[Case of the month: median presellar tumor].
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Biomedical subjects
Publications and source records attributed to J Masselot.
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CT scans were performed in 16 children with undifferentiated epitheliomas of the cavum nasopharyngis type. The CT scan provided the most precise data during initial investigations, especially clear information being obtained on any intra-orbital or intracranial extension, which may occur without clinical signs. The scan is also a valid method for determining efficacy during treatment, and for the early detection of recurrences.
Malignant histiocytosis (MH) is a disease which clinically and histologically resembles non-Hodgkin lymphoma. Tumoural cells appear to be derived from histiomonocytes. Clinical signs commonly include: high fever, sudden onset of extreme fatigue, diffuse painful polyadenopathies and infiltrated cutaneous nodules. This study involved the radiological findings of 23 pediatric cases of MH. Thoracic involvement is very frequent (69%) and most often involves mediastinal lymph nodes. Interstitial (34%) and pleural (38%) lesions are often associated. Nine of 21 (42%) lymphographies showed pathologic changes, the most frequent pattern in retroperitoneal nodes was multilacunar and nodes were moderately enlarged. Some isolated lymph nodes were normal. Bone lesions were rare and were either lytic or sclerotic.
The aim of pre-operative radiologic localization is to facilitate surgery by reducing operation time and by limiting the size of excision of a benign lesion. The detection technique, the so-called "crochet" method, is described and compared with others reported in the literature. Using this method, 33 nonpalpable lesions were detected over a 6 month period and 15% of these cases had malignant tumors.
Computed tomography (CT) has already proved extremely effective both in cerebral and abdominal pathology. Several recent publications describing first heterogeneous series [1, 2, 7, 11-17], then studies of a single type of lesion [3-6, 8] have illustrated its usefulness in the study of bone lesions. This report deals with 41 cases of Ewing's sarcoma studied by CT at the Institut Gustave Roussy from October 1977 to July 1981, and tries to show both the limitations and indications of this technique for the diagnosis, treatment, and follow-up of Ewing's sarcoma as well as in the diagnosis of any eventual recurrence.
The number, the variety and the complexity of investigations for diagnosis and follow-up of ovarian carcinoma are related to the diversity of possible involvement and the insufficiency of the reliability of each of the applied methods. Cytologic examination, sonography and CT scanning are of first line importance, as well as the different roentgenologic methods. However, none allows dispensing surgical exploration and pathological examination. Moreover, as one speaks of therapeutic strategy, diagnostic strategy lead by a homogeneous and well coordinated team, is worthy of mention as well, for it is the only guarantee for efficiency and valuable results.
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In order to study the possible advantages of thoracic CT scanning in the management of mediastinal lymphomas, a retrospective analysis of 16 patients was carried out. In this group, 21 thoracic CT scans were performed. For 10 patients (and 11 CT scans) we found a discrepancy between the results of "classical" radiology and those of CT scan, the latter giving more information about the precise status of the mediastinum. In 10 cases, we had to modify our treatment, either by adding chemotherapy or changing the radiation field size.
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Thirty seven children with neuroblastoma were investigated by CT-scan. Twenty three of them underwent surgery allowing anatomical correlation. CT-scan was of little diagnostic help but proved very helpful in assessing the extent of the tumor: CT-scan and surgery were in agreement in 73% of the operated cases. CT is therefore an accurate means of predicting the operability of neuroblastoma.
Clinical, radiological, and histological problems arise relating to fibrous dysplasia of the maxilla. Clinically, 11 of our 39 cases developed so rapidly that the lesions were suspected of being malignant. The histological diagnosis may be very difficult, since any tumoural, reactive, or healing process may simulate fibrous dysplasia. As a general rule, the diagnosis is established most easily by the radiological examination. The radiologist's responsibility is important, as mistakes may have serious consequences. We report four pseudotumoural forms of maxillary sinus fibrous dysplasia. All were characterised clinically by rapid evolution, radiologically by opacity of the sinus with apparent destruction of its wall, and histologically by difficulty in establishing the diagnosis. In two cases indeed, the initial histological interpretation was an osteogenic sarcoma. Due to its excellent densitometric resolution, computed tomography provides an invaluable contribution by displaying the fibrous wall of an intact or even thickened maxillary sinus when conventional radiology has suggested a destructive process. In difficult cases of maxillary fibrous dysplasia, computed tomography should be used as a supplementary investigation to establish the correct diagnosis.
Computed tomography examinations, using a second generation Acta 200 FS apparatus, were conducted on 28 occasions in 25 patients with hepatic carcinoma. Before injection, the tumor is usually of low density, to a small degree in many cases, and is heterogeneous and has indefinite limits. The sensitivity of the method is 96 p. cent. A precise study of the localization of the tumor was possible in only 11 cases, and a definite diagnosis was made in 64 p. cent. The method was only moderately effective in assessing the degree of regional extension. When compared with other methods for the investigation of the liver (scintigraphy, ultrasonography, arteriography), computed tomography shows no superiority over ultrasonography which should be employed for the initial examination.
Radiolesions of the pelvic bones (excluding the femur) were observed in 29 patients after irradiation therapy for cervix uteri cancer. Three regions can be affected corresponding to the areas irradiated: the sacrum and internal part of the iliac wings, the pubis, and the cotyles. In most cases the lesions appeared after 1 to 4 years. Their radiological appearances are characteristic, the principal sign being irregular bone condensation in a demineralized bone, without true cavitation. The only lytic lesions observed were in the pubis. Calcification of soft tissues may occur and fractures are frequent. There is a slow progression of the lesions over long periods. Clinical, radiological, and progression signs differentiate radiolesions from other affections: metastases, invasion by contiguity, infections, and radio-induced sarcoma.
Diagnosis of a left subphrenic abscess after splenectomy is often difficult. C.T. scanning was used to establish the diagnosis in 5 patients with subphrenic abscesses. The examination is simple and gives valid results. Needle aspirations, controlled by scanning, can confirm the diagnosis or be used for drainage of the abscess.
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