Search PubMed⌕ Search

Biomedical subjects

J R Coppeto

Publications and source records attributed to J R Coppeto.

48 records · Page 3Linked to original sources
PubMed1984

Orbitocalvarial swelling and proptosis as an early manifestation of systemic lymphoma.

A 67-year-old woman had acutely diminished vision and painful proptosis of the left eye amidst a background of chronic headache, scalp tenderness, proximal myalgias, intermittent fever, anemia, and elevated erythrocyte sedimentation rates. All symptoms and signs were exquisitely corticosteroid-responsive. She underwent two negative temporal artery biopsies and several extensive negative evaluations for systemic disease. Ultimately deep scalp biopsy, bone biopsy, and bone marrow aspiration were performed, and all revealed a histologically well-differentiated lymphoma.

Aged↗
PubMed1983

Downbeat nystagmus. Long-term therapy with moderate-dose lithium carbonate.

Downbeat nystagmus developed in a 67-year-old hypomagnesemic woman while she was receiving lithium carbonate for depression. This nystagmus abated each time lithium carbonate therapy was withdrawn, and no alternative causes of nystagmus were demonstrated. However, this nystagmus occurred despite serum lithium carbonate levels in the nontoxic range. Total-body magnesium deficiency may have enhanced the toxic effect of lithium carbonate on cerebellomedullary connections.

Aged↗
PubMed1983

Foster-Kennedy syndrome caused by solitary intracranial plasmacytoma.

The first case of typical Foster-Kennedy syndrome, including decreased olfaction of the side of the optic atrophy due to a primary solitary intracranial extraskeletal plasmacytoma, is reported. Its appearance on a computed tomography scan was compatible with a meningioma or subdural hematoma. The patient demonstrated a chronic, corticosteroid-sensitive, relapsing optic neuropathy associated with an elevated sedimentation rate and a monoclonal gammopathy. The diagnosis, treatment, and prognosis of such tumors are reviewed.

Brain Neoplasms↗
PubMed1983

Dorsal midbrain syndrome from giant aneurysm of the posterior fossa: report of two cases.

Two patients with giant posterior fossa aneurysms compressing the upper ventral brainstem presented principally with findings referable to the dorsal midbrain (upgaze paralysis and lid retraction). We hypothesize that the signs were produced by kinking of the upper brainstem, thus compressing the dorsal midbrain against the free edge of the tentorium of the cerebellum.

Aged↗
PubMedDate not supplied

Astrocytic hamartoma in tuberous sclerosis mimicking necrotizing retinochoroiditis.

A pale, elevated peripapillary lesion discovered in a young child with no family history of phakomatoses, grew larger, caused vitreous hemorrhage and underwent necrosis. Secondary inflammation developed in the eye, finally producing rubeosis irides with elevated intraocular pressure and a blind, painful eye which required enucleation. Clinically, the lesion was variably diagnosed and treated as toxoplasmosis and toxocara canis. These diagnoses were made despite low titres, a negative ELISA test and a normal eosinophil count. On histopathologic examination, a diagnosis of toxocara canis was entertained, although no remnants of the organism could be found in serial sections. Years later, when a family history of tuberous sclerosis became apparent, a diagnosis of astrocytic hamartoma of the retina with secondary hemorrhage and inflammation was made on the basis of re-examination of the pathologic specimen and special stains.

Adult↗