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Biomedical subjects

J S Lewis

Publications and source records attributed to J S Lewis.

At least 73 records · Page 4Linked to original sources
PubMed1992

Corneal argyrosis associated with silver soldering.

We report a patient who developed corneal argyrosis secondary to occupational silver soldering. Clinically, the cornea was notable for a green-brown discoloration localized to Descemet's membrane by slit-lamp biomicroscopy. Silver particles were identified within the anterior three eighths of Descemet's membrane by light and electron microscopy and energy-dispersive x-ray microanalysis. To our knowledge, the association between corneal argyrosis and silver soldering has not been previously reported.

Aged↗
PubMed1991

Functional use of the Nucleus 22-channel cochlear implant in the elderly.

A questionnaire was sent to 101 Nucleus 22-channel cochlear implant recipients aged 65 years and older to investigate the perceived impact of cochlear implantation on their quality of life. The questionnaire was designed to gain insight into the patient's daily use of the Nucleus implant. Sixty-seven questionnaires were returned over a 3-month period. The results of the survey showed that elderly cochlear implant patients obtained similar benefits to younger adult patients who were implanted with the same device. We believe that the results of this study will aid other centers when counseling elderly patients on the expected daily functional benefits of this device.

Aged↗
PubMed1991

Ab externo sulcus fixation.

A new suturing method for sulcus fixation of posterior chamber lenses is described. This technique involves using a 28-gauge hollow-bore needle on an insulin syringe and a straight suture needle carrying 10-0 polypropylene. Both of these needles penetrate the eye wall in ab externo fashion, with measurements guiding their insertion. This technique promotes reproducible suture placement and reliable sulcus fixation of the implant.

Cataract Extraction↗
PubMed1990

DNA probe confirmatory test for Neisseria gonorrhoeae.

A DNA probe test for the culture confirmation of Neisseria gonorrhoeae in clinical isolates was evaluated with 156 isolates of N. gonorrhoeae and 120 isolates of nongonococcal Neisseria species, organisms representative of other genera within the family Neisseriaceae, and organisms isolated on media selective for N. gonorrhoeae. The 30-min test used a chemiluminescent DNA probe that was homologous to rRNA sequences of N. gonorrhoeae. We report here a specificity and a sensitivity of 100% with the 276 clinical isolates tested, including 43 gonococcal strains that had been misidentified by other methods.

Bacteriological Techniques↗
PubMed1983

Surgical management of tumors of the middle ear and mastoid.

The author has presented the two most common tumors of the ear, cancer of the ear and glomus tumors. Most experience has been with extensive carcinomas involving the temporal bone and indeed the author has treated 132 cases with cancer of the ear, of which 105 cases were resectable. The total experience yielded a cure rate of 28 per cent. The best management program should entail an en bloc resection of the temporal bone followed by post-operative radiation therapy. Glomus tumors are generally benign and when confined to the middle ear present no surgical problem. However, when extension occurs into the jugular bulb region and into the jugular vein, the surgery becomes more formidable and the extent of the tumor should be established before surgery. Wide surgical exposure should avoid entering into the tumor prematurely and thereby compromising a total resection. Advanced extension of the tumor intracranially mandates a combined neurosurgical and otolaryngological approach. Radiotherapy, while not destroying the glomus tumor, will shrink down the size of the tumor by causing thrombosis in its blood vessels and subsequent fibrosis of the tumor itself. The management of each tumor should be individualized according to its size, location, and the general status and age of the patient.

Adenocarcinoma↗
PubMed1983

Ammonium bicarbonate as a replacement for carbon dioxide in Transgrow bottles for primary isolation of Neisseria gonorrhoeae.

Transgrow bottles with medium containing ammonium bicarbonate and Transgrow bottles gassed with 10% carbon dioxide performed equally well in detecting Neisseria gonorrhoeae in 434 clinical specimens. It appears that incorporation of ammonium bicarbonate into the medium increased the efficiency of the manufacturing process while maintaining the effectiveness of the medium.

Bacteriological Techniques↗
PubMed1982

Culture medium for confirmation of penicillin-resistant and penicillinase-producing Neisseria gonorrhoeae.

A culture method for the isolation and identification of penicillinase (beta-lactamase)-producing Neisseria gonorrhoeae (PPNG) was evaluated in the Philippines where PPNG are common. The method uses plastic biplates containing standard Martin-Lewis gonorrhea culture medium in one side of the biplate and PPNG-selective medium containing 1.5 microgram of penicillin G per ml and a suspension of Sarcina lutea (Micrococcus lutea) that was susceptible to 0.01 microgram of penicillin G per ml in the other side. Penicillin-resistant gonococci grow on both sides of the biplate. The hydrolysis of penicillin by beta-lactamase permits the growth of S. lutea around PPNG colonies. With this medium we successfully identified 11 of 12 PPNG strains growing on primary isolation plates. A 48- to 72-h incubation period was needed, however, for visible growth of S. lutea around PPNG colonies. A unique advantage of this method was the identification of non-PPNG strains which also grew on penicillin-containing medium but did not allow growth of S. lutea. These relatively penicillin-resistant strains were the cause of infections which were not cured by penicillin treatment in 2 of 11 patients.

Culture Media↗
PubMed1980

Evaluation of the phadebact gonococcus test, a coagglutination procedure for confirmation of Neisseria gonorrhoeae.

Rapid and accurate immunological confirmation of presumptively positive gonococci could be facilitated with the Phadebact Gonococcus Test, a slide coagglutination procedure. The test was compared with carbohydrate utilization and fluorescent-antibody tests on 235 clinical isolates. With the coagglutination procedure, 97.1% of the isolates were identified as compared with 93.1% by carbohydrate utilization and 98.7% by fluorescent antibody. The Phadebact test was highly specific, showing no cross-reactions with 55 other Neisseria species or with 50 miscellaneous organisms occasionally found growing on selective culture media. Because of its high sensitivity and specificity, ease of performance, and ability to provide results in 2 to 3 min, this procedure provides a suitable alternative to the carbohydrate utilization and fluorescent-antibody tests for confirmation of N. gonorrhoeae.

Agglutination Tests↗