Search PubMed⌕ Search

Biomedical subjects

J Nyboe

Publications and source records attributed to J Nyboe.

61 records · Page 4Linked to original sources
PubMed1969

The immediate effects of BCG revaccination.

Although revaccination with BCG has been practised for many years, the effects of this procedure have not been studied in detail. This paper gives some results from a study of the immediate effects of revaccination, i.e., the lesion developing at the site of injection and the tuberculin sensitivity present after a few months. The data indicate that both of these responses are slightly stronger after revaccination than after first-time vaccination.The data collected in the study have confirmed that the tuberculin test has serious limitations when used for selecting candidates for revaccination.

BCG Vaccine↗
PubMed1967

Epidemiological basis of tuberculosis eradication. 9. Changes in the mortality of Danish tuberculosis patients since 1925.

The authors have carried out an analysis of the mortality among Danish patients with tuberculosis whose condition was diagnosed between 1925 and 1954 in order to obtain a picture of the trend of tuberculosis mortality over a period during which a dramatic improvement in the prognosis of the disease has taken place. The data originate from clinical records and follow-up during 10 years of all notified cases fulfilling certain conditions in Arhus, the largest provincial town in Denmark.The mortality of the patients was highest immediately after diagnosis and decreased during the 10 years they were followed. The relative changes during the follow-up period, however, appeared to be the same in all patient groups and this fact has greatly simplified the comparison of the mortality among patients diagnosed in the different calendar years.Analysis of the data according to year of diagnosis showed a consistent and substantial decrease in the mortality of young patients before the antituberculosis drugs came into use. This was true even within groups of patients with similar radiological findings. For patients over 45 years of age, however, there was no significant decrease in mortality before 1950.

Adolescent↗
PubMed1966

Evaluation of efficiency in interpretation of chest x-ray films.

Because of the inaccuracy inherent in mass chest radiography it would be desirable to have the chest films examined by the most efficient interpreters and to apply the film material that permits the most efficient interpretation. But before this can be achieved a method for an objective evaluation of efficiency must be developed.In the present paper a method is suggested for evaluating the efficiency of one important activity in film interpretation-namely, the determination of whether or not there is an abnormal opacity in a chest X-ray film. A test procedure is described that may be used for collecting the required data in respect of different interpreters and different types of film material. A discussion of the test data is presented and a method of analysis suggested. It is hoped that the general considerations concerning diagnostic efficiency given in this paper may be useful in the development of methods for evaluating other diagnostic procedures.

Humans↗
PubMed1966

Measurement of the incidence of tuberculous infection.

For certain purposes it is desirable to know the incidence of tuberculous infection in various population groups with a high degree of accuracy. The most accurate method for obtaining such information is the follow-up method, in which the population is tuberculintested on two separate occasions in order to determine the proportion who become infected with tubercle bacilli during the interval. The method is illustrated by means of data collected on children under 9 years old in Tunisia. The data indicate that the use of the same limit between "positive" and "negative" reactions in the two tests would lead to biased estimates of infection rates. A method of analysis involving the use of different limits has therefore been developed and applied to the data. The accuracy of the incidence rates obtained is indicated by a comparison of hypothetical prevalence rates computed from them with the observed prevalence rates.

Child↗