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Biomedical subjects

J Miskowiak

Publications and source records attributed to J Miskowiak.

71 records · Page 4Linked to original sources

Bypass revision in unsatisfactory weight loss after jejunoileal bypass for morbid obesity.

Sixteen patients with unsatisfactory weight loss after end-to-side jejunoileal bypass were treated with either simple resection of the elongated segment of the shunt (10 patients) or resection combined with conversion to an end-to-end anastomosis (Scott) (6 patients). This led to an additional median weight loss of 13.5 kg (range, 3-25 kg) after 1 year. Scott's procedure yielded the greatest weight loss, but the price was bypass enteritis, arthritis, or electrolyte disturbances in all but one patient. Two of these patients required conversion to gastroplasty. After simple resection of the shunt less than half of the patients required electrolyte supplementation. Most of these patients, however, had unsatisfactory weight loss, which necessitated further surgery in five patients. Only 6 of the 16 patients had good results. In consequence, we have for the past 2 years used conversion to gastroplasty in patients with unsatisfactory weight loss after jejunoileal bypass.

Adult↗

Sclerotherapy of bleeding esophageal varices. Long-term results.

Sixty-one patients presenting with hemorrhage from esophageal varices were treated with sclerotherapy by means of a fiberoptic endoscope. Twenty-nine had acute bleeding, which was stopped in 90%. Thirty-two were treated after recent bleeding. The hospital mortality was 31%. Re-bleeding occurred in 55% of those discharged but was easily controlled. Fatal complications occurred in 5%. The calculated 4-year survival was 35%. Two thirds of this mortality could be attributed to liver failure. The intellectual function of the patients appeared to be unaffected.

Adult↗

Scintigraphic diagnosis of gastrointestinal bleeding with 99mTc-labeled blood-pool agents.

Abdominal scintigraphy with 99mTc-labeled albumin or red blood cells was used in 68 patients to localize gastrointestinal bleeding or confirm that it had stopped. Acute, active bleeding was identified in 33 patients; characteristic patterns of bleeding from the stomach, biliary passages, small intestine, and colon are shown. Sensitivity was 0.86 (95% confidence limits, 0.57-0.98) and specificity was 1.0 (95% confidence limits, 0.82-1.0) in 33 patients who had scintigraphy and endoscopy performed in succession. Abdominal scintigraphy appears to be a valuable supplement to conventional diagnostic methods. In upper gastrointestinal bleeding, scintigraphy should be considered when endoscopy fails. In lower intestinal bleeding, scintigraphy should be the method of choice.

Adolescent↗

Acute gastrointestinal bleeding detected with abdominal scintigraphy using technetium-99m-labeled albumin.

In 24 patients admitted with gastrointestinal bleeding 36 scintigraphic studies of the abdomen were performed after intravenous injection of technetium-99m-labeled albumin. In 12 patients bleeding from the esophagus, stomach, duodenum, biliary tract, or colon was visualized. In the other 12 patients, in whom the bleeding seemed to have subsided, the investigation showed no scintigraphic signs of hemorrhage. Scintigraphy was also negative in five controls who had no bleeding. The method is non-invasive and easy to perform. Our study suggests that it is reliable, but a controlled trial is necessary to evaluate the diagnostic value of the method.

Acute Disease↗

How the lower oesophageal sphincter affects submucosal oesophageal varices.

Oesophageal varices are found in the submucosa of the lower oesophageal sphincter (L.E.S.). Portagraphic studies after vasopressin administration showed occlusion of submucosal oesophageal varices and distension of the para-oesophageal veins. Oesophagography and endoscopy after administration of anticholinergics showed considerable dilatation of the submucosal oesophageal varices. Because vasopressin increases, and anticholinergics decrease, L.E.S. pressure it is suggested that L.E.S. pressure is an important factor in the development of submucosal oesophageal varices.

Blood Pressure↗

Abdominal scintiphotography with 99mtechnetium-labelled albumin in acute gastrointestinal bleeding. An experimental study and a case-report.

In a new diagnostic method in acute gastrointestinal bleeding, after an intravenous injection of 99mtechnetium-labelled albumin, the distribution of radioactivity in the abdomen is followed for 40-60 minutes by sequential scintiphotography. The site of simulated gastrointestinal bleeding could be identified in all five volunteers. In a patient with severe bleeding from diverticula in the sigmoid colon the method gave a correct estimate of the site of the bleeding and of its rate.

Abdomen↗

Radiologic findings and weight loss following gastroplasty for morbid obesity.

Gastroplasty aimed at treatment of morbid obesity creates a small proximal pouch and a narrow stoma to the remainder of the stomach. In 11 consecutive obese patients subjected to gastroplasty radiologic examinations of the stomach were performed before operation and one week, 3 and 12 months postoperatively. All stomachs were normal before operation. A significant decrease in pouch area and increase in stoma diameter were registered over the observation period. There were no statistically significant correlations between postoperative weight loss and stoma diameter or pouch area. Nor was retention in the pouch one week after gastroplasty related to weight loss. Radiographic evidence of gastroesophageal reflux was present in only one patient. The described method of follow-up is evidently not suited to predict the outcome of gastroplasty.

Adult↗

Tetracycline sclerotherapy of hydroceles and epididymal cysts. Long-term results.

Fourty patients with 32 hydroceles and 11 epididymal cysts were treated by aspiration and instillation of tetracycline. After a follow up period of 24-39 months the cure rate was 77%. Most of the early recurrences were the results of chemical inflammation and vanished spontaneously. This group should therefore not be operated on until three months after their initial treatment. As aspiration of the fluid had allowed palpation of the testis and cytological examination, only a small proportion of patients with recurrences wanted further treatment. We therefore recommend tetracycline sclerotherapy because it is quick, easy, safe, and effective in the long as well as the short term.

Aged↗