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Biomedical subjects

J Palou

Publications and source records attributed to J Palou.

At least 145 records · Page 8Linked to original sources
PubMed1977

[Focal epidermal necrolisis. A variation of lupus erythematosus of a new disease?].

Four cases with clinical characteristics closely related to Lupus Erythematosus Disseminatum are reported by the authors. The evolution, progress and the biochemical, immunological and photobiological data were different from those usually found in L.E.D. The histopathological picture was also dissimilar, the most characteristic finding being a sharply limited epidermal necrolysis with focal distribution. In view of the peculiarities of the clinico-pathological syndrome presented by these patients, the authors raise the questions does it represent a special modality of L.E.D. or a new lupus-like disease?

Adult↗
PubMedDate not supplied

Evaluation of specific antigen and prostatic acid phosphatase specificity. Study of false values.

We assayed prostatic specific antigen (PSA) and prostatic acid phosphatase (PAP) serum levels in 1305 subjects without malignant prostatic pathology by double antibody RIA I125 to evaluate their specificity. When we set a second upper normal limit of 10 ng/ml for PSA and 2.5 ng/ml for PAP there was a significant increase of specificity. There were 2 and 3.7% false positive results in non-prostatic benign pathologies, 1.8 and 7.9% in non-prostatic malignant, 3.5 and 4.7% in non-complicated benign prostatic hypertrophy (BPH) and 3.3% for both in chronic prostatitis. In patients with complicated BPH and acute prostatitis the results were 64.8 and 24% for PSA and 20 and 16% for PAP. In conclusion, PSA is more specific than PAP in patients without acute inflammatory pathology of the prostate; the high rate of false positive values in the latter excludes its usefulness in these patients as diagnostic tumoral markers.

Acid Phosphatase↗
PubMedDate not supplied

Clinical utility of prostatic specific antigen and prostatic acid phosphatase serum levels in monitoring prostate cancer.

We analysed 696 prostatic specific antigen (PSA) and prostatic acid phosphatase (PAP) serum samples by double antibody radioimmunoassay (RIA)I125 in the follow-up of 122 patients with prostate cancer under treatment. PSA levels were significantly correlated to response to treatment, whereas PAP results did not differentiate patients with partial or complete remission. Progression of the disease was detected in 95.2 and 85.4% of PSA and PAP samples, and increased to 99.9% using both simultaneously. On the whole, PSA was better than PAP in monitoring prostate cancer, and the efficacy was greater using both markers together.

Acid Phosphatase↗
PubMedDate not supplied

Occurrence of Hodgkin's disease and cutaneous B-cell lymphoma in the same patient: a report of two cases.

The occurrence of Hodgkin's disease (HD) and non-Hodgkin's lymphoma (NHL) in the same patient is well known. The most frequent observation has been the development of large B cell lymphoma in patients affected with the nodular form of lymphocytic predominant HD. A less common situation is the development of NHL among patients successfully treated for HD. In such patients the second lymphoma has been thought to be related to the previous therapy or the immunodeficiency state that can accompany HD. Histologically, these NHL lymphomas often are intermediate to high grade and frequently extranodal. We report two patients successfully treated for HD who also developed NHL of the skin. Both patients presented with strikingly similar findings regarding to sex, age and subtype of HD. Clinical, histopathological and immunophenotypical findings were consistent with cutaneous low-grade B cell lymphoma of the marginal zone type. Both cases remain in complete remission of HD after standard therapy. In both patients the cutaneous lymphoma followed an indolent clinical course after a long follow-up period. This observation expands the spectrum of alterations possibly related to HD.

Adult↗
PubMedDate not supplied

[Giant cervical angioma caused by "malignant" arteriovenous fistulae].

A case of angioma by malignant AV fistula (described by F. Martorell in 1970) is reported. Such kind of fistulas have usually a lethal course. The case reported underwent a surgical correction, and after a following of 10 years, no major complications have been reported.

Adolescent↗
PubMedDate not supplied

[Echography and cystoscopy: 2 diagnostic means in bladder tumor (1)].

Study of 88 patients with vesical tumour who were performed a vesical ultrasound scan followed by cystoscopy. Comparison of both methods as to their ability to discriminate the location, size and number of the tumours. Both ultrasound scan and cystoscopy diagnosed vesical tumour in 81.8% and 100% cases respectively, the ultrasound scan showing higher ability to detect tumours affecting both sides of the bladder.

Cystoscopy↗
PubMedDate not supplied

[Evaluation of tumor staging using echography in bladder tumors (2)].

The paper shows the value of echography in tumoral grading based on 87 patients who besides cystoscopy, bimanual touch and histology study by transurethral resection, had an echography performed. Sensitivity achieved for tumour detection through echography was 85% with a positive predictor value of 98.8%. On the 72 patients who were diagnosed a tumour through echography, TUR histology showed an echography under-grading of 2.7% (2 cases) and an over-grading of 9.7% (7 cases) with grading correlation in 86.3% cases.

Cystoscopy↗
PubMedDate not supplied

[Thyroid metastasis of renal carcinoma].

Clinical detection of thyroideal metastasis of renal carcinoma is very rare; diagnosis of this type of metastasis is usually done at post-mortem examination. A case of thyroideal metastasis six years after nephrectomy due to renal carcinoma is presented. The slow evolution and good prognosis following surgical exercises justify an active therapy. Thirty-two months after the operation our patient is still free from the disease.

Adenocarcinoma↗
PubMedDate not supplied

[Urologic pathology in patients positive for anti-HIV antibodies].

Between May 1987 and November 1988 we performed the human immunodeficiency virus (HIV) antibody serological test on 586 patients of the Urology and Nephrology Services, and it was positive in 14 cases. Of these, 6 came on account of urological pathology: bilateral cryptorchidism, giant condylomata acuminata, acute pyelonephritis and three acute orchi-epididymitis. All the patients were intravenous drug addicts. Although it is a case of common urological pathology and not secondary to the acquired immunodeficiency syndrome, it takes on a different significance as regards the risk population in which it occurs.

Adult↗