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Biomedical subjects

J R Woodside

Publications and source records attributed to J R Woodside.

At least 73 records · Page 4Linked to original sources

Urodynamic evaluation of dysfunctional bladder neck obstruction in men.

Dysfunctional bladder neck obstruction in young men has received increasing interest in recent years. The urodynamic characteristics of this disorder include elevated voiding pressure, normal reflex relaxation of the urethral rhabdosphincter, increased pressure gradient between the membranous urethra and the bladder, and inadequate radiographic bladder neck opening during detrusor activity. The functional changes occurring at the internal sphincter in 3 patients with dysfunctional bladder neck obstruction are described herein. It is demonstrated that the obstruction may result from either an active dyssynergic bladder neck contraction or failure of bladder neck relaxation. While the pathophysiology of dysfunctional bladder neck obstruction is uncertain possible mechanisms are discussed.

Adult↗

Urinary tract undiversion in a patient with an areflexic neurogenic bladder: management with intermittent catheterization.

Neurogenic bladder disease generally is though to be a contraindication to urinary undiversion. We describe a teenage boy who received an ileal conduit for an areflexic neurogenic bladder. He had a poor emotional reaction to the diversion and requested reconstruction. After extensive studies undiversion was done. The neurogenic bladder has been managed with intermittent catheterization. Thus far, the result has been quite satisfactory.

Adolescent↗

Dissolution of vesical calculi with Renacidin in a paraplegic man.

Vesical calculi are common in spinal cord injury patients. The majority are composed of magnesium ammonium phosphate, a compound readily soluble in the solvent Renacidin. We describe a paraplegic man with recurrent bladder stones in whom cystolitholopaxy was unsuccessful. His calculi were completely dissolved by continuous Renacidin bladder irrigation. We recommend Renacidin for the initial treatment of vesical calculi in selected spinal cord injury patients. Many such stones will completely dissolve and others may be made softer or smaller, facilitating cystolitholopaxy. A significant number of patients will be spared the inconvenience, cost and morbidity of hospitalisation for a surgical procedure.

Adult↗

The pressure-flow relationship of the normal ureter.

We performed ureteral pressure-flow studies in 10 patients, all of whom had radiographically nondilated ureters and were undergoing a surgical procedure in which the ureter was exposed. The mean ureteral pressures at perfusion rates of 2, 5, 10, and 15 ml per min were 6.2, 7.9, 11.3, and 13.7 cm of water respectively. The mean pressures at each perfusion rate significantly differed from each other, except those at 2 and 5 ml per min. A statistically linear relationship exists between pressure and perfusion rates within the range of 2 and 15 ml per min.

Adolescent↗

Sertoli cell tumor (gonadal stromal tumor) in an infant.

An 8-mo-old boy had an orchiectomy for a Sertoli cell tumor. Malignancy was suspected histologically. He underwent a retroperitoneal lymphadenectomy and no nodes contained metastases. The histologic criteria for malignancy in Sertoli cell tumors are controversial. Individual case reports of patients with these tumors are encouraged to help establish their natural history and optimum management.

Adult↗

Spinal hematoma compressing cauda equina.

Epidural and subdural spinal hematomas are unusual complications of diagnostic lumbar punctures. A renal allograft recipient on anticoagulant therapy underwent lumbar puncture. Urinary retention and evidence of an S2, S3, and S4 neurologic deficit developed subsequently. A myelogram showed a defect of the posterior lumbosacral spinal canal. Urodynamic investigation demonstrated normal sympathetic innervation of the proximal urethra and impaired parasympathetic and pudendal innervation of the detrusor and external urethral sphincter, respectively.

Adult↗

Management of bladder diverticula by transurethral resection: re-evaluation of an old technique.

Many surgical techniques have been described for bladder diverticulectomy, including extravesical, intravesical or combined procedures. An alternative therapeutic technique not widely recognized is transurethral resection of the diverticular neck. We have used this procedure on 6 patients, either to promote emptying of a diverticulum or to permit adequate endoscopic examination. Each operation was successful and there were no complications. We herein describe this technique and recommend its use in selected patients.

Aged↗

A simple inexpensive urodynamic catheter.

Described herein is an easily constructed and inexpensive triple lumen urodynamic catheter. The catheter permits accurate and reproducible simultaneous measurements of urethral and bladder pressure.

Child↗

Urethral hypotonicity after suprasacral spinal cord injury.

Established suprasacral spinal cord injuries usually are associated with detrusor hyperreflexia and varying degrees of detrusor-sphincter dyssynergia. Occasionally, such injuries result in detrusor areflexia or urethral hypotonicity or both. The results of the urodynamic evaluation of 4 patients with suprasacral spinal cord injuries are described. Detrusor areflexia and urethral hypotonicity were demonstrated in 3 cases and urethral smooth muscular hypotonia but preserved reflex detrusor function in 1. It is shown that destruction of the thoracolumbar sympathetic outflow can cause the complete loss of urethral smooth muscular closing function and that resting urethral closure is totally independent of preganglionic cholinergic influences.

Adult↗

Immunoglobulin in urine from ileal conduit and nephrostomy patients.

Patients with ileal conduits frequently have bacteruria, and some have pyelonephritis with associated renal deterioration. We attempted to find a noninvasive technique that could be used to define the source of the bacteria in such patients. Neither the antibody-coated bacteria test nor the selective immunofluorescent antibody studies made this distinction. Quantitative immunoglobulin determinations performed on urine from ileal conduits containing either less or greater than 10(5) bacteria per ml showed IgA to be the predominant immunoglobulin. Urine from patients with permanent nephrostomy drainage who had known chronic upper urinary tract infection contained predominantly IgG. Inasmuch as several studies have shown that both normal urine and urine from patients with pyelonephritis contain more IgG than IgA, we conclude that the conduit added IgA to the urine. However, even this quantitative immunoglobulin technique is unable to identify the source of the bacteria. To do so would have required an invasive collection of upper tract urine. The occurrence of acute symptomatic pyelonephritis was rare during the 18 months of the study, but the urine of the one ileal conduit patient with acute pyelonephritis studied contained more IgG than IgA.

Antibodies, Bacterial↗

Antibody-coated bacteria in urine of patients with ileal conduit urinary diversion.

The antibody-coated bacteria (ACB) test is a helpful adjunct for differentiating pyelonephritis from cystitis in the intact urinary tract, particularly in female patients. This test was used in patients with ileal conduits and infected urine in an attempt to determine whether bacilluria was of renal or conduit origin. Every patient with infected conduit urine had a positive ACB test even though no patient had clinical stigmas of acute pyelonephritis. In patients with ileal conduits, the ACB test cannot be used alone as an indicator that bacilluria is a cause of symptoms or renal damage.

Adolescent↗

Perirenal malignant Schwannoma presenting as renal cell carcinoma.

Clinical and radiographic evaluation of a fifty-six-year-old male with microscopic hematuria led to radical nephrectomy for renal cell carcinoma. Histologic examination by light and electronmicroscopy was most compatible with malignant schwannoma. The tumor was close to the kidney without actual renal involvement. This case is of interest for both its rarity and its unusual presentation.

Carcinoma↗