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Biomedical subjects

J Ovadia

Publications and source records attributed to J Ovadia.

At least 181 records · Page 10Linked to original sources
PubMed1975

The role of metal ions in the radiosensitivity of metalloproteins. Model experiments with bovine carbonic anhydrase.

The radiation-induced inactivation of dilute solutions of three forms of bovine carbonic anhydrase (metal-free apo-BCA, Zn2+-BCA and Co2+-BCA) has been studied. The presence of the metal ions did not alter the sensitivity of the enzyme to inactivation by oxidizing radicals; however, they exerted a protective effect against inactivation by reducing radicals. Data obtained using the amino-acid-specific inorganic radical anions (CNS)2-and Br2-allowed the identification of histidine, tyrosine and tryptophan as residues essential to the activity of bovine carbonic anhydrase when assayed by p-nitro-phenylacetate.

Carbonic Anhydrases↗
PubMed1975

Ultrastructural study of the erythropoietic events in human embryonic livers.

The ultrastructural features of the erythropoietic events in 5- to 9-week embryonic livers are described. By the 5th week of gestation, the human embryonic liver becomes an active site of erythropoiesis represented by the formation of reticular-mesenchyme cells and hemocytoblasts. At the 6--7th week, the first proerythroblasts and islands of polychromatophilic and orthochromatic erythroblasts can be detected. From this stage, by the 8th week of embryonic development, the liver assumes its function as a fully developed embryonic organ. In the embryonic livers studied there were no signs of granuloor lymphopoiesis. Although megakaryocytes were found in the 8-week embryonic liver, there is no evidence that these cells are produced in the liver. Macrophages were found in the 5-week embryonic liver.

Embryo, Mammalian↗