding. Any fecal bleeding must be investigated to rule out a colorectal cancer. The initial imaging study to identify a colorectal cancer is often colonoscopy, which is frequently supplemented with a double contrast barium enema. Once the presence of cancer is histologically proven, the preoperative evaluation includes detection of hepatic and extrahepatic spread, especially with ultrasound and CT scan. Endorectal ultrasonography has been shown to be a significant advance for staging rectal cancer. It provides the best staging in selecting patients for preservation of sphincter function and for adjuvant therapies. The most useful prognostic factors in tumors without distant metastases are the depth of tumor extension, the number of positive lymph nodes and the histologic grade. Preoperative CEA level, vascular invasion and ploidy are also important prognostic factors.

Colorectal Neoplasms↗
PubMed1989

[Conservative treatment of breast cancer. Carcinologic and cosmetic results of combination quadrantectomy and irradiation at the Centre Alexis-Vautrin].

We studied the association of quadrantectomy and irradiation in 238 patients with a breast carcinoma treated from 1974 to 1984 in the Alexis-Vautrin Center. Five and ten year survival rate are respectively 89 and 77%. Local relapse rate at five and ten year are 2, and 9%. Local relapse rate is correlated with a young age, a high tumor grade and an internal site of tumor. We studied the cosmetic and functional results and compared objective results according to subjective self-evaluation by the patients.

Adenocarcinoma↗
PubMed1988

[Natural history and development of bone metastasis. Apropos of 429 cases].

The records of 429 patients seen at the Centre Alexis-Vautrin in 1979 and 1980 with bony metastases were retrospectively reviewed to assess their natural history and survival. Breast was the location of primary lesion in 140 patients (32.6%), lung in 95 patients (22.1%) and prostate in 33 patients (7.7%). The primary tumor was of unknown origin in 42 cases (10.9%). The median survival from time of diagnosis was 5 months. Two and 5-year survival rates were 17.5 and 5.1% respectively. According to the nature of the primary tumor, 2 and 5-year survival periods for bony metastases were 36.4 and 7.9% in breast cancer, 33.3 and 15.2% in prostatic cancer, 4.3 and 2.1% in metastases of unknown origin, 2.1 and 0% in pulmonary carcinoma. Multivariate analysis revealed four factors to be of prognostic significance for survival: the nature of the primary tumor, the absence of local relapse, the disease-free interval and the absence of metastases in other sites. Patients with hormone-sensitive lesions or slowly-growing tumors had a better prognosis.

Adolescent↗
PubMed1987

[Pseudolinitis plastica of breast origin].

The most common type of gastric metastases secondary to carcinoma of the breast is the one showing a linitis plastica appearance. The roentgenologic aspect when performing an upper gastrointestinal examination with barium contrast is typical and allows the differential diagnosis with the primitive linitis. The linitis plastica type of metastatic breast carcinoma results from transmural infiltration of the stomach wall with initial deposit of tumor cells in the submucosal or subserosal regions. CT provide valuable information concerning the metastatic spread.

Adenocarcinoma, Scirrhous↗
PubMed1985

[Frontal and sagittal sections in whole body x-ray computed tomography].

In sufficiently supple individuals, longitudinal sections are interesting in the case of extensive lesions because they provide a global view, whereas transverse axial sections give only a segmentary view of the pathological processus. They are of value in the study of lesions of the thorax, abdomen or pelvis. However, because of their anatomical and technical restrictions, they should be reserved for certain special cases.

Humans↗
PubMed1984

Adenolipoma of the liver. A unique case with ultrasound and CT patterns.

Lipomas rarely occur in the liver. However, because of the widespread use of ultrasound and CT in the diagnosis of liver disease, one should be familiar with their appearance, as confirmed diagnosis may spare the patient major investigations. The value of CT is emphasized in association with percutaneous biopsy when the appearance of the tumour is not classical. Ultrasound patterns are discussed.

Adenoma↗
PubMed1983

Computed tomography with geometrical enlargement.

Third generation CT scanners perform examinations of small objects without employing all the detectors. Geometrical enlargement solves this problem by moving the tube-detector assembly according to the size of the object to be scanned; this improves spatial resolution, reducing both the tube current and the skin dose. Such an application for pediatric CT and small objects is of particular interest.

Child↗
PubMed1982

[Generalized adenomyomatosis of the gallbladder: ultrasonographic appearance in one case (author's transl)].

Ultrasonographic images were correlated with radiological and pathological findings in a case of generalized adenomyomatosis of the gallbladder. Emphasis is placed on the importance of the methods employed for filling the biliary tracts with opaque medium, to confirm a suspected diagnosis suggested by the heterogeneous irregular thickening, with a fringed internal limit, of the gallbladder wall.

Adult↗
PubMed1981

[Epidermoïd carcinoma of uterine cervix with bone metastases in lower limbs (author's transl)].

Bone lesions are infrequent in the evolution of epidermoïd carcinoma of the uterine cervix. Direct bone invasion from the primary tumor, extension from lymph node metastases and distant metastases can be seen. The frequency of these lesions is about 3 to 4%. Hematogen bone metastases are very uncommon. They are often located in the lower limb. We report a case of a patient with a cervical carcinoma who developed isolated bone metastases in all the bones of a lower limb.

Bone Neoplasms↗
PubMed1980

[Is bone scan useful in patients with breast cancer localized on the basis of clinical examination. 143 cases (author's transl)].

The authors present 143 cases of breast carcinoma T1 and T2, N0, N1, N2 and N3 without clinical signs of bone metastasis. They study the value of bone scintigraphy with technetium 99m labelled diphosphonates. One hundred and twelve patients had normal bone scans; 31 patiets showed abnormal fixation sites: in 23 (16%) benign bone lesions explained the increase of the bone radioactivity, in 8 cases, scintigraphy was considered to be consistent with diagnosis of bone metastasis. Metastasis has been proved in only 3 cases within a period of 2 years. The detection rate cannot be better than 5,6 per cent. Considering 50 per cent at least of these patients will eventually develop bone metastasis, the false negative rate will be about 45 per cent. Routine bone scan does not seem to be useful for patients with T1 and T2 breast cancer.

Bone Neoplasms↗
PubMed1978

[B.C.G. osteitis after immunotherapy (author's transl)].

A case of B.C.G. osteitis occuring after an attempt at the restoration of immune function in a patient with Hodgkin's disease. The diagnosis was based upon histological study of a biopsy specimen and the discovery of a B.C.G. strain. Tuberculostatic therapy resulted in local healing. The various complications and side-effects of B.C.G. immunotherapy are reported in the discussion: local reactions, regional lymphadenopathy, systemic infections, hypersensitivity phenomena, pulmonary, bone marrow and hepatic involvement.

Adult↗