Biomedical subjects

J M Jackson

Publications and source records attributed to J M Jackson.

At least 73 records · Page 4Linked to original sources

PubMed1977

Angioimmunoblastic lymphadenopathy with dysproteinemia.

Three cases of angioimmunoblastic lymphadenopathy with dysproteinemia are reported which illustrate the characteristic clinico-pathological features. These cases also provide information relating to the ultrastructure of the interstitial acidophil material, the histopathological spectrum, where treatment has been attempted, and an incidence figure for an Australian community. Detailed immunological investigations in one case suggest that the disease is a primary B-lymphocyte abnormality.

Adult↗

PubMed1976

Thrombotic thrombocytopenic purpura--remission following splenectomy. Report of a case and review of the literature.

A case of thrombotic thrombocytopenic purpura in which sustained remission followed splenectomy is described. Strong serologic evidence of concurrent infection with Mycoplasma pneumoniae was found in this case. Previously reported cases in which thrombotic thrombocytopenic purpura has been associated with infections are reviewed. An approach to management of this unusual and frequently fetal condition, is suggested, based on a detailed review of the recent literature.

Adolescent↗

PubMed1976

Escherichia coli mutants with altered ribosomal ribonucleic acid metabolism.

This paper reports the partial characterization of two temperature-sensitive mutants of Escherichia coli with alterations in ribosomal ribonucleic acid (rRNA) metabolism at the restrictive temperature. Both mutants continue to synthesize deoxyribonucleic acid and protein at 42 C but showed little or no accumulation of RNA. Both strains are inducible for beta-galactosidase at the restrictive temperature, showing that messenger RNA synthesis continues and that the messenger RNA is translated into functional protein. One of the strains, 2S474, shows a rather severe depression (sevenfold) in the synthesis of all classes of RNA at 42 C. In addition, the synthesis of rRNA is selectively depressed, with the percentage of rRNA synthesis. However, there appears to be a selective depression in the rate of rRNA synthesis and, possibly, in the conversion of p16S rRNA to m16S rRNA.

Bacterial Proteins↗

PubMed1974