Biomedical subjects
Publications and source records attributed to J S Phillips.
This case report presents profound unremitting hearing loss in a 76-year-old man after having a bilateral knee replacement. There have been no other cases of permanent post-operative deafness after joint replacement in the world literature. Sudden post-operative deafness is rare. We conclude that this man's deafness is due to a fat embolism in his auditory circulation.
S. W. Gilliland (1993) has proposed a model of perceived selection system fairness to help understand applicants' prehire and posthire behavior. The present study aimed to verify and extend his framework by investigating the role of job context in the formation of fairness perceptions of biodata. A sample of 255 students (108 men, 147 women) completed an operational biodata instrument, believing that it would be used to hire persons for either international, local, or unspecified entry-level managerial positions. Participants were then presented with outcome information (selected or rejected for further consideration). Consistent support was found for the research hypotheses derived from the Gilliland model. Participants' perceptions of the fairness and job relatedness of biodata were affected by the selection context and decision outcome. The importance of considering selection context in assessments of perceived test fairness is discussed.
Although the beneficial effects of high-quality leader-member exchange (LMX) relationships have been well-documented in the leadership literature, much less is known about the potentially damaging effects of poor exchange relationships. Using 150 intact leader-member dyads, the authors investigated the relationship between LMX and supervisors' reports of employee retaliation behavior, performance, and citizenship. Results indicated that performance and citizenship were positively related to LMX. More important, LMX was negatively correlated with retaliation behavior. Supervisors reported that subordinates in poor exchange relationships were more likely to engage in retaliation against the organization than subordinates in high-quality relationships. The lack of a high-quality exchange relationship was, therefore, not just associated with the absence of positive consequences but also led to reports of potentially disruptive behaviors.
The immortalization of human diploid fibroblasts requires the circumvention of both the senescence (M1) and crisis (M2) mechanisms of growth control. Cells expressing the SV40 T antigen virtually always bypass senescence, but only rarely escape crisis. The low frequency of this latter event indicates that cellular mutations are necessary to escape crisis. Thirteen subpopulations of T antigen-expressing human fibroblasts were cultured into crisis. Colonies that appeared to resume growth were assayed for telomerase activity, telomere maintenance, and the immortal phenotype. Our results show that 33 of 35 colonies were telomerase negative and were not immortal. Two colonies were telomerase positive when assayed in the first approximately 15 population doublings after crisis. The first was strongly positive, maintained telomeres at a stable short length, and was later determined to be immortal. The second initially had a weak telomerase signal, grew extremely slowly, and when examined had greatly elongated telomeres consistent with the ALT (alternative lengthening of telomeres) mechanism of telomere maintenance. These cells eventually grew faster and were later determined to be immortal. Additionally, two subpopulations had initially weak and later strong telomerase activity and the cells never entered a defined crisis period. We observed a perfect correlation between telomere maintenance and escape from crisis, supporting the hypothesis that the lack of stable telomeres causes crisis and that the ability to maintain telomeres abrogates crisis.
The role of attributions in judgments of sex discrimination was examined in 2 laboratory experiments. In Study 1, participants read 1 of 12 brief scenarios in which limited information about the strength of evidence against a fictitious corporation and occupational gender stereotype were manipulated. Results suggested that attributions mediated the relationships between participants' gender, strength of evidence, and discrimination judgments. In Study 2, participants were provided with 1 of 3 detailed, typewritten summaries of evidence presented in a sex discrimination trial. Results indicated that jurors' gender was again significantly related to attributions and to sex discrimination judgments even in the face of substantial objective information related to the case. The variance in observers' judgments associated with gender, however, appeared to be greatest when information about the organization's guilt or innocence was equivocal.
The Department of Defense has embraced utilization management (UM) as an important tool to control and possibly decrease medical costs. Budgetary withholds have been taken by the Office of the Assistant Secretary of Defense (Health Affairs) to encourage the military services to implement UM programs. In response, Walter Reed Army Medical Center implemented a UM program along with other initiatives to effect changes in the delivery of inpatient care. This paper describes this UM program and other organizational initiatives, such as the introduction of new levels of care in an attempt to effect reductions in length of stay and unnecessary admissions. We demonstrate the use of a diversity of databases and analytical methods to quantify improved utilization and management of resources. The initiatives described significantly reduced hospital length of stay and inappropriate inpatient days. Without solid command and clinical leadership support and empowerment of the professional staffs, these significant changes and improvements could not have occurred.
