Onchocerciasis in members of an expedition to Cameroon: role of advice before travel and long term follow up.
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Adult↗
Biomedical subjects
J McLeod
Publications and source records attributed to J McLeod.
Pseudo-outbreak of blastomycosis associated with contaminated bronchoscopes.
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Blastomycosis↗
Effect of 12-O-tetradecanoylphorbol-13-acetate (TPA) on substance P-induced histamine release from rat peritoneal mast cells.
12-O-tetradecanoylphorbol-13-acetate (TPA, 1 to 30 ng/ml) produced a dose-related inhibition of substance P (SP)-induced histamine release from rat peritoneal mast cells. TPA itself induced some histamine release over this concentration range (maximum release about 20% of total). Maximum inhibition of SP-induced release by TPA required preincubation with TPA for at least 10 min. The inhibitory action of TPA was observed in the absence as well as in the presence of extracellular calcium (0.4 mM). Inhibition of diacylglycerol kinase by R 59022 or of diacylglycerol lipase by RHC 80267 reduced SP-induced histamine release. Oleolylacetylglycerol (OAG, 50 microM) inhibited histamine release induced by SP but was less potent than TPA. It is concluded that protein kinase C activation in rat peritoneal mast cells is associated with inhibition of SP-induced histamine release.
Animals↗
Educational underachievement: toward a defensible psychometric definition.
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Child↗
What the domestic found.
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Hospitals, Psychiatric↗
Ventilatory abnormalities in hospital admissions.
The incidence of unrecognised ventilatory impairment was investigated in a group of 531 routine hospital admissions who had been considered to be free of significant respiratory disease. Using spirometric tests of FEV 1, FVC and FEV 1/FVC percent before and after sympathomimetic bronchodilator, it was found that 42 percent of these patients had abnormal ventilatory tests, and 47 percent were considered to have obstructive lung disease. Routine use of screening respiratory function tests would be useful in the assessment and management of general medical and surgical hospital admissions.
Adolescent↗
The sweet life.
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Attitude of Health Personnel↗