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Biomedical subjects

J Palou

Publications and source records attributed to J Palou.

At least 109 records · Page 6Linked to original sources

[The Winer dilated pore].

Dilated pore (Winer) is a not uncommon adnexal benign tumor with follicular differentiation. Clinically the lesion looks like a giant comedo, usually located on the facial area of the elderly. Due to annular elevation of the borders, differential diagnosis needs to be made with basal cell epithelioma and senile sebaceous adenoma. The histology shows a typical infundibular dilatation with subinfundibular atrophy of hair structures. The authors report two typical cases of this badly known but not infrequent lesions.

Adenoma↗

[Lever's facial granuloma. Study using direct immunofluorescence in 2 cases].

Cases of two 48 and 55 year-old males affected of facial granuloma with eosinophilia are presented. In both cases direct immunofluorescence studies revealed the presence of IgG, IgA and C3 along the basement membrane. A brief comments on clinical and histological appearance, previous immunofluorescence studies, pathogenesis and treatment are made.

Eosinophilic Granuloma↗

Renal leiomyosarcoma in a patient with tuberous sclerosis.

We report the case of a 16-year-old patient with tuberous sclerosis that presented as renal leiomyosarcoma. This is an exceptional form of presentation of this tumor. An angiomyolipoma has to be first suspected in this group of patients. If the diagnosis is not confirmed by the imaging studies, radical surgery is recommended.

Adolescent↗

Wilms' tumor in an adult patient.

We present herewith a case of Wilms' tumor in an adult patient. He underwent radical surgery, chemotherapy (adriamycin, actinomycin, vincristine and cyclophosphamide) and radiotherapy. He is alive and free of disease after 48 months of follow-up.

Adult↗

Cutaneous malakoplakia. Report of a case.

A case of cutaneous malakoplakia in a 44-year-old women under immunosuppressive therapy after renal transplantation for nephrosclerosis is reported. A nodular lesion with inflammatory signs appeared on her right buttock. Histopathology showed a dermal infiltrate with histiocytes containing Michaelis-Gutmann bodies. Electron microscopy showed Michaelis-Gutmann bodies with concentric laminar structure ('target' appearance). Tissue culture revealed Escherichia coli growth. Lesions recurred on surrounding skin and left buttock after excision. Clofazimine treatment resulted in total remission.

Adult↗

Bone marrow prostatic specific antigen and prostatic acid phosphatase levels: are they helpful in staging prostatic cancer?

We analyzed serum and bone marrow levels of prostatic specific antigen and prostatic acid phosphatase quantified by double antibody radioimmunoassay in 70 patients. Of the patients 36 had prostatic cancer, including 23 with metastatic disease. There was a significant correlation between the serum and bone marrow levels of prostatic specific antigen and prostatic acid phosphatase independently of the metastases (p less than 0.001). No patient with prostatic cancer and positive bone marrow prostatic specific antigen or prostatic acid phosphatase levels had normal serum levels. Quantification of bone marrow prostatic specific antigen and prostatic acid phosphatase does not provide more information than does serum determination.

Acid Phosphatase↗

Primary cutaneous lymphoplasmacytic lymphoma.

A case of a primary cutaneous lymphoplasmacytic lymphoma synthesizing IgG lambda chains is reported. Immunohistochemical studies were done with the use of antihuman immunoglobulin antisera and monoclonal antibodies against T cell antigens. These studies reveal an unusual pattern of immunoglobulin production (IgG lambda chains) and an important population of accessory cells (T cells and Langerhans cells).

Adult↗

[Etiological variety of balanopreputial pigmentations].

The authors report 17 cases with a similar clinical pattern but corresponding to different processus: lentigo simplex, dermal and junction nevus, lichen planus, lentigo premalignant, secondary Incontinentia pigmenti. The diagnosis of the disorders was made by microscopical study.

Adolescent↗

Inflammatory myopathy associated with chronic graft-versus-host disease.

Damage of skeletal muscle in association with graft-versus-host disease (GvHD) has been referenced exceptionally. Eighteen months after bone marrow transplantation, a 22-year-old man developed polymyositis associated with manifestations of chronic GvHD, such as peripheral eosinophilia and localized morphea. Diagnosis of polymyositis was established by clinical, electromyographic, and histopathologic findings. His clinical condition improved with immunosuppressive therapy. At electronmicroscopy, some close and broad contacts between lymphocytes with activated appearance and degenerated muscle fibers were observed, suggesting a lymphocytotoxic mechanism. The findings support the idea that polymyositis can be considered a manifestation of chronic GvHD.

Adult↗