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Biomedical subjects

J Roux

Publications and source records attributed to J Roux.

At least 127 records · Page 7Linked to original sources
PubMed1981

[Epidemiology of Brucellosis. Trial evaluation of the incidence of clinical and infraclinical forms (author's transl)].

The incidence of clinical and infraclinical human brucellosis was estimated by survey undertaken in 1976 on a representative sample of the population of the Vaucluse (France) district. It is shown that, by combining research of late hypersensitivity and serologic tracking in 2084 individuals, the incidence of diagnosed clinical brucellosis, in the Vaucluse district is at least 3 to 5 times more important than the incidence evaluated by the official notifications, and that there are 10 times more infraclinical or non diagnosed brucellosis than diagnosed brucellosis. The results show the need of triple investigation by interview, serology and hypersensitivity test (complementarity of the three technics) so as to evaluate the true morbidity of this anthropozoonosis.

Adolescent↗
PubMed1980

The effect of estrogen priming on induction of labor with prostaglandins.

A double-blind, randomized study was designed to determine whether estrogen "priming" of the unripe cervix followed by prostaglandin induction of labor would have a synergistic effect on cervical ripening and improve the success rate of induction. One hundred near-term patients with Bishop scores less than or equal to 4 received an intramuscular injection of either 10 mg of estradiol valerate or a placebo 48 hours prior to induction of labor with oral prostaglandin E2. The serial changes in Bishop scores were very similar in both groups. The success rate of induction in the study group (69.8%) was not statistically different from that in the control group (61.9%). The duration of labor was 9.9 +/- 4.1 hours in the study group versus 9.1 +/- 3.7 hours in the control group (not significant). This study showed that 10 mg of estradiol valerate had no detectable effect on the unripe cervix near term and did not show a synergistic effect with prostaglandins during induction of labor.

Adult↗
PubMed1980

In vitro conversion of pregnenolone to progesterone by term human fetal membranes.

The conversion of pregnenolone to progesterone by homogenates of term human fetal membranes (38 to 40 weeks' gestation) was quantitated prior to and after labor. Chorion pars reflexa obtained after spontaneous labor by vaginal delivery was more active than that obtained prior to labor by elective cesarean section (p less than 0.05). With homogenates of amnion pars reflexa (n = 18), and pars placentaris (n = 18) obtained prior to labor no conversion or pregnenolone to progesterone was detected. In contrast, in amnion pars reflexa obtained after labor the reaction was detected in five of the 13 tissues examined and was significantly different from tissues obtained prior to labor (p less than 0.01). However, the conversion by the amnion pars placentaris after labor was not significantly different from that to labor. Evidence for inhibition of the reaction in the amnion pars reflexa and pars placentaris obtained prior to labor was found when prolonged washing of these tissues (up to 5 hours) with isotonic KCl resulted in the conversion of pregnenolone to progesterone being easily detected. This study suggests that there may be "activation" of the conversion of pregnenolone to progesterone in fetal membranes during labor and indicates that considerable care should be taken in studying this and perhaps other reactions in fetal membranes as the mode of delivery, the preparation of tissue, and, in the case of the amnion, the area studied can affect the results obtained.

Amnion↗
PubMed1980

[Ultrasonic topographical study of pancreatic vascular relationships; I. Splenic vein, SMA, SMV, celiac trunk (author's transl)].

Sonography, a "dissection on the living patient", displays many topographical variations, of whom several are usually not depicted in classical textbooks of anatomy. Sonographic and angiographic studies disclosed the following results: the splenic vein is running above the AMs origin (34%), at the same level (7%), or below (59%). The SMA originates at a distance of 5 to 45 mm of the CT origin. The SMV is running on the right, on the left or in front of the SMA. Such variations must be kept in mind when analysing the morphology and rich vascular relationships of the pancreas.

Celiac Artery↗
PubMed1979

[The treatment of brucellosis using rifampicine (author's transl)].

The authors discuss the present value of rifampicin in the treatment of human brucellosis on the basis of: 1) a bacteriological study of 42 strains of Brucella spp. (MIC's of rifampicin, tetracyclin, doxycyclin, minocyclin and streptomycin; results of doxycyclin-rifampicin and doxycyclin-streptomycin combinations), and 2) a clinical study of 38 cases of brucellosis treated with rifampicin, including 25 acute septicemias and 13 osteo-arthritis. Satisfactory results were observed in 92% of the cases with rifampicin alone, but one cannot state that the benefits are significant.

Acute Disease↗
PubMed1979

[Betablockers and skin (author's transl)].

Up to now betablockers, with the exception of erythermalgia, have been rarely used as therapeutic agents in dermatology. However, cutaneous drug reactions are numerous. A review of the literature about practolol cutaneous effects and their possible mechanisms has shown that a great variety of clinical states can be encountered. All betablockers have been known to produce harmful side effects, although less frequently. In conclusion, the description of each new case of cutaneous drug reaction probably due to betablocker must be assessed.

Adrenergic beta-Antagonists↗