Biomedical subjects
J Remy
Publications and source records attributed to J Remy.
Spontaneous rupture of the esophagus in the newborn.
Two cases of neonatal spontaneous rupture of the esophagus are described, one of which is associated with a duodenal stenosis. Seventeen cases have been reported. They present clinically with non-specific signs of respiratory insufficiency and radiologically by a right-sided hydropneumothorax. Esophageal opacification shows a leak above the diaphragm. A sudden increase in esophageal pressure at birth is considered to be a major etiologic factor leading to rupture. The presence of a duodenal obstruction support this hypothesis.
In vitro growth potential of fibroblasts isolated from pigs with radiation-induced fibrosis.
Degenerative processes were studied in pig muscles irradiated with single doses of 30 or 40 Gy. Damaged muscle was gradually replaced by an invasive fibrotic tissue. As a control, surgical muscle exeresis was performed of the same size as the radiation-induced lesions at the same anatomical site. Primary cultures were set up comprising cells freshly extracted from normal dermis, or from tissue exhibiting either normal wound fibrosis or radiation-induced fibrosis. The growth potential of cells taken from the latter region far exceeded that of the two other types; attachment efficiency was higher, and fibronectin was detected early by immunofluorescence. These in vivo and in vitro observations imply that a pathological repair process occurs after localized irradiation.
Segmental bronchovascular anatomy of the lower lobes: CT analysis.
A systematic evaluation of the anatomic relationships of the segmental bronchi, arteries, and veins of 107 right and 113 left lower lobes was made from CT scans of patients with normal chest radiographs. The classic taxonomies of Boyden and Jackson and Huber were used for nomenclature. Identification of individual structures was based primarily on careful analysis of contiguous CT slices. The frequency of identification of each of the major segmental bronchi and their corresponding arteries was established, and variations in the number and position of arteries were recorded at four transverse levels on the right side and three levels on the left side. The segmental venous tributaries of the inferior pulmonary vein were also identified. Although there is considerable constancy in the anatomy of the lower lobe segments, variation from the dominant pattern occurred in as many as 20% of cases. Sometimes major segmental bronchi were not identified and presumably varied in their origin. The segmental arteries may be single, duplicate, or even triplicate. Within the segments, the arteries generally lie toward the lung periphery relative to their corresponding bronchi, thus being anterior, lateral, or posterior. The segmental veins generally lie central to their bronchi, thus being posterior, medial, or anterior. Knowledge of prevailing patterns and variant appearances of the lower-lobe vascular structures can be helpful in interpreting CT scans. Such knowledge is a prerequisite for the identification of pulmonary nodules in the vicinity of vascular structures and the recognition of intersegmental lymph nodes and aberrant vessels.
Development of lesions resulting from acute localised irradiation in the pig: trials for medical and surgical management.
Explore the source record for details and available documents.
Radiosensitivity of pig fibroblasts. In-vitro clonal growth assay.
Explore the source record for details and available documents.
In-vitro growth potential of fibroblasts isolated from pigs with radiation-induced fibrosis.
Explore the source record for details and available documents.
Drug-induced torsade des pointes: case report and implications for the critical care staff.
Explore the source record for details and available documents.
[Incidence of hepatitis B virus infection in the medical personnel of physicians' offices].
Serological examination to determine anti-HBc antibodies in 1487 medical personnel working with practitioners in Essen revealed a hepatitis B virus incidence rate of 12.8%. The incidence rate depended on age, years of service, and nature of duties. Anti-HBc examination of medical personnel is cost-saving in view of high cost of vaccination. It can be omitted only in beginners if certain conditions are fulfilled (anti-HBc rate below 5%).
Radiosensitivity of swine lymphocytes: in vitro modifications of the cell cycle and kinetics of the appearance of chromosomal aberrations.
gamma-Radiation-induced modifications of the cell cycle of swine lymphocytes have been studied by the harlequin chromosome technique and by the uptake of tritiated thymidine. The radio-induced mitotic delay is 1 h per Gy. This delay occurs mainly in the lengthening of the initial phase prior to the first mitosis. The gamma-ray dose-response curve for dicentrics in first-division cells has been studied after different durations of culture. The radio-induced mitotic delay varied within the lymphocyte population: the mitosis commences much later as the cells exhibit a greater number of anomalies (dicentrics). The dose-effect relationships which can be established are thus closely conditioned by the duration of the culture. The mitotic delay observed in irradiated swine lymphocytes could amount to a restoration phase of duration varying with the importance of the induced damage.
