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Biomedical subjects

J Prevot

Publications and source records attributed to J Prevot.

At least 37 records · Page 2Linked to original sources

[Contribution of MRI to the diagnosis of double aortic arch].

The authors present a case of double aortic arch explored by MRI and discuss the advantages and disadvantages of MRI as compared to other noninvasive imaging methods, such as ultrasounds and digital angiography, in congenital pathology of the aorta. Because it provides good quality images, can explore the aorta in all three dimensions, has optimal vascular contrast without contrast injection and carries no risk, MRI is indispensable in all cases where ultrasonography finds its limitations. Besides, the subjective factor inherent in the operator is very small, and MRI is the best available method to study the relations between the aorta and the surrounding organs; this is particularly important in case of double aortic arch owing to compression of the neighbouring organs with, notably, stridor. However, the vascular map is less accurate than with angiography, and the cost, the problem of access to the machines and the long time required for acquisitions limit the use of MRI.

Aorta, Thoracic↗

[Study of distraction osteogenesis in an animal body submitted to anticancer chemotherapy].

The authors studied distraction osteogenesis in an animal subjected to prolonged anti-mitotic chemotherapy (Methotrexate and Doxorubicin). This chemotherapy decreased osteogenesis (essentially at the expense of external regeneration) though without inhibiting it totally. Distraction bone consolidation is thus possible in the animal, permitting reconstruction of limb segments by mobilization of an axial fragment in accordance with the Ilizarov technique.

Animals↗

[Cubital dimelia. Apropos of a case with review of the literature].

Cubital or ulnar dimelia is a very rare congenital abnormality involving almost perfect duplication of the ulnar with absence of the radius, thumb and polydactyly. An eleven week old child was seen in the Department of Pediatric Surgery for a malformation of the left upper limb including deformity of the forearm with almost doubling of the hand and seven fingers. Radiological investigation revealed duplication of the ulna as well as of the metacarpals and fingers with absence of the radius and thumb. This type of abnormality remains controversial but clinical and radiological examination led to the conclusion of primary ulnar dimelia. We report a new case of this very rare congenital abnormality which was not accompanied by any other malformation.

Hand Deformities, Congenital↗

[Unusual forms of upper femur epiphysiolysis].

Among 56 slipped capital femoral epiphysis (SCFE) treated over 12 years, the authors report 10 particular cases: 3 hypopituitarisms, 1 adrenal hyperplasia, 1 case after radiotherapy, 2 osteochondrodysplasia, 2 cases with major defect of the posterior wall of femoral neck and 1 coxa valga slip. Literature is analysed with special reference to etiological forms representing a predisposition to slippage. Awareness of these conditions under which SCFE can occur is an important factor. Surgical stabilization is classical, but two points are discussed: stabilization may need to be augmented by autologous bone grafting or to be fixed with pins leading to normal growth without dysplasia of the hip.

Adolescent↗

Pulmonary sequestrations of the upper lobe in children: three presentations.

Pulmonary sequestrations are congenital abnormalities where nonfunctioning lung tissue receives its vascular supply from the systemic circulation (thoracic or abdominal aorta). It is necessary to establish the diagnosis in childhood when the lesions are uncomplicated. The authors present three cases of sequestration of the apex (2 extralobar and 1 atypical) with the main clinical and radiological features. Sequestrations in the upper lobe are rare, and the usual site is the left lower lobe. Plain x-rays show a dense opacity, sometimes air-filled and sometimes with an air-fluid level: angiography is currently the best mean for definitive diagnosis; however, computed tomography will probably be very useful in the future. Differential diagnosis includes tumours of the superior mediastinum (neurogenic tumours, digestive duplication, bronchogenic cysts, pheochromocytoma and hydatid cysts).

Angiography↗

[Lengthening osteotomy of the femoral neck with transposition of the greater trochanter in acquired coxa vara].

The main problem in acquired coxa vara is related to shortening of the femoral neck and upward displacement of the greater trochanter. Using the Wagner technique, the authors have performed an intertrochanteric osteotomy in five adolescents with transfer of the greater trochanter to lengthen the femoral neck. The technique is described. The early results are encouraging.

