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Biomedical subjects

J M Coget

Publications and source records attributed to J M Coget.

51 records · Page 3Linked to original sources

[Klippel-Trenaunay, syndrome or disease].

Two cases which were clinically typical of the Klippel Trenaunay syndrome and in which the integrity of the deep venous system demonstrated by phlebography form the basis for the author's discussion of the various theories and classifications which have been put forward up to now. The authors favour Schobinger's opinion, according to which three varieties of the Klippel Trenaunay syndrome are recognised. Malan's anatomoclinical classification has been adopted : this permits the grouping together of the numerous variations possible in this type of dysplasia.

Adult↗

[Klippel-Trenaunay syndrome of the upper extremity. Apropos of 2 cases].

The authors report a case of Klippel-Trenaunay syndrome in the upper limb of a 27 years old migrant manual worker. This very typical case due to agenesis of the humeral vein is used as a basis for a discussion of the theories of Servelle on the pathogenesis of this syndrome.

Abnormalities, Multiple↗

[Microcirculation of the skeletal muscle].

There are certain claudications deriving from over-intense or over-prolonged muscular activity, caused by excessive tissular pressure in the fascial cavity of the leg, anterior rather than lateral. This usually occurs in young subjects who are athletic, sportive, or soldiers. The clinical symptom is a sudden jab, like a whip-crack, both painful and paretic. The direct measurement of tissular pressure, using the needle method, confirms the excess of pressure already high when the patient is resting; it rises manifestly with muscular effort and slowly falls again after it. The pressure-gradient calls for fasciotomy in hyperalgetic cases from a certain tissular pressure-gradient onwards. Phlebography has shown the venous collapse and clinical attention is often in these cases to the presence of "muscular hernia" in the leg. Clinical data are self-explanatory and Reneman recently recalled this with a case of capillaro-venular stasis, followed by an excess of permeability and the formation of interstitial oedema which has a restraining effect. Structures and functions of the microcirculation of the skeletal muscle enable us to understand the phenomena.

Arterioles↗

[Post-traumatic ulcers in the elderly subject].

The occurrence of ulceration after minor traumatism in the older patient free from arterial disorders, can be explained by the decreased elasticity of the subcutaneous tissues, which thus provokes arterial rupture, which in turn brings on major bruising and the appearance of an area of necrosis whose surface is proportionately large or smaller according to the damage done to the arterioles. The treatment is straight forward, and usually leads to quick healing without scarring.

Aged↗

[Lymphatic drainage and lymphovenous anastomosis. Treatment of lymphedema of the lower extremities].

The treatment of lymphoedema of the lower limbs is often rather disappointing, at the present time. However, two simple surgical techniques, lympho-venous anastomosis and lymphatic drainage, seem to complement existing methods and should improve the clinical course of constitutional and secondary lymphoedema. These simple techniques are based on the pathophysiology of the lymphoedema and certainly represent a hope in the treatment of some swollen legs.

Drainage↗

[Errors caused by taboos].

The treatment of varicose veins, indeed of all phlebopathies, is still the butt of quite singular superstitions, firmly entrenched in the mind of the practitioner. Few treatments in the twentieth century are so denigrated as those of varices and leg ulcers. This may well be due to negligence, but there are many who denounce either the surgical or the sclerotherapeutic treatment of varices and leg-ulcers in aged or obese patients, in women going through genital or menopausal phases, and in pregnant women. Of course there are certain contraindications, but one thing is certain: there should be better information available for the general practitioner, so that he can gain a better idea of the therapeutic approach to these illnesses.

Age Factors↗

[True or false varicose veins in sportsmen? (Result of a survey)].