Massive hemoptysis of pulmonary arterial origin: diagnosis and treatment.
Among 189 patients treated for massive or repeated hemoptysis by transcatheter techniques between 1973 and 1983, a prospective study was attempted between 1979 and 1983 (72 patients) to search for bleeding of pulmonary arterial origin. Among these 72 patients, six were treated by surgical (one) or angiographic (five) occlusion of segmental pulmonary arteries. Pulmonary erosive pseudoaneurysms were seen in five cases (one with intracavitary aspergilloma, two with cavitary tuberculosis, and two with pyogenic abscesses). Among these six cases, one patient died from massive hemoptysis, one from unknown causes, and four are still alive. They are compared with five other patients who died from massive hemoptysis among 117 patients treated only by embolization of their systemic arteries between 1973 and 1979 (one with cavitary tuberculosis, two with intracavitary aspergillomas, one with an abscess of the lung, and one with a necrotic hilar cancer). A pulmonary arterial source of bleeding should be considered in addition to systemic arterial sources in the setting of destructive lung disease.
Carpal and tarsal osteolysis.
This report describes the symptoms, clinical course and radiological features in three cases of idiopathic carpotarsal osteolysis. Before signs of extensive osteolysis were noted, one of our patients showed flattening, loss of harmonious curvature and minimal osteoporosis of carpal and tarsal bones, all early radiological signs which have not been described previously. We discuss the findings, classification and our ideas as to the cause of the disorder.
[Therapeutic applications of angiography in pneumonology].
Explore the source record for details and available documents.
Modes of intestinal cholesterol absorption in adult sows.
The nature and distribution of neutral sterols has been determined in the digestive tract of adult Large White sows maintained in a defined biological steady state (constant weight: 70 +/- 5 kg). The semi-synthetic diet contained 0.08 p. 100 cholesterol. Cholesterol was the main sterol of the intestinal contents. From the caecum, it was partially transformed into coprostanol (less than 6 p. 100). Just before the morning meal, the intestinal contents of the sows were rich in cholesterol (532 mg in the small intestine). As in rats, this rapidly renewed cholesterol of endogenous origin was not distributed homogeneously with the exogenous dietary cholesterol. During intestinal cholesterol transit, hydrolysis exceeded esterification. Using the principle of occupancy of every dynamic system, two isotopes were employed to measure the absorption coefficient: cholesterol-4-14C (10 microCi), incorporated into the meal and ingested at one time, and cholesterol-3H (400 microCi), injected intravenously once in a suspension of autologous red blood cells previously labelled in vitro. The absorption coefficient of dietary cholesterol in our experimental conditions reached 57 +/- 4 p. 100. The cholesterol was mainly absorbed in the first-half of the small intestine as in man, whereas in rat it is absorbed in the second-half. This dietary tracer appeared in the general circulation later in swine than in rat or man. After intake of a meal containing the cholesterol tracer, maximal plasma cholesterol radioactivity was reached after 48 hrs in the sows while it is reached after 10-12 hrs in rat or man.
Allograft tolerance in pigs after fractionated lymphoid irradiation. I. Skin grafts after partial lateral irradiation and bone marrow cell grafting.
Explore the source record for details and available documents.
[Topographic radiologic anatomy of the right subcarinal and retrobronchial pulmonary recess (author's transl)].
Depending on the size of the subcarinal and retrobronchial recess the medial wall of the right and perhaps the left main bronchus can be recognized. The medial extension of the recess is very variable. On lateral films with slight anterior rotation of the right shoulder, the posterior wall of the right main bronchus can be shown in 97% of patients. Awareness of this recess and its boundaries is essential for diagnosis of subcarinal and tracheobronchial node enlargement. The following 4 signs will assist in diagnosis: 1. The dorsal margin of enlarged nodes may be recognized posterior and inferior to the carina. 2. The posterior wall of the right main bronchus can no longer be seen. 3. The medial wall of the right main bronchus can no longer be seen. 4. Clearer demonstration of the right main bronchus or bronchus intermedius occurs, due to an "air bronchogram" effect. Due to the application of these 4 signs, enlargements of the subcarinal or tracheobronchial nodes can be recognized, at a stage where the tracheal bifurcation is not yet splayed, and when the nodes have not yet caused bronchostenosis.
[Systemic vascularization in thoracic pathology].
Explore the source record for details and available documents.