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Biomedical subjects

J Mann

Publications and source records attributed to J Mann.

At least 361 records · Page 20Linked to original sources

Oral hygiene among Israeli kibbutz youth.

The purpose of this study was to assemble up-to-date information regarding oral hygiene status among Israeli kibbutz adolescents 14-17 years of age. The oral hygiene status of 465 teenagers in 10 kibbutzim was determined. The findings indicate a relatively better oral cleanliness as compared with past results in Israel for similar age groups. It was suggested that the nature and structure of the kibbutz way of life, family and peers strongly influences kibbutz teenagers' oral hygiene practices.

Adolescent↗

Prevalence of dental caries and demands for services among Israeli kibbutz youth.

The purpose of the present study was to assembly information regarding caries prevalence among adolescent residents of kibbutzim in Israel. A total of 465 teenagers in 10 kibbutzim were examined for dental caries experienced. The DMFT figures derived in the study were almost double the values recorded for a comparable kibbitz age groups in the later 60's. Mean DMFT values were found to increase with age. The mean number of decayed teeth (D) showed a similar distribution. The proportion of teenagers free of caries was 1.5% and only 2.3% did not require any treatment. Despite the overwhelming need for dental care noted among kibbutz youth, only 21.6% were receiving care of their dental needs. Since physical blocks to access to dental care are almost non-existent in the kibbutz, it was suggested that the reason for the high rates of unmet needs, could, at least partially, be attributed to fear of pain and anxiety about the treatment.

Adolescent↗

Safety data on zimelidine hydrochloride following an overdose.

Zimelidine, a new antidepressant, has proved to be a potent and selective inhibitor of 5-HT uptake into central 5-HT neurons. Due to its structural differences from the tricyclic antidepressants, it has also been suggested that it may have a different pharmacological profile, and be devoid of anticholinergic and noradrenaline potentiating properties. During the treatment with zimelidine hydrochloride, as a part of an open trial, one of our patients, a 38-year-old chronically depressed woman, overdosed herself with more than 10 times the actual therapeutic dose of zimelidine with no undesirable side effects. Previous studies have indicated that zimelidine in comparison with imipramine and chlorimipramine has no, or at most, a slight effect on peripheral adrenergic neurons, and has less pronounced anticholinergic properties than imipramine. The findings of our overdose case provide some support for these findings.

Adult↗

Loss of periodontal attachment in adolescents.

Loss of attachment as measured by a portion of Ramfjord's Index (PDI) was determined in 383, 12-16-year-old schoolchildren in rural Juniata County, PA. Prevalence and distributions were tabulated for sex, last dental visit, and type of treatment received. Dental knowledge test scores, toothbrushing effectiveness periodontal status and oral cleanliness were determined at annual intervals from Spring '75 to Spring'79. Mean scores were contrasted with bone loss measurements. 47.3% had loss of attachment (greater than 1 mm) including 24.5% with 2mm or more of attachment loss per mouth. Females (41.0%) ahd significantly lower prevalence rates than males (52.7%). Students who visited a dentist in the last 6 months and who received scaling had less bone loss, lower GI, PII, PI, and QHI scores. An inverse relationship was found between dental knowledge and the other variables measured. Similar patterns were seen with high, medium and low bone loss groups. Many variables in this study were associated with bone loss, including: plaque, dental knowledge, dental behavior (toothbrushing and visiting a dental clinic), recent treatment received and sex. None appeared more significant than the others.

Adolescent↗

The third component of complement: covalent attachment of a radioactive sugar to the labile binding site of C3 via the alternative pathway.

A complement- (C) fixing particle consisting of agarose beads to which 5-thioglucose was attached by a --S--S-- bond (agarose-thioglucose) was employed to investigate the mechanism of attachment of C3 to surfaces. When whole serum containing [125I] C3 was incubated with agarose-thioglucose, labeled C3b was taken up in a form that was not removed by 2 M NaCl but was released by 10 mM dithiothreitol. Deposition of DTT-releasable C3b was dependent upon the alternative pathway of C activation. Gel electrophoresis of DTT-releasable C3b from similar experiments performed with unlabeled serum and agarose-[3H]thioglucose showed that the liberated C3b contained a molecule of radioactive thioglucose attached to the alpha'-chain by a covalent bond that was stable to mercaptoethanol. We propose that the thioglucose-alpha' chain bond was formed during the course of C activation by a reaction between the "labile binding site" of newly released C3b and the (then) particle-bound sugar. This formulation implies that the reaction by which C3b attaches to 5-thioglucose in this system is the reaction responsible for opsonization by C3b, and that the C3b-linked sugar represents a marker for the labile binding site. Incubation of the particle-bound C3b in serum resulted in the cleavage of the covalently linked alpha'-chain to several smaller polypeptides, the major cleavage product having a m.w. of 70,000.

Binding Sites↗

Application of the periodontal treatment need system (PTNS) in a group of young Israeli adults.

The Periodontal Treatment Need System (PTNS) was applied to a group of young Israeli adults, 18-25 years of age, to test the system in the field. A total of 830 persons were examined. Their periodontal treatment needs were assessed. One of the aspects investigated was that of treatment needs according to distribution by sex. Only 2.7% of young adults studied were free of plaque, calculus and gingival inflammation. All the rest (97.3%) needed some kind of periodontal treatment. The time required for treatment needed was also calculated. It was found that on the average 2.4 h per person would be required to deliver the periodontal treatment needs of the group. A close association between sex and PTNS was established in this study.

Adolescent↗

Inter- and intra-examiner variability in scoring supragingival plaque: I. The clinical study.

Twenty-four normal healthy patients were scored for plaque by four examiners with different professional backgrounds and different levels of training. Each patient was examined twice by each examiner according to a predetermined random assignment with the assumption of no change in state. All four examiners scored higher on the second examination and there was no apparent consistent relationship between professional background and level of training in the plaque scoring.

Dental Hygienists↗

Acute fluoride poisoning in a New Mexico elementary school.

Thirty-four persons became ill with acute fluoride poisoning shortly after drinking water in an elementary school in Los Lunas, NM. The water supply of the school was supplemented with a concentrated sodium fluoride solution designed to raise fluoride levels in drinking water to 1 to 5 ppm. Two water samples taken after the incident was reported showed elevated fluoride levels of 375 and 93.5 ppm. Malfunction of a relay switch controlling dilution of the fluoride solution produced toxic fluoride levels in the water. The symptoms of all patients were mild and generally of short duration, with two thirds of patients reporting complete resolution within 24 hours. The bitter, salty taste of the water deterred consumption of large amounts and prevented serious intoxication.

Acute Disease↗