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Biomedical subjects

J Pinkhas

Publications and source records attributed to J Pinkhas.

At least 199 records · Page 11Linked to original sources
PubMed1980

Aortic stenosis associated with gastrointestinal bleeding. A survey of 612 patients.

A retrospective study was done in order to examine the association between aortic stenosis (AS) and gastrointestinal tract (GIT) bleeding. Four groups of patients included a group of 152 patients with AS, a control group of 152 patients with MS, and another two groups of 154 patients each with and without GIT bleeding. GIT bleeding of known and of idiopathic sources was significantly more prevalent among patients with AS (three and four patients, respectively) than among those with MS (none). Moreover, AS was significantly more prevalent in association with idiopathic GIT bleeding (seven out of 24, 29.1%), in comparison to its association with bleeding from a known source (two out of 130, 1.5%), and its incidence in routinely admitted patients without GIT bleeding (three out of 154, 1.9%). This study supports the assumption that GIT bleeding may be associated with AS.

Adolescent↗
PubMed1980

A hypothesis on the possible role of interferon in the initiation of acute gouty arthritis attack.

There is some evidence that unidentified factors might play a role in the initial events of acute gouty arthritis. Serum interferon activity was found to be high in several arthritides; interferon stimulates the production of prostaglandin E, an established mediator of inflammation. It is postulated that interferon can play a role in the pathogenesis of an acute gouty arthritis.

Acute Disease↗
PubMed1980

Diagonal ear lobe crease and coronary risk factors.

The prevalence of ear lobe crease (ELC) was determined in 421 patients with myocardial infarction (MI) and in 421 controls. A higher prevalence (p less than 0.05) of ELC was found in MI patients (77 percent) in comparison to controls (40 percent), regardless of age. In addition, a higher prevalence was found in patients in whom MI was combined with diabetic retinopathy or hypertension, and in Ashkenazi Jews compared to non-Ashkenazi Jews. Ear lobe biopsies in 12 subjects revealed tears of the elastic fibers in all subjects with ELC, and prearteriole wall thickening in subjects with MI and/or ELC, but not in the 2 subjects with neither MI nor ELC. The early appearance of ELC may imply the existence of coronary heart disease with or without coronary risk factors.

Adult↗
PubMed1980

Salazopyrin-induced eosinophilic pneumonia.

A patient with ulcerative colitis developed eosinophilic pneumonia, sinus tachycardia, skin rashes, headache and insomnia following treatment with Salazopyrin. The pneumonia as well as the other side effects resolved spontaneously following discontinuation of the drug and reappeared when Salazopyrin was readministered.

Adult↗
PubMed1980

Oxygen affinity of hemoglobin in polycythemia of undetermined etiology.

High oxygen affinity hemoglobinopathy, as an eventual cause for polycythemia of undetermined etiology, was investigated in 40 unclassifiable polycythemia subjects. The determination of 2,3-diphosphoglycerate and P50 in the polycythemic and in the control groups has not demonstrated any sigificant difference between them. The routine search of this condition in similar patients does not seem to be warranted.

2,3-Diphosphoglycerate↗
PubMed1980

Life-threatening hypophosphatemia in a patient with acute myelogenous leukemia.

A patient with acute myelogenous leukemia developed severe hypophosphatemia manifesting by extreme weakness, confusion, loss of sphincter control, nuchal rigidity, hyperesthesia, hemolysis, congestive heart failure and liver dysfunction. The possible causes for this condition were starvation, parenteral glucose and saline administration, sepsis, hypokalemia and treatment with acetazolamide. A dramatic improvement was noted following phosphate administration.

Acetazolamide↗