The effects of different temperatures and relative humidities (RHs) were tested on various reproductive parameters of Ornithodoros turicata, an argasid tick that inhabits gopher tortoise burrows in Florida, USA. The pre-oviposition, oviposition and incubation periods of the ticks decreased as temperature increased. These periods were also affected by the RH. The number of eggs oviposited was affected significantly by the combined effect of temperature and RH. Fewer eggs were laid by ticks in the 24 degrees C regimes and the 27 degrees C/95% RH regime compared to those in the other temperature/RH groups. There was an inverse relationship between the number of eggs oviposited and the percentage of hatched larvae that was correlated with the temperature and RH. Ticks reared at 27 degrees C/90% RH and 30 degrees C/90% RH laid more eggs than those reared in the other combinations of temperature and humidity but fewer larvae hatched from these eggs. The reproductive fitness index (RFI) values were highest in females held in the 24 degrees C groups and the 30 degrees C/95% RH group, although significantly more larvae hatched at the lower temperatures. The optimum reproductive conditions for O. turicata under laboratory conditions appear to be 24 degrees C and 90-95% RH. While mating occurred at all temperatures, none of the females laid eggs at 22 degrees C. The ticks may move preferentially to low temperatures when not feeding to remain above the critical equilibrium humidity and/or below the critical metabolic level necessary for prolonged survival. However, most female ticks oviposited after 45 days when moved to 27 degrees C/95% RH. Ornithodoros turicata females may have a limited capability to delay oviposition until an optimal microenvironment for egg deposition can be located in the burrow.
The effects of photoperiod on the feeding, development and quiescent behavior of the burrow-dwelling soft tick, Ornithodoros turicata (Dugès) were investigated. Ticks were assigned randomly to either continuous darkness (DD), a short-day photoperiod (L:D 10:14), a long-day photoperiod (L:D 14:10) or constant light (LL). Ticks reared under constant light succumbed to much higher mortality than those reared under the other conditions. However, photoperiod did not induce quiescent behavior in O. turicata; the ticks were active and fed regularly throughout the study. Also, ticks reared in continuous darkness developed more slowly than those reared under short-day or long-day conditions. In contrast, pre-oviposition period was significantly longer for ticks reared in long-day conditions. Egg-hatch success was significantly higher for ticks reared in continuous darkness than for those reared under the photoperiods. The stage-specific effects of photoperiod on O. turicata are adaptive; these ticks very likely utilize photoperiod information to predict seasonal conditions.
The rate of oxygen consumption was investigated in fed larval, nymphal and adult Ornithodoros turicata ticks and in starved nymphal and adult ticks. Oxygen consumption rate of fed adult ticks increased with increasing temperature. The metabolic rate of adult ticks was affected by starvation whereby starved adult ticks showed a significantly lower oxygen consumption than their fed counterparts. The oxygen consumption rate of fed female ticks was significantly higher than that of fed males but, there was no significant difference between the oxygen consumption rates of starved female versus starved male ticks. Oxygen consumption of fed larvae was significantly greater than those of fed first through third instar nymphs. Fed and starved nymphal ticks as well as fed adult ticks ventilated continuously. In contrast, starved adults ventilated discontinuously. The ability to reduce metabolic rate, plus the capability to ventilate discontinuously allow O. turicata adults to cope with prolonged starvation.
This study compared behavioral and emotional problems reported by parents and teachers in Chinese urban and rural samples and demographically similar American samples. Parents of 469 6-to-13-year-old children of each nationality completed the Child Behavior Checklist (CBCL). Teachers completed the Teacher's Report Form (TRF). Cross-cultural differences were generally modest in magnitude. Chinese children scored higher on TRF Delinquent Behavior and Anxious/Depressed syndromes, and on Internalizing. American children scored higher on CBCL Aggressive Behavior and TRF Attention Problems syndromes. Boys exhibited more externalizing behaviors across both cultures. The mean correlation between parent and teacher ratings was .36 in the Chinese sample and .29 in the American sample, a nonsignificant difference. Findings indicate considerable similarity between problems reported for children in very different societies.
