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J Soga

Publications and source records attributed to J Soga.

At least 19 recordsLinked to original sources
PubMed1992

[Recurrent thymic carcinoid tumor--report of a case and review of the literature].

A case is presented of a 48-year-old male patient with thymic carcinoid tumor who was operated on twice and followed for 12 years. The original tumor was removed in 1979, and a recurrent tumor was removed 4 years later. Multiple metastases to the lungs, pleura and lymph nodes of the neck were found in 1988; chemotherapy (BAPP) and radiation therapy were not effective, and there was subsequent subcutaneous invasion of the anterior chest. We also discuss the 153 cases of thymic carcinoid tumor reported in the Japanese literature in the Niigata Carcinoid Registry.

Carcinoid Tumor↗
PubMed1990

[A carcinoma of the reconstructed gastric tube after a radical esophageal cancer operation].

Reported are five patients who developed a carcinoma of the reconstructed gastric tube. In 3 of the 5 patients, the esophageal cancer was preceded by a gastric cancer, and the intervals before the gastric cancer was detected were 34, 24, and 60 months. The gastric tube the had been reconstructed by the retrosternal rout was resected with a median sternotomy in cases 1 and 2. In case 3, since a liver and lung metastasis had been detected by routine examination, surgery was not performed. Cases 4 and 5 had an esophageal cancer associated with a simultaneous early gastric cancer located in the lesser curvature of the upper body. Thus, a esophagectomy and a partial gastrectomy were performed. Twenty-eight and 21 months later, respectively, an early gastric cancer was found at the stump of the gastric tube that had been reconstructed by the retrosternal route. Endoscopic laser therapy was subsequently employed for both patients. Because of these findings, the author have concluded that postoperative serial examination of the gastric tube are very important, since cases of a gastric tube cancer are increasing.

Aged↗
PubMed1989

[Carcinoids].

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Antineoplastic Combined Chemotherapy Protocols↗
PubMed1988

[Clinicopathological study of early gastric cancer--indication of conservative surgery and radical endoscopic treatment of early gastric cancer].

Clinicopathological factors such as depth of cancer invasion, size, gross type, frequency of metastases to regional lymph nodes, and distant prognosis were evaluated in last consecutive 339 cases with solitary early gastric cancer. The conservative surgery, that is, subtotal gastrectomy with complete dissection of lymph nodes of group 1 and selective celiac group and partial bursectomy, would be indicated for early gastric cancers located in antrum or corpus. But if the metastasis to the group 2 lymph nodes is suspected during the surgery, it is necessary to dissect lymph nodes en bloc more than group 2. The results, concerning the type of early gastric cancer without lymph node metastasis and the indication of endoscopic treatment, were as follows; 1. Intramucosal cancer of elevated type less than 2 cm in diameter. 2. Intramucosal cancer of depressed type less than 1cm in diameter, without peptic ulcer within the lesion, and a differentiated tubular adenocarcinoma histologically. 3. Intramucosal cancer of flat type less than 2 cm in diameter. But it is difficult to detect the depth of cancer invasion and lymph node metastasis preoperatively. We would emphasize that endoscopic treatment should be indicated in the case for which surgical treatment is not indicated.

Adult↗
PubMed1986

[Diagnosis and treatment of carcinoids of the large intestine].

A total of 1,279 cases of carcinoids reported in Japan included 882 cases (69.0%) in the digestive organs. Among the latter cases, carcinoids of the large intestine consisted of (A) 320 cases (36.3%) in the rectum and (B) 46 cases (5.2%) in the ileocecal region, cecum and colon excluding the rectum. The predominant difference of signs and symptoms between (A) and (B) was a high incidence of large palpable abdominal tumors and obstructive findings (ileus) in the latter and a high incidence of small-sized tumors and anorectal disturbances such as hemorrhoids, anal bleeding or anal pain in the former. The incidence of the carcinoid syndrome in (B) was 13.0%, considerably higher than the average of the Japanese series (4.1%) and the America-Europe series. Silver impregnation methods with a combination of Grimeluis' argyrophil and Masson-Fontana's argentaffin reactions were considered to be useful methods for diagnosis of carcinoids of the large intestine. The rate of metastasis in relation to tumor size in the Japanese series was 6.1% for lesions less than 1.0 cm in size and 25.7% for lesions between 1.0 and 2.0 cm. Because of a high incidence of metastasis in (B), 41.3%, greater than that for ordinary carcinoma in the identical sites, it was emphasized that surgical treatment of carcinoids of the large intestine should be principally in accordance with that for ordinary carcinomas.

