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Biomedical subjects

J S Murty

Publications and source records attributed to J S Murty.

At least 37 records · Page 2Linked to original sources

Palmar main line polymorphisms in cataracts.

The palm prints of patients with different types of cataract (total, nuclear, zonular, cortical and complicated) were analysed for main line terminations and compared with those of a random population. The cases were also grouped into congenital, juvenile and senile types for broader comparison. The results showed significant variations for all the 4 main line terminations (D, C, B and A) in senile and cortical cataracts, while among other types of cataract, congenital cases differed significantly in D and A line, zonular in C and A line and nuclear in B and A line terminations compared with controls. A comparison of familial and isolated cases revealed significant differences for D and A line terminations only in cases of senile cataract. The main line terminations also indicated considerable sex-dependent heterogeneity among the diseased and control subjects. The significance of the results obtained are discussed in terms of pleiotropic mechanisms leading to the formation of cataract.

Adolescent↗

Genetic studies on the Chenchu Tribe of Andhra Pradesh, India.

A total of almost 200 members of a tribal group, the Chenchu from the Mahabubnagar and Kurnool districts of Andhra Pradesh, have been tested for electrophoretic variation in a number of red cell enzyme systems. The former population has also been tested for ABO, MN and Rh blood group systems and for the serum proteins Hp, Tf and albumin. The most significant findings were the presence of the gene ry, and the occurrence of a polymorphism in PHI with the variant gene PHI5 having a gene frequency of 4%.

Blood Group Antigens↗

Dermal ridge configurations in retinal detachment.

An analysis of dermal ridge configuration in 95 retinal detachment patients showed characteristic association with different aetiological bases of the condition like myopia, aphakia, vitreous degeneration and idiopathic factors. The study revealed a significantly high frequency of whorls on fingers and low mean interdigital ridge counts in the patients as compared to controls. Aphakic detachments showed maximum and vitreous degeneration detachments minimum variation from controls for all characters except the main line terminations. Of all the parameters studied, main line terminations contributed maximum for the variation between the detachment types. The results are discussed in light of the contribution of dermatoglyphic characters to the aetiology of retinal detachment.

Adult↗

Genetic studies on the Kolams of Andhra Pradesh, India.

A total of 220 persons belonging to the Kolam tribe in the Adilabad District of northwest Andhra Pradesh have been tested for 18 red cell eyzyme systems and for haemoglobin. Generally, the gene frequencies for the systems which showed electrophoretic variation were within the range for Indian populations; the gene frequency for AK1 is high by Indian standards and Hb AS is present. LDH Calcutta 1 was not detected in this population and a single example of PHI 2-1 was observed.

Acid Phosphatase↗

Variation and inheritance of relative length of index finger in man.

The length of index finger relative to fourth finger has been measured on parents and children in 190 families belonging to an endogamous Reddy community of Nalgonda District, India. The distribution of relative index finger length among various family groups was unimodal and symmetric. Heritability estimates based on parent-offspring regressions indicate a moderate level (40--70 percent) of additive genetic variance. There was no evidence for the influence of sex-linked additive genes.

Adolescent↗

Hydrogen cyanide smell sensitivity in some Indian populations.

The ability to smell HCN has been examined in a sample of 2619 subjects from Hyderabad, Andhra Pradesh, belonging to different Indian ethnic groups. One single antimode, between concentrations of 5% and 10%, has been found. No sex nor ethnic differences were noted. Previous claims of possible sex-linked inheritance could not be confirmed.

Adolescent↗

Factors influencing hypohaptoglobinaemia in newborn in India.

An attempt is made to enumerate the effects of some factors on hypohaptoglobinaemia in a sample of 389 infants (along with their mothers) who were classified electrophoretically for haptoglobins (Hp). 85 . 5% of infants were Hp 0-0. There was no direct effect of birth-weight on the frequency of Hp 0-0 but there was a significant interaction between maternal haptoglobin type and birth-weight of newborn, showing an excess of 2-2 among mothers of low birth-weight babies, who were mostly Hp 0-0. Some trend towards reduced Hp 0-0 frequency among premature babies was discernible. There was a significant effect of parity on the frequency of detectable haptoglobin patterns among low birth-weight infants. An increase in the frequency of haptoglobin pattern was observed with increase in parity and birth-weight. The distributions of detectable haptoglobin patterns among newborn and mothers were similar. ABO incompatibility, sex, economic status and caste variation did not show any effects on the frequency of Hp 0-0.

Birth Weight↗