Amblyomma americanum and A. maculatum were studied to determine if genital sex pheromones were present, as reported in Dermacentor species. Chemical analysis of methanol extracts of the anterior reproductive tracts (source of the genital sex pheromone) of A. americanum and A. maculatum confirmed the presence of the same fatty acids that act as components of the genital sex pheromone in Dermacentor variabilis and D. andersoni. In both Amblyomma species, removal of the anterior reproductive-tract of fed females eliminated the male copulatory response. For A. americanum, use of anterior reproductive tract extracts made with water, methanol, ether and hexane elicited significant probing and copulatory responses by conspecific males. However, in A. maculatum, use of anterior reproductive-tract extracts made with water, methanol, ether, chloroform:methanol (4:1), hexane and pentane did not restore mating response by males. Treatment with known components of Dermacentor genital sex pheromones elicited weak but significant responses in A. americanum, but did not restore male mating responses in A. maculatum. These results indicate that genital sex pheromones exist in A. americanum and are not restricted to the genus Dermacentor. Characteristics of the Amblyomma genital sex pheromone, however, do differ considerably from those in Dermacentor. No genital sex pheromone was present in A. maculatum.
Previous surveys have revealed troubling gaps between training and research and practice in psychotherapy. In this study, a selective review of research on child therapy and therapy training was conducted in order to address questions concerning who, what, how, and when to train child therapists. This review revealed substantial gaps in our current empirical knowledge about child therapy training, but some promising leads as well. A science-based approach to child therapy training is advocated.
Despite the general agreement that stress plays a role in everyday life, there continues to be substantial controversy about how stress can be managed at the worksite. During the last decade, our knowledge of stress management interventions has increased substantially. Despite this improvement, deficiencies in the literature exist. In this article, we offer a framework that may be used for viewing organizational stress interventions, briefly review some of the stress management intervention literature in the context of this framework, and identify future needs that may be particularly appropriate for organizational psychologists to address.
Strube's (1987) self-appraisal model of Type A behavior suggests that externally mediated performance goals that are useful for assessing task-related competencies will possess greater utility and be more satisfying to Type A persons than to Type B persons. In contrast, because Type Bs may have an aversion to competency verifications, they should be more satisfied than Type As when goals are uninformative about task-related competencies. The 102 undergraduate Ss performed either a word puzzle or proofreading task under 1 of 4 goal conditions that varied in terms of the goal's instrumentality for assessing competencies and for obtaining a financial incentive. Results are generally consistent with this prediction, thereby providing verification for one of the more basic propositions derived from the self-appraisal model.
The chemical basis for the ability of fed males of Dermacentor variabilis (Say) and D. andersoni (Stiles) to differentiate conspecific and heterospecific females was investigated using a neutered female bioassay. Male D. variabilis responded strongly in a dose-response manner to increasing concentrations of stearic and palmitic acids and an extract of the anterior reproductive tract (ART) of fed D. variabilis females. Mating responses were greatest at 1 microgram of fatty acid and 1 female equivalent (FE) of ART extract. D. variabilis males also responded strongly to D. variabilis females treated with a conspecific ART extract and a mixture of fatty acids simulating the extract; responses were moderate to D. andersoni females treated with the same extract or fatty acid mixture. They also responded moderately to conspecific females treated with D. andersoni extract. Male D. andersoni displayed moderate increases in mating behavior over a range of concentrations of stearic and palmitic acids and conspecific ART extract. D. andersoni males mated only with D. andersoni females treated with a conspecific extract or a mixture of fatty acids simulating the extract. Mating by D. andersoni did not occur in response to D. variabilis females treated with D. andersoni or D. variabilis ART extracts. Stearic acid alone or in combination with 20-hydroxyecdysone, oleic, or myristic acid did not account for the specificity of response of either species. D. andersoni males were much less responsive to fatty acids, alone or in mixtures, than D. variabilis males. These findings indicate that fatty acids are important in mate recognition by D. variabilis, but explain only part of that by D. andersoni. The possibility is raised that another compound is required for mate recognition by D. andersoni.
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