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Biomedical subjects

J Lissner

Publications and source records attributed to J Lissner.

At least 127 records · Page 7Linked to original sources

[Clinical result of thyroid scintigraphy and iodine estimations using a fluorescent technique (author's transl)].

The new technique of quantitative fluorescent scintigraphy was used for determining the regional distribution and concentration of stable intrathyroid iodine (127 I) in 96 patients. Average iodine concentration in normal people (20 individuals) without thyroid enlargement living in the Bavarian iodine-deficiency area was 0.38 +/- 0.07 mg/g. In 32 patients with simple goitres it was significantly lower at 0.17 +/- 0.06 mg/g. With this technique it was possible to separate two types of hyperthyroidism amongst 21 patients: those with low iodine concentration in the thyroid (0.15 +/- 0.08 mg/g) and those with high iodine concentration (0.42 +/- 0.12 mg/g) after iodine administration. The iodine concentration in decompensated autonomous adenomas in twelve patients was usually low (0.12 +/- 0.12 mg/g). On the other hand iodine concentration was high in the paranodular tissues and could be demonstrated on the fluorescent scintigram. The quality of the scintigram using this technique for concentrations below 0.1 mg/g is inadequate. In this situation good imates can be obtained by radionucleid scintgrams. The situation is reversed by previous administration of iodine.

Diagnosis, Differential↗

CT studies of the liver in vitro: a report on 82 cases with pathological correlation.

Eighty-two liver specimens were studied by both computed tomography (CT) and pathological examination with serial sectioning. In vitro CT studies showed low density structures within 57 normal livers to be due to portal and hepatic vessels but not to bile ducts. A liver with a minimum of 70% fatty infiltration could be diagnosed correctly on CT. Concerning the presence or absence of circumscribed liver disease, sensitivity was 80% and specificity was 84%. With respect to the total number of space occupying liver lesions (n = 364 in 18 specimens), sensitivity was 72%. The smallest metastases detectable on CT were 0.5 cm in diameter, but CT disclosed focal lesions of this small size in only 15% of the cases. In contrast to previously reported in vivo CT studies, metastases were often found to be of higher density than normal liver tissue in vitro.

Diagnostic Errors↗

[Value of computerized tomography in diseases of liver and spleen].

A survey has been given regarding the position of the CT as a examination method of liver, gallbladder - bile duct system and spleen. A fast scanner of the third generation has been used and has been compared with results of a slow CT of the first generation.

Diagnosis, Differential↗

Computerized tomography and nuclear imaging of the liver: a comparative study in 83 cases.

This study was performed to comparatively assess the diagnostic accuracy of computerized tomography (CT) and nuclear liver-scanning in detecting and defining circumscript and diffuse liver diseases in 83 patients. Presence or absence of liver diseases was assessed based on the results of invasive diagnostic procedures such as biopsy, laparoscopy, laparotomy, and/or autopsy. The percentage of true negative diagnoses was 94% for CT and 91% for static gamma-imaging (n = 33). With a rate of 94% true positive diagnoses, CT proved to be superior to gamma imaging with radiocolloids (81% true positives) in diagnosing circumscript liver diseases (n = 31). In addition. CT was superior to nuclear imaging regarding discrimination of number and size of space-occupying lesions within the liver. In contrast to nuclear screening, CT scans were pathognomonic to some circumscript liver diseases such as cysts, metastases, and perhaps echinococciasis. This was also true for obstructive jaundice. Nuclear imaging, because it reflects a sort of liver function, was superior with cirrhosis, whereas CT showed only alterations in the size and shape of the liver and spleen.

Abscess↗

[Preoperative and postoperative stomach evacuation studies via methods of nuclear medicine and methods of roentgen cineradiography (author's transl)].

A combination of roentgen cineradiography and functional scintigraphy of stomach evacuation, taken with a gamma camera, was used for assessing the success of organ-conservative surgery of ulcers (selective proximal phagotomy with or without pyloroplasty). This confirmed earlier results to the effect that surgical failure is not indicated with any measure of certainty by any individual roentgenologic symptom. However, the evacuation function is closely correlated with the pattern of clinical and subjective complaints. In most of the cases, rapid postoperative stomach evacuation results in freedom from complaints. Pyloric stenosis and retention point to the failure of the operation via the negatively effected subjective feeling of well-being. Hence, special importance must be attached to functional scintigraphy with regard to meaningful studies of the course and postoperative condition of the patient.

Gastric Emptying↗

[Xeroradiography in the diagnosis of skeletal diseases (author's transl)].

The value of xeroradiography in the diagnosis of peripheral skeletal lesions is illustrated by some typical examples and compared with standard radiographic procedures. The advantages of xeroradiography depend on its convenient format, easy appreciation of structural changes and easy viewing. On the other hand, density gradations are flattened. Compared with a technically satisfactory film examination, there is no increase in diagnostic information. Xeroradiography can therefore only be regarded as complementary to conventional radiography for the diagnosis of skeletal conditions.

Bone Diseases↗

Computed tomography in hydatid disease of the liver: a report on 13 cases.

Computed tomography (CT) findings in hydatid disease (echinococciasis) of the liver are described. Disease was caused by Echinococcus granulosus (n = 8) or E. alveolaris (n = 5), respectively. The CT appearance of these two types of echinococciasis is quite different; in disease caused by E. granulosus the CT appearance is pathognomonic when cysts and daughter cysts surrounded by a capsula and peripheral calcification are discernible. In addition, the extent of organ involvement can be determined prior to surgical intervention. The CT appearance of E. alveolaris lesions may be indiscernible from malignant tumors.

Calcinosis↗

Diagnostic accuracy of CT in circumscript liver disease.

To evaluate the accuracy of CT in diagnosing circumscript liver disease, CT findings in 105 patients were compared to the results of invasive diagnostic procedures (laparoscopy, laparotomy, and autopsy). In all patients at least one of these procedures was performed in addition to CT. CT proved to be a valuable noninvasive method in detecting and differentiating circumscript liver lesions such us metastases, primary liver tumors, solitary cysts and polycystic disease, abscesses, and echinococciasis. The 10% rate of false positive and false negative diagnoses indicates the limitations of the method.

Autopsy↗

[Radiological bone patterns compared with pathological and anatomical appearances (author's transl)].

In the present study, radiographs of the skeleton were compared with relevant pathological sections; in this way some information could be more clearly brought out and changes in the structure and contours of bones could be classified. The radiographs were compared with photographs of the actual specimen. For this purpose either plain radiographs or tomographic cuts were used. In addition, bone sections were studied by a radiographic magnification method in order to improve detail recognition.

Bone Diseases↗

[Computerised tomography of the trunk-a first report (author's transl)].

One thousand patients have been examined with the body scanner and a preliminary report is presented on the value of this method in the examination of abdomen and the thorax. Unlike other radiological procedures, computerised tomography is often able to demonstrate disease states directly and not only as a result of their effect on neighbouring structures. It provides a non-invasive means for achieving a diagnosis, for therapy planning and for control of treatment of space-occupying lesions within the trunk. Its role can only be defined after a systematic comparision with conventional diagnostic procedures.

Bronchial Neoplasms↗

[Special indications for using the whole body scanner (author's transl)].

In addition to the role of the body scanner in the diagnosis of diseases of the body cavity and parenchymal organs, the authors review the scope and indications for using whole body computer tomography in special situations. Examples are given of its use in the diagnosis of tumours in the vicinity of the skull base, in the orbits, the facial skeleton, soft tissue tumours, bone diseases and CT-controlled biopsies.

Adult↗