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J Molin

Publications and source records attributed to J Molin.

At least 19 recordsLinked to original sources
PubMed1997

Socioeconomic status and perinatal outcome according to residence area in the city of Malmö.

BACKGROUND: Maternal socioeconomic status is known to influence perinatal outcome. Antenatal care is free of charge in Sweden and all pregnant women are followed according to a standardized protocol of surveillance. The city of Malmö in southern Sweden is divided into 124 townships with great differences in socioeconomic standard. The aim of this study was to evaluate perinatal outcome according to the address of residence of the mothers within the city of Malmö. METHODS: Perinatal outcome of 7056 pregnancies was related to three socioeconomic characteristics of the 124 townships in Malmö: percentage of immigrants, percentage of inhabitants on social welfare and the median income. RESULTS: Maternal age was lower, number of abortions and parity were higher in low income areas. Perinatal complications were also more frequent, including low birthweight, small-for-gestational age newborns, maternal anemia, infections, and low 1- and 5-minute Apgar scores. Premature rupture of membranes was associated with low income areas. Symphysiolysis and pre-eclampsia were more frequent in the high income areas. CONCLUSION: Although maternity care is provided free of charge, perinatal complications were more frequent in areas of lower socioeconomic status. In order to improve perinatal outcome, antenatal surveillance should be intensified in low class socioeconomic areas.

Female↗
PubMed1997

A regional perinatal database in southern Sweden--a basis for quality assurance in obstetrics and neonatology.

BACKGROUND: In order to ensure as few avoidable adverse outcomes of pregnancy as possible, it is necessary to continuously evaluate the quality of both obstetric and neonatal care. The eleven southernmost hospitals in Sweden have joined together in a project of developing a regional database, with special emphasis on rapid output of information in order to identify changing trends. METHODS: A regional computerized database has been developed, collecting variables and quality indicators agreed upon by all participants. Specific protocols have been designed for obstetric care, neonatal care and autopsy findings. All participating units transfer information on paper forms or via local computerized information systems. The regional database thus receives data on about 20,000 deliveries annually. RESULTS: Data collection started on September 1, 1994. The first results are due in March 1996, and thereafter on a regular basis every 3 months. Special methods for rapid analysis of raw data have been developed with the help of commercially available data analysis tools. CONCLUSIONS: It is possible to construct an information system with different computer platforms and different database tools at each participating facility, as long as the database systems are locally controllable. That a software is commercially available is no guarantee that data transfer to a central database is possible. Experience from participating sites also indicates that a specialized database is needed for registering obstetric data, as general computerized record-keeping systems are unable to cope with an event concerning more than one subject at a time.

Female↗
PubMed1996

The influence of climate on development of winter depression.

126 patients suffering from winter depression participated in the study. Every second week patients completed the 13 item Beck Depression Inventory (BDI) in the period September to May in the years 1991 to 1994. Local weather data from this period were obtained from the Meteorological Institute, Copenhagen. No significant correlation was found between score on BDI and cloud cover, rainfall or atmospheric pressure. A significant correlation was found between score on BDI and minutes of sunshine, global radiation, length of daylight and temperature. This is in accordance with the theory, that lack of light is a contributing factor for development of winter depression.

Adult↗
PubMed1996

No additional metal particle formation using the needle-through-needle combined epidural/spinal technique.

BACKGROUND: Combined epidural/spinal analgesia utilizing a needle-through-needle technique has become very popular in anesthesia. However, findings of concave deformities at the orifice of Tuohy needles after spinal needle passage have raised concerns that metal fragments might be deposited within the epidural space. This study was proposed to investigate whether the needle-through-needle technique does produce metallic flecks. METHODS: Ten unused Tuohy and Hustead epidural needles were inspected microscopically and photomicrographed prior to flushing saline through each into a single tissue culture well. After drying, a single pass was made with a 120 mm 24-gauge Sprotte needle through each epidural needle to maximal extension while the orifice was within another tissue culture well. Each needle was again flushed into a third well before reexamination and photomicroscopy. Each of the wells was inspected for metallic particles by microscopy. Additional freshly unpackaged Tuohy needles were microscopically examined after exposure to a magnetic field. RESULTS: Comparison of micrographs before and after needle experiments revealed concave deformities at the orifice of all the Tuohy and Hustead needles. No particles were observed in either of the two saline-flushed wells or within the well in which the needle-through-needle passes were made. Inspection of unused Tuohy needles exposed to a magnetic field revealed metal filings "standing up" along the bevel of every needle examined. CONCLUSIONS: Metallic particles are not produced by the needle-through-needle technique. However, metal particles are an apparent contaminant of all epidural needles and are probably routinely introduced into patients when the needle is placed.

Analgesia, Epidural↗
PubMed1994

Study of the interaction of dextran and enoxaparin on haemostasis in humans.

The effect on haemostatic variables by dextran 70, enoxaparin and their combinations, given in doses of 500 ml i.v. and 40 mg s.c. respectively, was studied in a randomised cross-over fashion in twelve healthy male volunteers. Antifactor-IIa activity, antifactor-Xa activity, APTT, factor VIII, vWF, bleeding time and blood counts were analysed over a 24-h period. Dextran alone did not affect antifactor-IIa activity and antifactor-Xa activity. No difference in antifactor-IIa and antifactor-Xa activity was found for Amax, tmax, AUC0-8 h and AUC0-24 h in the groups treated with enoxaparin or the combination of enoxaparin and dextran. Only minor changes in APTT were observed without statistical significance between the treatment groups. Factor VIII did not change significantly in the three treatment groups. However, vWF was significantly reduced in the dextran and the dextran/enoxaparin group (p = 0.046 and 0.01 respectively) but no difference was found between the two groups. Bleeding time was not significantly increased four hours after administration of the test substances and no difference was found between the individual treatment groups. Our findings indicate that dextran can be combined with enoxaparin, when used in thromboprophylactic doses, without increased risk for bleeding.

Adult↗
PubMed1993

Platelet paroxetine binding and light therapy in winter depression.

The effect of light therapy on serotonin uptake capacity in patients suffering from winter depressions (seasonal affective disorders) was examined indirectly by using [3H]paroxetine binding to determine the number of platelet serotonin transporters. In patients who responded to light therapy the number of platelet serotonin transporters decreased significantly following treatment. In contrast, patients who did not respond to light therapy were found to have a relatively low number of serotonin transporters prior to treatment, and the number did not change significantly following treatment.

Adult↗