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Biomedical subjects

J Mendelson

Publications and source records attributed to J Mendelson.

At least 91 records · Page 5Linked to original sources
PubMed1975

Disseminated gonorrhea: diagnosis through contact tracing.

Over a 1-year period four patients were seen at the Jewish General Hospital with presumed disseminated gonococcemia. The patients' histories, clinical findings and responses to therapy strongly supported this diagnosis; however, cultures from various sites were negative for Neisseria gonorrhoeae in all four patients. Sexual contacts of these patients were traced and appropriate cultures were found to be positive, demonstrating the importance of tracing sexual contacts to help confirm the diagnosis in such patients.

Adult↗
PubMed1975

Self-inoculation with milk as a cause of recurrent cellulitis.

A 21-year-old patient had six admissions to hospital for recurrent cellulitis over a 6-month period. She underwent extensive investigations, which failed to reveal any underlying predisposing factors. On the final admission she admitted to injecting herself subcutaneously with milk to induce the lesion. Self-inoculation with foreign material must be considered in patients presenting with recurrent cellulitis.

Adult↗
PubMed1975

Correlation between in vivo and in vitro metabolic measurements. Maximum capacity for urea synthesis.

Estimations of enzyme activity in vivo have been or can often only be done at unphysiological conditions. A main biochemical goal is to correlate in vivo and in vitro measurements. A possible approach to this problem is presented based on forcing metabolic activity in vivo to the maximum for a certain metabolic sequence. Since the urea synthesis system, including maximal rates of enzyme activities, is well known, we have compared in vitro maximum rates for the individual enzymes of urea synthesis with in vivo rates as judged by urea levels in blood of rats given large amounts of protein. The excellent agreement found between the calculated maximum activities from in vitro measurements to the time needed to metabolize a protein overload is presented and comments made on its significance and on the importance of maintaining protein intake at moderate levels, for the capacity of the urea system is limited. Since the intake of large quantities of protein increases the urea level in blood and in other tissues and since high urea levels are somewhat deleterious "per se" and particularly due to equilibrium with cyanate, ingestion of excessive amounts of protein is at best expensive and possibly hazardous.

Animals↗
PubMed1974

Meningococcal meningitis: an atypical case.

A case of meningococcal meningitis is described in a patient who had not received antibiotics before admission. Three lumbar punctures were performed over a seven-day period, but only the cerebrospinal fluid from the third yielded a positive culture. The importance of repeated lumbar punctures in patients with undiagnosed meningitis is emphasized.

Adult↗
PubMed1974

Brill-Zinsser disease: report of a case in Canada.

This report documents the occurrence of Brill-Zinsser disease in a 48-year-old woman who experienced typhus fever in a German concentration camp. This is the first report of a case of recrudescent typhus in a European immigrating to Canada following World War II. The last reported case of Brill-Zinsser disease in Canada occurred in 1953.

Canada↗
PubMed1974

Asymptomatic gonorrhea in the male.

In a prospective study, 133 male contacts of 102 women with gonorrhea were examined. A diagnosis of gonorrhea was made in 63 patients, indicating an infection rate of 47% after exposure. Forty-three percent of the patients with gonorrhea were asymptomatic. The duration of the asymptomatic period ranged from 3 to 154 days. The epidemiologic importance of this hidden infectious reservoir is stressed.

Canada↗