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Biomedical subjects

J Schmidt

Publications and source records attributed to J Schmidt.

1,102 records · Page 62Linked to original sources

Identity of non-malignant human urothelial cell lines classified as transformation grade I (TGrI) and II (TGrII).

Restriction fragment length polymorphism (RFLP) and marker chromosome or isozyme analysis were used to study the identity of 7 human urothelial cell lines selected according to their HLA-A,B phenotype. The results confirmed that the cell lines Hu961b, Hu1125, Hu1694, Hu1752, Hu609 and HCV-29 were genuine cell lines of different origin, while Hu1734 and HCV-29 were of the same origin. Hu609 was recorded to be derived from a female. However, the presence of a Y chromosome indicated either false labelling or cross-contamination. Analysis of a series of frozen stocks of Hu609 cultures showed that "malignant transformation" of these cultures was due to cross-contamination.

Cell Line↗

[Evaluation of change by patients and staff and specialist physicians in psychosomatic rehabilitation--a catamnestic comparison].

Considering three single outcome criteria reflecting the change of a) physical state, b) general condition and c) ability to work catamnestic ratings of patients and of external doctors are compared. The ratings were assessed by questionnaires 12 months after the end of inpatient psychosomatic treatments ("direct measurement of change"). Mayor findings are: a) the judgements of both data sources indicated positive change or improvement for a majority of patients, b) the ratings of the external doctors were more favourable than the patients' self-ratings, c) moderate but statistically significant correlations between the ratings of the two groups of judges were to be observed. From a more methodological point of view it will be attempted to analyze the meaning of these correlations somewhat more in detail.

Adult↗