Adolescent↗

[Legg-Perthes-Calvé disease. Plea for an original ambulatory orthosis].

Legg-Perthes-Calvé disease is a local disease which should be treated by non-iatrogenic means. The authors have designed a new ambulatory orthosis allowing containment in abduction, flexion and medial rotation, with relief of weight-bearing on the femoral head. It was tested in thirty six hips. In only eight of them a surgical procedure had to be performed during the evolution of the disease (femoral or pelvic osteotomy) because of secondary exenteration of the hip.

Child↗

Rotavirus carriage, asymptomatic infection, and disease in the first two years of life. I. Virus shedding.

From September 1979 to July 1980 inclusive, rotaviruses were prospectively detected by electron microscopy (EM) and ELISA in 82 (29%) of 283 children under two years of age who were admitted to a general pediatric ward in Paris. Rotavirus was found in 43 (36%) of 119 children with diarrhea and in 40 (24%) of 164 children without diarrhea; thus of 83 children shedding rotavirus, 40 (48%) were not diarrheic. Virus shedding that was not associated with diarrhea was observed in 71% of neonates, in 50% of one- to six-month-old children, and in 26% of 7-24-month-old children. Rotavirus shedding was statistically correlated (P less than .01) only with those cases of diarrhea with fever and vomiting ( DFV syndrome). Consequently, relative risk (RR) for the DFV syndrome in patients who were shedding virus was 2.07 (P less than .001) vs. 0.95 for other types of diarrhea. These observations show that asymptomatic rotaviral infection is not an infrequent occurrence; that the association between rotavirus and diarrhea is not necessarily an etiologic one; and that the DFV syndrome appears as a major clinical expression of rotaviral disease. Consequently, recovery of rotavirus from feces is of little diagnostic significance since it does not give a differentiation between rotavirus-induced and rotavirus-associated diarrhea.

Aging↗

Rotavirus carriage, asymptomatic infection, and disease in the first two years of life. II. Serological response.

Serological response to rotavirus and virus shedding were prospectively studied in 179 children (neonatal to 24-month-old) upon admission to a hospital during an 11-month period. Analysis of the evolution of IgG and IgM ELISA titers revealed 24 cases of rotaviral disease (serological response and diarrhea), 13 cases of asymptomatic infection (serological response and no diarrhea), 36 cases of virus carriage (absence of a serological response), three cases of past infection, and six possible cases of nosocomial infection. Rotaviral disease was encountered two out of three times and was characterized by diarrhea associated with fever and vomiting. Asymptomatic rotaviral infection and disease, observed from the neonatal period onwards, affected 2% of neonates, 20% of one- to six-month-old children, and 37% of 7-24-month-old children. In contrast, virus carriage occurred in 27%, 19%, and 14% of those children respectively. Altogether these results indicate that during the period 1-24 months of age, when asymptomatic rotaviral infection and disease were prevalent, approximately two of 10 children had rotaviral disease, one of 10 had asymptomatic infection, two of 10 were virus carriers, and five of 10 were not infected with rotavirus.

Aging↗

[Congenital giant diverticuli of the bladder. Apropos of 3 cases].

The giant congenital vesical diverticulum of the bladder is very uncommon; three observations are described. The clinic symptomatology is ruled by acute retention of urine and by dysuria. The I.V.P. always shows the important reverberation on the renal cavities. In two cases the diagnosis has been done thanks to the cystography. Concerning the third child both clinic and paraclinic symptoms inclined to favour the diagnosis of an abdominal cystic hygroma but the surgical procedure showed it was a bilateral vesical diverticulum. The surgical treatment is made up of endo and latero-vesical diverticulectomy with reimplantation of the homolateral ureter which is always implanted in the posterior pouch. With its clinical, anatomical and physiopathological aspects, the giant congenital diverticulum of the bladder must be differentiated with the little diverticulum.

Child, Preschool↗