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Biomedical subjects

J Simon

Publications and source records attributed to J Simon.

At least 541 records · Page 30Linked to original sources
PubMed1982

Love: addiction or road to self-realization, a second look.

One aspect of self-realization is to work on constructive intimate relationships in which another person adds to the richness of our existence and expands our horizons. The other person is not a substitute for our self-development nor someone who can make up for our developmental deficits. (Or if this is the case, at least one should become aware of it, since such a relationship is most likely not completely free of some contamination from the past.) When we are in touch with our active, striving, self-realizing self, we have the freedom and choice to "love." Loving implies that we can accept the person for what and who he is, apart from our compulsive needs from him. Certain needs are real and if not met, the relationship is not gratifying. Sharing warmth, caring, affection, and mutual growth as individuals as well as a couple are aspects of a constructive relationship. Hopefully, we will also expand our horizons to include friendships (outside marriage), relationships between equals, whether of the same sex or not, which include intimacy, loyalty, sharing that is unconditional and unselfish. Though it has been said that friendship, in the true sense of the word, is the most singularly uncultivated capacity in American social relations, when we do achieve it, it can add tremendously to our existence.

Adult↗
PubMed1982

Longitudinal study of adiposity in chickens selected for high or low abdominal fat content: further evidence of a glucose-insulin imbalance in the fat line.

Selected fat (FL) or lean (LL) lines of chickens have been further studied. Total lipid and abdominal fat content and size of adipocytes isolated from the gizzard were significantly increased in both sexes of the fat line from 2 to 4 weeks of age onwards. The divergence in abdominal fat content was maximum at 9 weeks of age. Both in the fed and the fasted state, the plasma glucose level was lower in FL than in LL chickens, at hatching and shortly after. This was not, however, associated with higher plasma insulin levels in FL chickens. At 2 weeks of age, insulin content of the pancreas did not differ. From 5-8 weeks of age after ad libitum refeeding or forced-feeding following a fast, plasma glucose increased to similar levels in both lines but in contrast, plasma insulin levels were largely enhanced in FL chickens. At 17 weeks of age, glucose clearance was faster in FL chickens and associated with a slightly (although nonsignificant) higher insulin release. In eggs laid by FL hens, yolk weight was disproportionately increased and albumen glucose content was decreased. During the last third of embryonic development, plasma glucose levels were similar in both lines at the F4 generation and in contrast lower in the FL embryos at the F5 generation. The physiological situation of FL chickens appears therefore very similar to short-lived preobese state observed in mammals.

Abdomen↗
PubMed1982

[Inefficacy of post-hatching overfeeding in modifying the subsequent feeding behavior, growth and body composition of the chicken].

The effects of post-hatching overfeeding were studied in the chicken. Hubbard and Leghorn chickens were force-fed daily from 0 to 9 days of age by a factor of 1.5 times the food intake of the ad libitum-fed group, then 1.2 times that intake from 10 to 15 days. Thereafter, they were refed ad libitum. As might be expected, body weights were increased at the end of the forced-feeding period in overfed chickens of both breeds. Liver weight and malic enzyme activity and the size of adipocytes isolated from subcutaneous and gizzard adipose tissues (only measured in the Leghorn breed) were also increased by overfeeding. After ad libitum refeeding, weekly food intake and body weight gain up to 56 days of age were normal in overfed Hubbard chickens as compared to the controls. In overfed Leghorn chickens, those parameters decreased temporarily (1-2 weeks) and then became normal. At 28 and 35 days of age, the hourly distribution of daily food intake was not modified by prior overfeeding. Fasting plasma glucose levels were significantly lower at 15 and 42 days of age but normal at 56 days in overfed chickens. Glucose tolerance at 15, 42 and 56 days and abdominal fat content at 56 days were not modified by overfeeding. The glucose tolerance of Leghorn chicks was similar to that of Hubbard chickens at 14 days, but faster at 42 and 56 days. Therefore, overfeeding chickens immediately after hatching does not affect subsequent appetite, body weight gain or body fat content. This is contrary to the results observed in the rat and the mouse.

Adipose Tissue↗
PubMed1982

A/B behaviour pattern not correlated with other coronary risk factors in industrial plant populations.

The behaviour pattern was assessed in two groups of middle aged men, 157 subjects selected randomly from a coronary risk group of 1553 subjects and 83 respondents for physical fitness testing. The number of risk factors i.e. smoking, hypertension, hypercholesterolemia, angina pectoris by chest-pain questionnaire and positive family history was higher in the physical fitness testing respondents than in randomly selected subjects, the difference being highest for A Type men. No correlation between the behaviour pattern and prevalence of RF was found. Subjects with higher score of neuroticism in EPI were the heaviest smokers.

Adult↗
PubMed1981

Vaccinia infection of the nervous system in animals with normal and altered immune reaction.

The outcome of viral infection appears to be the result of a complex interplay of both viral and host factors. The virus-host cell relationship as well as the host's immune response are the major factors determining the type of infection and the expression of the disease. Demyelination disease appears to be rare complication of a systemic viral infection. The mayor factor in its expression is an altered response to the virus favoring the establishment of a noncytocidal abortive infection of the glial cells, which in turn induce a complex of potentially pathogenic immune mechanisms.

Animals↗
PubMed1981

Evidence of a glucose-insulin imbalance and effect of dietary protein and energy level in chickens selected for high abdominal fat content.

Effects of dietary protein or energy level on growth and physiological parameters were investigated in growing chickens selected for high (fat line, FL) or low (lean line, LL) abdominal fat but similar body weight. The FL birds deposited consistently more abdominal fat (about two-fold) and had poorer feed conversion, irrespective of diet. Increasing the ratio of energy to protein increased fat deposition similarly but at different levels. Body weight and feed consumption showed only minor and inconsistent differences and feed consumption following a fast and body temperature in the fed or the fasted-state showed no differences between lines. Fasting plasma glucose levels were similar for both lines at hatching but consistently lower in FL birds thereafter. This was matched by higher fasting plasma insulin levels. A similar relationship was also observed in fed FL birds at 2 weeks of age. Glucose disposal rate was faster in FL birds at 4 and 6 weeks but normal by 8 weeks. The glucose-induced insulin release was higher in FL birds at 6 and 8 weeks, indicating a normal sensitivity to insulin at a young age, with the development of a tissue insulin resistance by 8 weeks of age. The primary mechanism responsible for the fattening of FL birds appears therefore to be greater insulin release from the pancreas of the FL birds soon after hatching.

Abdomen↗
PubMed1981

Interactions between St. Lucian Biomphalaria glabrata and Helisoma duryi, a possible competitor snail, in a semi-natural habitat.

In artificial drains similar to those used in banana culture on St. Lucia, Helisoma duryi, the rams-horn snail, controlled Biomphalaria glabrata, intermediate host of schistosomiasis on that island. Time required for elimination of B. glabrata depended on environmental temperature and numbers of H. duryi initially introduced in the drains. Best fit to the data was given by the equation for the logistic curve rather than by an equation for unlimited growth. Multiple regression analyses of natality and mortality rates of both species of snails indicated that populations of B. glabrata were regulated by temperature rather than by density-dependent means while numbers of H. duryi were strongly influenced by numbers of rams-horn snails already present in the drains. Fitting of snail shell growth to von Bertalanffy equations showed that H. duryi shell diameter was uninfluenced by environmental temperatures or presence of B. glabrata while growth of the intermediate host was strongly affected both by temperature and numbers of H. duryi.

Animals↗