The incidence of varicose veins remains high, as is proved by official statistics, particularly those of the Army, the average level being given at about 35 per cent, at least in France. A recent statistic produced at the Centre for the Detection of Cardiovascular Disease of the Urban Community of Lille, fairly homogeneous and representative of the North Region, has shown that the incidence is 20 per cent for one or the other saphenous vein in a population of more than 1 500 subjects of mean age 34 years. This study was permitted a distinction between true varicose veins and simple venous swellings, and we can now raise the question of the responsibility of swelling in the high level of varicose veins sometimes reported in competitive athletes, especially in elevated places. The study concerns three population groups, the first unselected (20 per cent varicose veins, 11 per cent swellings), the second consisting of 120 licensed athletes (14 per cent varicose veins, 12 per cent swellings), and the third group consisting of 330 Brigade Firemen (14 per cent and 11 per cent). Swelling was assessed in part by an electronic processor though not with statistically valid precision and the search for valvular incompetence was carried out simply and economically by listening to the Doppler Signal. Very often a very small localised double souffle was heard at the exact site of the venous projection. This raises again the spinous pathogenesis of Piulachs and Vidal-Barraquer, which is discussed and accepted in the unambiguous case.

Adult↗

[Sclerosis of the external saphenous vein and compartment syndrome].

Despite the precautions taken during sclerosis of the arch of the external saphenous, the authors describe four patients who presented a clinical picture of acute pain, developing about two hours after the injection, accompanied by induration of the internal gemellus and contracture of this muscle, leading to functional disability; recovery from this was not really complete until the end of six months. They explain this picture not by the injection of an artery frequently present at the level of the popliteal junction, but injection of a gemellar ven, giving rise to a compartment syndrome; this hypothesis has not received any confirmation by arteriography or phlebography.

Compartment Syndromes↗

[Veno-lymphatic correlations and communications].

We are far from being thoroughly acquainted with lympho-venous pathology, despite minute research in this field. The only physiological lympho-venous communications are macroscopic. The existence of microscopic communications has been proved in animals, but it seems that anastomoses become pathologically normal whenever the lymph flow is at all checked. It should be particularly noted that the vasculo-tissular equilibrium is precariously dependent on the physiological condition. The slightest disturbance can upset this balance, resulting in the formation of lympho-venous anastomoses, which attempt to set up a balance difficult to maintain.

Animals↗

[Complications of superficial venous surgery of the legs: thigh hematomas and abscess].

A series of 1,000 patients has been studied. I. HEMATOMAE: They are nearly continuous during internal saphena stripping but depend on various parameters. 1) Anatomical: a) Varicose veins topography. Perforating veins. Perforating veins of the thigh cause haemorrhage but reactions of venous construction are quite important and precocious not to observe subcutaneous bleedings. More or less "soft" stripping creates a reaction of reflex vasoconstriction. Fore saphenous vein of the thigh Hematomae are more and more numerous and important because the fore saphenous vein is a vein whose wall is thinner, more fragile and almost more superficial. b) Type of patient. In an obese patient, hematoma seems to be more spectacular. In the thin patient, it appears faster, if hematic expression is too late. 2) Stripping techniques: It is possible to propose different techniques of stripping, but none of them can lower specifically post-surgical hematomae. 3) Anaesthesiae: a) General anaesthesia. A bilateral surgery under general anaesthesia was helpful to observe in some cases a less important hematoma at the level of the second operated leg. b) Rachi-anaesthesia. Physiological vasoconstriction requires a latent period for this kind of anaethesia which causes a vasomotor paralysis due to a blockade of the sympathetic nerve. c) Local anaesthesia. It is obtained by crural block in association with injection of Xylocaine Adrenalina at the level of perforating veins of the thigh. This technique causes less hematomae. II. ABSCESSES: Only 4 cases out of 1,000 operated legs have been reported. No related pathology have been observed particularly about lymphatic disorders (erysipelas or lymphoedema), no previous infection known which could not have explained such complications. Therapy was simple: incision at mid-thigh and draining by lamina. The patient recovered within two weeks.

Abscess↗

[Atrophie blanche].

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Atrophy↗