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Biomedical subjects

J Parnas

Publications and source records attributed to J Parnas.

At least 91 records · Page 5Linked to original sources
PubMed1975

[Toxicity of S-, R- and M-forms of enteropathogenic E. coli O149:K91:H10].

Toxicity of freeze-dried lysates of the organism for unweaned mice (3-4 days old) increased in the order:smooth-mucoid-rough. The toxicity was neutralized by mixing the toxin with immune serum of group O149. All toxins of the smooth, rough and mucoid variants of the Escherichia coli strain possessed hypersensitivity, skin necrosis, abortion and diarrhoea factors, which could be partly or completely neutralized by binding with homologous immune serum.

Animals↗
PubMed1975

[Infrared spectrophotometry of culture broth and toxins of enteropathogenic strains of Escherichia coli].

Lyophilized preparations of sterile broth, broth used for cultivation of enteropathogenic E. coli strains from which endotoxin and enterotoxin had been removed, were prepared for spectrophotometry by mixture with potassium bromide, and examined in heavy water. Despite basic biochemical differences, all the preparations showed similar or identical curves, with the same absorption maximum and wave length. The substances present in broth (proteins, lipids, sugars, etc.) were so dominant that that completely masked substances specific for E. coli and its toxins. Spectrophotometry revealed only the pattern belonging to broth, so that toxins can be only examined by this method after they have been separated from the broth. It is hoped to do this in the future.

Carbohydrates↗