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Biomedical subjects

J Remy

Publications and source records attributed to J Remy.

At least 109 records · Page 6Linked to original sources

[Systematised interstitial emphysema in neonatal respiratory distress. Four cases (author's transl)].

Localisation in one lung only or in one lobe only of lesions of interstitial emphysema is surprising in a diffuse disease such as hyaline membrane disease in premature infants. In the four patients in which this unusual course was seen, cure was obtained in different ways: spontaneously in one case, by excision of a diseased lobe in two cases and by selective temporary intubation of the contralateral main bronchus in the final case. Current methods of treatment of neonatal respiratory distress favour this type of course, without any precise cause being evident. Excision surgery is often avoidable by transient ventilation of the contralateral lung only by selective intubation of the main bronchus.

Emphysema↗

Ultrasound diagnosis of extrahepatic portal vein obstruction in childhood. The sign of the subhepatic sponge-like mass.

Portal vein obstruction in childhood produces portal hypertension and hepatopetal collaterals surrounding the obstructed portal vein; this is the "cavernomatous transformation of the portal vein" which is a well defined angiographic entity. Clinically findings are the various manifestations of Banti's syndrome, especially splenomegaly and gastrointestinal bleeding. Ultrasonic diagnosis is possible on the associated findings of splenomegaly, normal liver, a subhepatic sponge like mass corresponding to the hepatopetal collaterals. These signs must be sought in the ultrasonic differential diagnosis of splenomegaly in pediatrics.

Child↗

Distribution of tritium in the different organs of calves and pigs after ingestion of various tritiated feeds.

A research programme on the transfer of tritium in the food chain has been in progress for several years on the experimental farm of the Nuclear Energy Research Center at Mol. The studies reported here are related to the distribution of tritium in the organs of farm animals contaminated in various ways. Two young male calves ingested tritiated milk; the daily intake of 3H-organic form was about 15 muCi for each calf and the total activity ingested until the sacrifice was 482 muCi. Three male pigs from the same litter and about 7 weeks old were used for each experiment on the administration of tritium under different forms: (a) single intraperitoneal injection of 39.3 mCi HTO (P2, P3, P4). (b) daily ingestion of 28.4 muCi HTO. The total activity ingested was respectively 569 muCi (P5) and 766.8 muCi (P6). (c) ingestion of tritiated potatoes. The total activity ingested was respectively 21 muCi (P8), 40.3 muCi (P9) and 48.1 muCi (P10). (d) ingestion of tritiated milk powder. The total activity ingested was respectively 60.6 muCi (P13), 110.4 muCi (P11) and 154.5 muCi (P12). After slaughtering of each animal various organs were removed and analyzed for the 3H content in the tissue water and in the organic matter. We could verify that the chemical form of 3H present in the food is of great importance for the incorporation of 3H in the organic matter of the animal organs. The total incorporation increases by a factor 5.6 when 3H is ingested as tritiated milkpowder by pigs as compared to HTO and with a factor 15 for calves. When tritiated potatoes were ingested by pigs a factor 15.6 was found. The transfer of 3H from HTO and milk feed ingested in the organic fraction of organs is lower for pig than for calf. When we consider the 3H in the tissue water of organs the specific activity (SA) is a little lower than the SA of ingested HTO and after ingestion of tritiated milk feed the activity is very low and no difference due to the species is found. After fractionation of liver and spleen tissue following the technique of Schmidt--Thannhauser radioactivity was found in all liver and spleen constituent lipids--RNA--DNA and proteins, but after isolation and purification of DNA following the original methods, we have not been able to demonstrate that tritium is really incorporated into DNA molecules of a non-dividing organ such as the liver nor of an actively dividing organ such as the spleen.

Animal Feed↗

[Effect of acute irradiation on the exocrine secretion of pancreas in pig].

Six fistulated pigs have been used in this experiment to study the effect, on the exocrine pancreatic secretion, of a partial acute irradiation, at 600 rd and 800 rd. Whatever the dose, the irradiation provoked an immediate and temporary decrease of the pancreatic secretion. The normal values were reached after the 8th day post-irradiation. Furthermore, a direct effect on the synthesis of amylase and lipase was shown. The synthesis of trypsin and chymotrypsin was not modified by irradiation.

Amylases↗