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Biomedical subjects

J Scott

Publications and source records attributed to J Scott.

At least 685 records · Page 38Linked to original sources
PubMed1975

Folic acid deficiency in the United States: folate assays in a prenatal clinic.

Tissue deficiency of folic acid, as measured by a red cell folate level below 150 ng. per milliliter, was present in 16 per cent of 110 sequential pregnant women at the time of their first prenatal visit to a municipal clinic. A further 14 per cent of subjects had red cell folate levels in the range "suggestive but not conclusive for tissue folate depletion" (150 to 199 ng. per milliliter). All of the subjects were from low-income families in New York City and most were black or of Puerto Rican origin. Serum folate levels showed good general correlation with red cell folate but were of less value as a diagnostic test, since they were below the lower limit of normal in 64 per cent of subjects, including many subjects who did not yet have low tissue folate. In contrast to their value in other folate deficiency states, neutrophil lobe counts showed no correlation with serum or red cell folate levels in pregnancy and thus appeared of little diagnostic value in pregnancy. It is suggested that surveys of folate deficiency in other pregnant population groups in the United States be carried out. These results support the recommendations of the Committee on Maternal Nutrition and the Committee on Dietary Allowances of the Food and Nutrition Board, National Research Council (U.S.A.) that folic acid supplements (200 to 400 mug per day) should be taken throughout pregnancy.

Black or African American↗
PubMed1975

Ethnic and age differences in mental health measurements.

Data gathered in a survey of 1441 respondents were analyzed to study the influence of chronologmost equal representation of six age groups (20-29, 30-39, 40-54, 55-64, 65-74, 75-94), and three ethnic groups (Blacks, Anglos, Mexican-Americans). The sample includes equal representation of both sexes and two socioeconomic levels. The Twenty-two Item Screening Scale and the Affect Balance Scale are used as measures of mental health. The analyses show age-related and ethnic-related patterns; each pattern, however, is independent of the other. The age-related pattern is the same within the three ethnic groups, and the ethnic pattern is independent of age. Anglos report significantly more psychiatric symptoms, especially those of one factor grouping named "anxiety," and they report more recent experiences with both positive and negative affect than do Mexican-Americans and Blacks. The elderly persons "well enough" to participate in a long interview express no significant increase in symptomatology compared with younger groups. If the symptom expression is broken into several categories based on factor analysis, we find a small, significant increase in symptom expression by older groups on the factor grouping named "depression." Additionally, the older groups compared with middle-aged and younger groups, report less positive and negative affect expression.

Adult↗
PubMed1974

Treatment of rheumatoid arthritis with fenoprofen: comparison with aspirin.

Fenoprofen, a compound with analgesic, anti-inflammatory, and antipyretic properties in animals, has been compared with placebo in a double-blind cross-over trial in 60 patients with rheumatoid arthritis. There was a statistically highly significant reduction in pain, duration of morning stiffness, analgesic requirements, and articular index, with increase in grip strength. There was no significant reduction in joint size or temperature. In a subsequent double-blind group-comparative study fenoprofen proved to be as effective as aspirin in relieving the symptoms of rheumatoid arthritis, with strikingly fewer side effects. Almost half of the patients taking aspirin were unable to tolerate the drug in adequate dosage for six months. The remainder were able to take on average only 4 g daily, and at this dose almost half still complained of tinnitus and deafness.Fenoprofen is likely to be useful for patients who cannot tolerate aspirin and other more toxic anti-inflammatory drugs or whose disease is not of sufficient severity to justify their use.

Acetaminophen↗