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Biomedical subjects

J Phillips

Publications and source records attributed to J Phillips.

At least 343 records · Page 19Linked to original sources
PubMed1970

Polymorphonuclear leukocyte chemotactic activity in rabbit serum and Guinea pig serum treated with immune complexes: evidence for c5a as the major chemotactic factor.

A number of polymorphonuclear leukocyte (PMN) chemotactic factors derived from complement components have been described. We sought to determine which of these factors accounted for the majority of PMN chemotactic activity in rabbit serum and guinea pig serum treated with preformed immune complexes. Normal rabbit sera, guinea pig sera, or rabbit sera deficient in C6 were treated with homologous antibovine serum-albumin-bovine serum-albumin complexes. Sera so treated contained one major PMN chemotactic factor which was heat-stable (56 C for 30 min), had a molecular weight of approximately 15,000, and did not require the presence of C6 for its generation. This factor appears to be analogous to C5a.

Journal Article↗
PubMed1965

Lactic dehydrogenase isoenzymes in normal and pathological spinal fluids.

Spinal fluid lactate dehydrogenase (L.D.H.) isoenzyme patterns have been investigated in normal subjects, in those with non-destructive nervous disease, and in those with destructive lesions in the nervous system.The spinal fluid from organic disease in general showed a significantly increased level of L.D.H.(2) and L.D.H.(3) so that the combined values of L.D.H.(2) and L.D.H.(3) might perhaps be of value in determining the presence of destructive nervous lesions.

Cerebrospinal Fluid↗
PubMedDate not supplied

Malignant neuroendocrine tumor presenting in the mandible.

The carotid body, jugulotympanic, vagal, and laryngeal paragangliomas are the most common paragangliomas respectively within the head and neck, although unusual examples in other sites have been described. Among these are several references in the literature to a mandibular or "alveolar body" paraganglioma, even though such an entity does not appear to have been adequately documented. This report describes a case which presented as an extensive osteoblastic tumor involving the mandible and which radiographically appeared as a typical osteosarcoma. However, the immunohistochemical and electron microscopic features were of a neuroendocrine tumor and the histologic pattern suggested a paraganglioma. The tumor was nonfunctional and an extensive search failed to reveal any further lesions. Eight months after resection of the lesion, metastatic deposits appeared within the left iliac crest and lumbar vertebra. The origin of this tumor is discussed.

Aged↗