Antineoplastic Combined Chemotherapy Protocols↗
PubMed1985

Granular cell tumors of the esophagus: a report of two cases and review of the literature.

Two patients with granular cell tumors of the esophagus are presented. Both were men, 54 and 51 years old, respectively, and without tumor-related complaints. Diagnosis was made by esophagogram and endoscopic biopsy. The two patients were treated with a left thoracotomy and local excision of the tumors. A review of the world literature was carried out and data of general interest were collected. The symptoms and management of esophageal granular cell tumors, as well as histogenesis, are discussed.

Adult↗
PubMed1979

Difference in calcium metabolism following Billroth-I and Billroth-II procedures for gastric and duodenal ulcers.

There have been 7 patients with postoperative osteomalacia in our series of 500 patients who had a gastrectomy for gastric or duodenal ulcers. All seven of these patients had a Billroth-II type gastrojejunostomy or esophagojejunostomy which caused food to bypass the duodenum and the upper part of the jejunum, and six of these patients showed milk intolerance and had diarrhea on food other than cow's milk. From this finding, it may be surmised that patients are predisposed to osteopenia after gastrectomy due to disorder in the process of calcium absorption and they develop osteomalacia when treated with the Billroth-II procedure, showing milk intolerance and diarrhea on food other than cow's milk.

Adult↗
PubMed1976

Clinical and pathophysiological evaluation of esophageal and reconstruction using gastric tube and pedicled colon segment.

Pathophysiological and nutritional conditions were compared after esophageal reconstruction in 15 patients with a gastric tube and in 12 patients with a pedicled colon segment for the treatment of esophageal cancer. There was no significant difference in the postoperative nutritional index, iron and vitamin B12 metabolisms. On the other hand, the long gastric tube from the greater curvature of the stomach used as an esophageal substitute retained some secretory functions of both exocrine and endocrine although the effect of truncal vagotomy may have to be taken into consideration.

Aged↗
PubMed1975

Role of preoperative administration of bleomycin and radiation in the treatment of esophageal cancer.

The preoperative use of Bleomycin (BLM) alone or combined with irradiation in the treatment of esophageal cancer was evaluated in 58 patients who underwent surgical removal of the lesion for the past three and a half years. Histologic study showed such preoperative treatment is effective in inducing favorable changes in neoplastic cells in 69 per cent (40/58) of the primary lesions and in a significant number of involved lymph nodes of the second or the third groups. The study clearly suggests that preoperative Bleomycin administration combined with irradiation may be an useful adjunct preoperative procedure in esophageal cancer.

Adult↗
PubMed1975

Argyrophil cell microneoplasia in the Mastomys' stomach--an observation on early carcinoid formation.

To analyze the early stages of argyrophil cell carcinoid growth, complete serial sections were cut from the glandular portion of the stomachs of 22 Mastomys and submitted to Sevier-Munger's reaction. The 154 grossly invisible foci of argyrophil cell microproliferation thus detected were classified into three stages of microproliferations (I, II, and III), and the last stage was definitely a microcarcinoid. There was a gradual transition in cell proliferation among these three stages; the first stage (microproliferation I), in which the cells were morphologically indistinguishable from those of hyperplastic proliferation by general morphologic criteria, was where the initial change of argyrophil cell carcinoid formation was detectable by a light microscope. Whereas multiple occurrences of microcarcinoids accounted for the multiplicity of well-developed tumors in the stomachs of Mastomys, a well-developed carcinoid in this species was formed by the confluence of several microcarcinoids.

Animals↗